Charity N. Njeshi
YOU?
Author Swipe
View article: Effects of emodepside on single-channel properties of Onchocerca volvulus SLO-1A (BK) potassium channels
Effects of emodepside on single-channel properties of Onchocerca volvulus SLO-1A (BK) potassium channels Open
Background Control of onchocerciasis (river blindness of humans due to infection with the filarial nematode, Onchocerca volvulus ) remains a challenge because of the lack of effective adulticides and vaccines. Emodepside is a broad-spectru…
View article: Positive allosteric modulation of emodepside sensitive Brugia malayi SLO-1F and Onchocerca volvulus SLO-1A potassium channels by GoSlo-SR-5-69
Positive allosteric modulation of emodepside sensitive Brugia malayi SLO-1F and Onchocerca volvulus SLO-1A potassium channels by GoSlo-SR-5-69 Open
Human lymphatic filariasis and onchocerciasis are Neglected Tropical Diseases (NTDs), of major public health concern. Prophylaxis and treatment rely on anthelmintics that effectively eliminate migrating microfilariae but lack efficacy agai…
View article: Effects of Emodepside on Single-Channel Properties of Onchocerca volvulus SLO-1A (BK) Potassium Channels
Effects of Emodepside on Single-Channel Properties of Onchocerca volvulus SLO-1A (BK) Potassium Channels Open
Background: Control of onchocerciasis (river blindness of humans due to infection with the filarial nematode, Onchocerca volvulus) remains a challenge because of the lack of effective adulticides and vaccines. Emodepside is a broad-spectru…
View article: Positive allosteric modulation of emodepside sensitive <i>Brugia malayi</i> SLO-1F and <i>Onchocerca volvulus</i> SLO-1A potassium channels by GoSlo-SR-5-69
Positive allosteric modulation of emodepside sensitive <i>Brugia malayi</i> SLO-1F and <i>Onchocerca volvulus</i> SLO-1A potassium channels by GoSlo-SR-5-69 Open
Human lymphatic filariasis and onchocerciasis are Neglected Tropical Diseases (NTDs), of major public health concern. Prophylaxis and treatment rely on anthelmintics that effectively eliminate migrating microfilariae but lack efficacy agai…
View article: Emodepside: the anthelmintic’s mode of action and toxicity
Emodepside: the anthelmintic’s mode of action and toxicity Open
Nematode parasitic infections continue to be a major health problem for humans and animals. Drug resistance to currently available treatments only worsen the problem. Drug discovery is expensive and time-consuming, making drug repurposing …