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Stanley Desmond Smith. 3 March 1931 — 1 August 2023 Open
Desmond (Des) Smith was a key figure in the UK’s early development of lasers and optoelectronics, leading the Department of Physics of the newly recognized Heriot-Watt University from 1970 until his retirement in 1996. Having initially mad…
View article: DEVELOPMENT OF A NOVEL FRAMEWORK TO INFORM COST-EFFECTIVENESS MODELS IN SYSTEMIC LUPUS ERYTHEMATOSUS
DEVELOPMENT OF A NOVEL FRAMEWORK TO INFORM COST-EFFECTIVENESS MODELS IN SYSTEMIC LUPUS ERYTHEMATOSUS Open
PV094 / #450 Poster Topic: AS11 - Epidemiology and Public Health Background/Purpose Cost-effectiveness models (CEMs) play a significant role in health technology assessments (HTAs). However, existing CEMs for systemic lupus erythematosus (…
Development of a comprehensive genome-wide cardiovascular disease genetic risk assessment test Open
Background: Despite monogenic and polygenic contributions to cardiovascular disease (CVD), genetic testing is not widely adopted, and current tests are limited by the breadth of surveyed conditions and interpretation burden. Methods: We de…
Comparative Analysis of Aviation and Ground Transportation Safety Standards Applicable to the Integration of Unmanned Aircraft Operations Open
This study performed a comparative analysis of SMS in both the aviation and ground transportation industries to identify any gaps that may impact aviation safety by incorporating UAS operations within the ground transportation industry. Th…
Adaptive Domain Generalization for Digital Pathology Images Open
In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts …
Precipitation of light elements from Earth’s liquid core: Can exsolution power the ancient geodynamo? Open
Earth’s core currently sustains a geodynamo through chemical convection in the liquid outer core. This power source originates from the growth of the solid inner core, where light elements are partitioned to the liquid at the lower m…
MACHINE LEARNING-BASED PREDICTION OF GEBOES SCORE AND HISTOLOGIC IMPROVEMENT AND REMISSION THRESHOLDS IN ULCERATIVE COLITIS Open
BACKGROUND Histology is emerging as a key therapeutic endpoint for ulcerative colitis driven by associations between histologic response and long-term outcomes. However, existing scoring systems are subjective and consequently have variabl…
Cost-Effectiveness of Triple Therapy with Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate versus Dual Therapies in Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: United Kingdom Analysis Using the ETHOS Study Open
Based on ETHOS data, BGF was demonstrated to be cost-effective versus LAMA/LABA and ICS/LABA dual therapies at the conventional UK-adopted willingness-to-pay threshold (ICUR <£20,000). The main cost-effectiveness driver for BGF versus LAMA…
High Mass Flow Rate in a BAL Outflow of Quasar SDSS J1130+0411 Open
We present the analysis of the absorption troughs of six outflows observed in quasar SDSS J1130+0411 ($z \approx 3.98$) with radial velocities ranging from $-2400$ to $-15,400$ km s$^{-1}$. These spectra were taken with the Very Large Tele…
View article: 136 The use and efficacy of ffr-ct – a real-world multi-centre audit of clinical data and cost-analysis
136 The use and efficacy of ffr-ct – a real-world multi-centre audit of clinical data and cost-analysis Open
Introduction UK and US Guidelines now recommend HeartFlow FFR-CT (Fractional Flow Reserve-Computed Tomography) in stable chest pain (CP), but its clinical effectiveness and costs in real-world practice are not known. Our objectives were to…
Malaysia: University campuses blending local with international Open
International campuses are learning by doing, integrating local knowledge and approaches to world-class institutions. Universities have been slow to globalise. In the late 1980s there were only 30 or so international campuses: students mov…
Leading the Future - an Exploration of the Intern Perceptions of the Pharmacy Competency Standard ‘Leadership and Management’ Open
Background: Pharmacy is dynamic committed to the health of patients. During the severe acute respiratory syndrome coronavirus (COVID-19) pandemic, pharmacists were required to introduce new practice protocols and manage legislative changes…
BEACH SLOPES FROM SATELLITE-DERIVED SHORELINES Open
The slope of the beach face is a critical parameter for coastal scientists and engineers studying sandy coastlines. However, despite its importance for coastal applications (engineering formulations, coastal flood modelling, swimming safet…
Beach slopes from satellite-derived shorelines Open
The steepness of the beach face is a fundamental parameter for coastal morphodynamic research. Despite its importance, it remains extremely difficult to obtain reliable estimates of the beach-face slope over large spatial scales (1000’s of…
Beach slopes from satellite-derived shorelines Open
The steepness of the beach face is a fundamental parameter for coastal morphodynamic research. Despite its importance, it remains extremely difficult to obtain reliable estimates of the beach-face slope over large spatial scales (1000’s of…
Beach-face slopes from satellite-derived shorelines along SE Australia and California Open
This repository contains the data described in Vos, K., Harley, M. D., Splinter, K. D., Walker, A., & Turner, I. L. (2020). Beach Slopes From Satellite‐Derived Shorelines. Geophysical Research Letters, 47(14), e2020GL088365. There are 2 GE…
Beach-face slopes from satellite-derived shorelines along SE Australia and California Open
This repository contains the data described in Vos, K., Harley, M. D., Splinter, K. D., Walker, A., & Turner, I. L. (2020). Beach Slopes From Satellite‐Derived Shorelines. Geophysical Research Letters, 47(14), e2020GL088365. There are 2 GE…
DIORAMA Nuclear Cloud Lofting Module Validity Range Open
This document investigates the region of validity of the DIORAMA nuclear cloud lofting module based on two separate factors: i) continuum fluid assumptions breaking down and ii) where ballistic effects become significant.
Automation of Active Space Selection for Multireference Methods via Machine Learning on Chemical Bond Dissociation Open
Predicting and understanding the chemical bond is one of the major challenges of computational quantum chemistry. Kohn−Sham density functional theory (KS-DFT) is the most common method, but approximate density functionals may not be able t…
Automation of Active Space Selection for Multireference Methods via Machine Learning on Chemical Bond Dissociation Open
Predicting and understanding the chemical bond is one of the major challenges of computational quantum chemistry. Kohn−Sham density functional theory (KS-DFT) is the most common method, but approximate density functionals may not be able t…
DREAM utilizing real-time Van Allen probe data Open
It is demonstrated that it is imperative to use both EFW potential measurements and the HOPE instrument ion charging line for examining times of extreme spacecraft charging of the Van Allen Probes. The results of this study show that eleva…
Emulating satellite drag from large simulation experiments Open
Obtaining accurate estimates of satellite drag coefficients in low Earth orbit is a crucial component in positioning and collision avoidance. Simulators can produce accurate estimates, but their computational expense is much too large for …
ISR-1 Seminar: Nuclear Cloud Lofting Open
This report goes into detail about motivation, background, lofting methodologies (empirical, parcel methods, Navier-Stokes), DELFIC Model, validation, DIORAMA integration, and has the following conclusions: A parcel methodology was applied…