Charles E. Davis
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View article: Foodborne <i>Listeria monocytogenes</i> Rhombencephalitis and Brainstem Abscess During a National Outbreak: Case Report and Literature Review
Foodborne <i>Listeria monocytogenes</i> Rhombencephalitis and Brainstem Abscess During a National Outbreak: Case Report and Literature Review Open
We report a rare case of Listeria monocytogenes rhombencephalitis with brainstem abscess in a previously healthy adult amid a nationwide outbreak linked to deli meat. The 56-year-old man exhibited rapid neurologic deterioration, requiring …
View article: Variability of CD4+ Cell Counts in HIV-1–Uninfected Volunteers Who Are Eligible for a Phase I HIV Vaccine Study
Variability of CD4+ Cell Counts in HIV-1–Uninfected Volunteers Who Are Eligible for a Phase I HIV Vaccine Study Open
Objective: Vaccines and biologics containing CD4 molecules or HIV-1 gp120 might induce antibodies targeting CD4. We evaluated temporal variability of CD4 levels in healthy volunteers to quantify declines that could indicate true adverse ev…
View article: 2838. Safety and Immunogenicity of a gp120-CD4 Chimeric Subunit Vaccine: A Phase 1a Randomized Controlled Trial
2838. Safety and Immunogenicity of a gp120-CD4 Chimeric Subunit Vaccine: A Phase 1a Randomized Controlled Trial Open
Background A primary challenge for HIV vaccine development is to raise antiviral antibodies capable of recognizing highly variable viral antigens. The full-length single chain (FLSC) gp120-CD4 chimeric protein was designed to present a hig…
View article: Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202
Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202 Open
AIDS Clinical Trial Group study A5202 (ClinicalTrials.gov identifier NCT00118898) was a phase 3b, randomized, partially blinded equivalence study of open-label atazanavir/ritonavir or efavirenz, plus either placebo-controlled tenofovir dis…
View article: Charles E. Davis Interview
Charles E. Davis Interview Open
Typed transcript of interview with Leonard Sackett concerning the Baldwin Land Company farms in Dickey County, and their management. Owned by George Baldwin, and later, his sons George B. and Charles F. Baldwin.
View article: Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice
Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice Open
Significance Most HIV antiretrovirals target viral proteins. Unfortunately, HIV mutates under drug pressure, which can lead to drug resistance. Targeting cellular proteins that HIV necessitates in its lifecycle may help overcome HIV drug r…