Andrew C. Johnson
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View article: Temporal Increases in Mercury Concentrations are Associated with Increased Risk of Death by Infectious Disease in Harbour Porpoises ( <i>Phocoena Phocoena)</i>
Temporal Increases in Mercury Concentrations are Associated with Increased Risk of Death by Infectious Disease in Harbour Porpoises ( <i>Phocoena Phocoena)</i> Open
Trace elements, particularly heavy metals like mercury, pose significant risks to marine ecosystems due to their toxic and bioaccumulative properties. Concentrations in some marine species show concerning temporal increases, yet spatiotemp…
View article: Zinc and Copper Have the Greatest Relative Importance for River Macroinvertebrate Richness at a National Scale
Zinc and Copper Have the Greatest Relative Importance for River Macroinvertebrate Richness at a National Scale Open
It is important to discover what change led to the improvement in European macroinvertebrate biodiversity in the period from 1990-2000s and what prevents further desirable gains from taking place today. A 30-year data set from 1,457 macroi…
View article: Ensuring representative sample volume predictions in microplastic monitoring
Ensuring representative sample volume predictions in microplastic monitoring Open
A large body of literature is available quantifying microplastic contamination in freshwater and marine systems across the globe. “Microplastics” do not represent a single analyte. Rather, they are usually operationally defined based on th…
View article: River invertebrate biodiversity benefits from upstream urban woodland
River invertebrate biodiversity benefits from upstream urban woodland Open
In urban environments, invertebrate communities are subjected to a broad mixture of impacts, including diffuse pollution. Pollutant mixtures and habitat degradation can combine to apply stress on community diversity. Water quality is influ…
View article: Identifying freshwater invertebrate taxa susceptible to AChE-acting pesticides
Identifying freshwater invertebrate taxa susceptible to AChE-acting pesticides Open
Globally pesticide use has been associated with negative impacts on riverine invertebrate communities, but chronic exposure effects to most specific groups of pesticides are not well understood. In this paper, we sought to identify inverte…
View article: Bridging the Gap: Advancing Ecological Risk Assessment from Laboratory Predictions to Ecosystem Reality
Bridging the Gap: Advancing Ecological Risk Assessment from Laboratory Predictions to Ecosystem Reality Open
National Natural Science Foundation of China (42322710)\nNational Key Research and Development Program of China (2021YFC3200105).
View article: Fate and behaviour of Microplastics (> 25µm) within the water distribution network, from water treatment works to service reservoirs and customer taps
Fate and behaviour of Microplastics (> 25µm) within the water distribution network, from water treatment works to service reservoirs and customer taps Open
Water treatment works have previously shown high efficiency in removing microplastics > 25 µm from raw source water. However, what is less well known is the extent to which microplastics of this size class are generated or lost within the …
View article: Assessment of the impacts of GABA and AChE targeting pesticides on freshwater invertebrate family richness in English Rivers
Assessment of the impacts of GABA and AChE targeting pesticides on freshwater invertebrate family richness in English Rivers Open
Globally, riverine system biodiversity is threatened by a range of stressors, spanning pollution, sedimentation, alterations to water flow, and climate change. Pesticides have been associated with population level impacts on freshwater inv…
View article: Pesticide pollution associations with riverine invertebrate communities in England
Pesticide pollution associations with riverine invertebrate communities in England Open
Globally freshwater biodiversity has experienced major decline and chemical pollutants are believed to have played a significant role in this decline, but this has not been well quantified for most riverine invertebrate populations. Here w…
View article: Invertebrate biodiversity continues to decline in cropland
Invertebrate biodiversity continues to decline in cropland Open
Modern agriculture has drastically changed global landscapes and introduced pressures on wildlife populations. Policy and management of agricultural systems has changed over the last 30 years, a period characterized not only by intensive a…
View article: Supplementary Figures from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Supplementary Figures from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
Supplementary Figure 1: BKM120 inhibited CD4+ T cell, not CD8+ T cell proliferation and had small effects on PyMT specific T cell mediated cytotoxicity only at a 1:50 E/T cell ratio. Supplementary Figure 2: Tumors were initiated as describ…
View article: Supplementary Methods from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Supplementary Methods from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
This file describes additional methodology
View article: Data from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Data from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
Purpose: Metastatic breast cancers continue to elude current therapeutic strategies, including those utilizing PI3K inhibitors. Given the prominent role of PI3Kα,β in tumor growth and PI3Kγ,δ in immune cell function, we sought to determine…
View article: Supplementary Methods from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Supplementary Methods from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
This file describes additional methodology
View article: Data from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Data from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
Purpose: Metastatic breast cancers continue to elude current therapeutic strategies, including those utilizing PI3K inhibitors. Given the prominent role of PI3Kα,β in tumor growth and PI3Kγ,δ in immune cell function, we sought to determine…
View article: Supplementary Figures from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
Supplementary Figures from PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses Open
Supplementary Figure 1: BKM120 inhibited CD4+ T cell, not CD8+ T cell proliferation and had small effects on PyMT specific T cell mediated cytotoxicity only at a 1:50 E/T cell ratio. Supplementary Figure 2: Tumors were initiated as describ…
View article: Consistent apparent adult survival and nest‐site fidelity of whimbrel <i>Numenius phaeopus</i> near Churchill, Manitoba, Canada over a 40 year period
Consistent apparent adult survival and nest‐site fidelity of whimbrel <i>Numenius phaeopus</i> near Churchill, Manitoba, Canada over a 40 year period Open
Reliable estimates of adult survival for many shorebird species are lacking. We used Cormack–Jolly–Seber (CJS) methods to provide an estimate of apparent, or local, survival (φ) of a population of whimbrels, Numenius phaeopus , breeding in…
View article: A Horizon Scan to Support Chemical Pollution–Related Policymaking for Sustainable and Climate-Resilient Economies
A Horizon Scan to Support Chemical Pollution–Related Policymaking for Sustainable and Climate-Resilient Economies Open
While chemicals are vital to modern society through materials, agriculture, textiles, new technology, medicines, and consumer goods, their use is not without risks. Unfortunately, our resources seem inadequate to address the breadth of che…
View article: Transport and transformation of perfluoroalkyl acids, isomer profiles, novel alternatives and unknown precursors from factories to dinner plates in China: New insights into crop bioaccumulation prediction and risk assessment
Transport and transformation of perfluoroalkyl acids, isomer profiles, novel alternatives and unknown precursors from factories to dinner plates in China: New insights into crop bioaccumulation prediction and risk assessment Open
Perfluoroalkyl acids (PFAAs) are contaminants of global concern, and the inadvertent consumption of PFAA-contaminated crops may pose a threat to public health. Therefore, systematically studying their source tracing, bioaccumulation predic…