Charles E. Alex
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View article: A novel herpesvirus in blue penguins putatively associated with myocardial degeneration and necrosis
A novel herpesvirus in blue penguins putatively associated with myocardial degeneration and necrosis Open
We identified a novel herpesvirus in 2 deceased captive blue penguins ( Eudyptula minor ). Moderate-to-severe myocardiocyte atrophy and necrosis, and eosinophilic intranuclear inclusion bodies (INIBs), were seen in myocardiocytes in one bi…
View article: Prevalence of red panda amdoparvovirus infection in European zoos
Prevalence of red panda amdoparvovirus infection in European zoos Open
Red panda amdoparvovirus (RPAV) was first described in captive red pandas ( Ailurus fulgens ) at a zoo in the United States in 2018. Subsequently, the prevalence of infection in zoos in the United States was reported to be 50%; however, RP…
View article: A practical approach to the sampling, fixation, softening, and sectioning of whole honey bees for histologic evaluation
A practical approach to the sampling, fixation, softening, and sectioning of whole honey bees for histologic evaluation Open
The Western honey bee ( Apis mellifera) is economically important as the primary managed pollinator of many agricultural crops and for the production of various hive-related commodities. Honey bees are not classically or thoroughly covered…
View article: Fatal cerebrovascular accident in a captive red panda (Ailurus fulgens fulgens) with concurrent amdoparvovirus infection
Fatal cerebrovascular accident in a captive red panda (Ailurus fulgens fulgens) with concurrent amdoparvovirus infection Open
We report the pathological and molecular findings in an adult male Himalayan red panda (Ailurus fulgens fulgens) whose death was attributed to parenchymal brain haemorrhage (PBH) of the thalamus. Post-mortem examination revealed severe, ac…
View article: Amdoparvovirus-associated disease in striped skunks (<i>Mephitis mephitis</i>)
Amdoparvovirus-associated disease in striped skunks (<i>Mephitis mephitis</i>) Open
Disease caused by the archetypical amdoparvovirus (APV), Aleutian mink disease virus (AMDV), has been well studied, but APV infections in other carnivores are poorly understood. Skunk amdoparvovirus (SKAV), one of a handful of newly discov…
View article: AMDOPARVOVIRUS INFECTIONS ARE PREVALENT, PERSISTENT, AND GENETICALLY DIVERSE IN ZOO-HOUSED RED PANDAS (AILURUS FULGENS)
AMDOPARVOVIRUS INFECTIONS ARE PREVALENT, PERSISTENT, AND GENETICALLY DIVERSE IN ZOO-HOUSED RED PANDAS (AILURUS FULGENS) Open
Red pandas (Ailurus fulgens) are a globally endangered small carnivoran species and subjects of a robust ex situ conservation effort that includes animals housed in zoos. In 2018, red panda amdoparvovirus (RPAV) was discovered by metagenom…
View article: Viruses in unexplained encephalitis cases in American black bears (Ursus americanus)
Viruses in unexplained encephalitis cases in American black bears (Ursus americanus) Open
Viral infections were investigated in American black bears ( Ursus americanus ) from Nevada and northern California with and without idiopathic encephalitis. Metagenomics analyses of tissue pools revealed novel viruses in the genera Circov…
View article: Characterization of the histologic appearance of normal gill tissue using special staining techniques
Characterization of the histologic appearance of normal gill tissue using special staining techniques Open
Anatomic pathologists are familiar with stains used in light microscopy to identify cells, storage products, tissue deposits, and pathogens. Assessment of the surrounding tissue with special stains may reveal aspects of interest for the ti…
View article: Amdoparvovirus Infection in Red Pandas (<i>Ailurus fulgens</i>)
Amdoparvovirus Infection in Red Pandas (<i>Ailurus fulgens</i>) Open
Aleutian mink disease virus is the type species in the genus Amdoparvovirus, and in mink and other Mustelidae can cause either subclinical disease or fatal chronic immune stimulation and immune complex disease. The authors describe a novel…