Charalambos Fotakis
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View article: Editorial: Omics approaches to delineate the role of gut microbiota-derived metabolites in obesity and metabolic disorders
Editorial: Omics approaches to delineate the role of gut microbiota-derived metabolites in obesity and metabolic disorders Open
Obesity is a complex chronic disorder with a multifactorial etiology that involves genetics, hormones, diet, and environmental stimuli (1). It is considered a medical condition that may trigger complications, such as metabolic syndrome, hi…
View article: The Metabolic and Antioxidant Activity Profiles of Aged Greek Grape Marc Spirits
The Metabolic and Antioxidant Activity Profiles of Aged Greek Grape Marc Spirits Open
In the last decade, “expressions” of grape marc spirits aged in wooden barrels of characteristic amber color and complex sensory attributes have been introduced. Yet studies on constituents migrating from the barrel to the beverage are sca…
View article: Circulatory Metabolite Ratios as Indicators of Lifestyle Risk Factors Based on a Greek NAFLD Case–Control Study
Circulatory Metabolite Ratios as Indicators of Lifestyle Risk Factors Based on a Greek NAFLD Case–Control Study Open
An ensemble of confounding factors, such as an unhealthy diet, obesity, physical inactivity, and smoking, have been linked to a lifestyle that increases one’s susceptibility to chronic diseases and early mortality. The circulatory metabolo…
View article: Serum metabolomic profiling unveils distinct sex-related metabolic patterns in NAFLD
Serum metabolomic profiling unveils distinct sex-related metabolic patterns in NAFLD Open
Objective Obesity poses an increased risk for the onset of Nonalcoholic fatty liver disease (NAFLD). The influence of other factors, such as sex in the incidence and severity of this liver disease has not yet been fully elucidated. Thus, w…
View article: Maternal Dietary Protein Patterns and Neonatal Anthropometrics: A Prospective Study with Insights from NMR Metabolomics in Amniotic Fluid
Maternal Dietary Protein Patterns and Neonatal Anthropometrics: A Prospective Study with Insights from NMR Metabolomics in Amniotic Fluid Open
This study aimed to characterize dietary protein patterns (DPPs) in a sample pool of 298 well-nourished pregnant women and explore potential associations between DPPs and neonatal anthropometrics. Maternal dietary data were collected using…
View article: Urine Metabolomic Profile of Breast- versus Formula-Fed Neonates Using a Synbiotic-Enriched Formula
Urine Metabolomic Profile of Breast- versus Formula-Fed Neonates Using a Synbiotic-Enriched Formula Open
The aim of this study was to compare the urine metabolic fingerprint of healthy neonates exclusively breastfed with that of neonates fed with a synbiotic-enriched formula (Rontamil® Complete 1) at four time points (the 3rd and 15th days of…
View article: Uncontrolled Thyroid during Pregnancy Alters the Circulative and Exerted Metabolome
Uncontrolled Thyroid during Pregnancy Alters the Circulative and Exerted Metabolome Open
Normal levels of thyroid hormones (THs) are essential for a normal pregnancy outcome, fetal growth and the normal function of the central nervous system. Hypothyroidism, a common endocrine disorder during pregnancy, is a significant metabo…
View article: Insights into intrauterine growth restriction based on maternal and umbilical cord blood metabolomics
Insights into intrauterine growth restriction based on maternal and umbilical cord blood metabolomics Open
View article: Linking the IL-17A immune response with NMR-based faecal metabolic profile in IBD patients treated with Mastiha
Linking the IL-17A immune response with NMR-based faecal metabolic profile in IBD patients treated with Mastiha Open
View article: Front face synchronous fluorescence as a tool for the quality assurance of Greek milk
Front face synchronous fluorescence as a tool for the quality assurance of Greek milk Open
This research focuses on implementing the low cost and rapid front face synchronous fluorescence (SyFS) in order to ensure the quality assurance of Greek milk. Specifically, samples originated from the Greek domestic production of goat, sh…
View article: Expanding the Role of Sub-Exploited DOE-High Energy Extraction and Metabolomic Profiling towards Agro-Byproduct Valorization: The Case of Carotenoid-Rich Apricot Pulp
Expanding the Role of Sub-Exploited DOE-High Energy Extraction and Metabolomic Profiling towards Agro-Byproduct Valorization: The Case of Carotenoid-Rich Apricot Pulp Open
Traditional extraction remains the method-of-choice for phytochemical analyses. However, the absence of an integrated analytical platform, focusing on customized, validated extraction steps, generates tendentious and non-reproducible data …
View article: On the Characterization and Correlation of Compositional, Antioxidant and Colour Profile of Common and Balsamic Vinegars
On the Characterization and Correlation of Compositional, Antioxidant and Colour Profile of Common and Balsamic Vinegars Open
Commercially available common and balsamic vinegars were examined, using a combination of spectrophotometric, chromatographic, colorimetric and spectroscopic methods. Total phenolic content, antioxidant activity, radical scavenging capacit…
View article: 1H NMR-based metabolomics reveals the effect of maternal habitual dietary patterns on human amniotic fluid profile
1H NMR-based metabolomics reveals the effect of maternal habitual dietary patterns on human amniotic fluid profile Open
View article: Design, synthesis and biological evaluation of new substituted 5-benzylideno-2-adamantylthiazol[3,2-b][1,2,4]triazol-6(5 H )ones. Pharmacophore models for antifungal activity
Design, synthesis and biological evaluation of new substituted 5-benzylideno-2-adamantylthiazol[3,2-b][1,2,4]triazol-6(5 H )ones. Pharmacophore models for antifungal activity Open
As a part of our ongoing studies in developing new derivatives as antimicrobial agents we describe the synthesis of novel substituted 5-benzylideno-2-adamantylthiazol[3,2-b][1,2,4]triazol-6(5H)ones.The twenty-five newly synthesized compoun…
View article: Assessment of lactation stage and breed effect on sheep milk fatty acid profile and lipid quality indices
Assessment of lactation stage and breed effect on sheep milk fatty acid profile and lipid quality indices Open