Charles G. Wright
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View article: Development and evaluation of the modiolar research array – multi-centre collaborative study in human temporal bones
Development and evaluation of the modiolar research array – multi-centre collaborative study in human temporal bones Open
The MRA is a novel, very thin perimodiolar prototype electrode array that has been developed using a systematic collaborative approach. The different evaluation techniques employed by the investigators contributed to the early identificati…
View article: Automatic identification of cochlear implant electrode arrays for post-operative assessment
Automatic identification of cochlear implant electrode arrays for post-operative assessment Open
Cochlear implantation is a procedure performed to treat profound hearing loss. Accurately determining the postoperative position of the implant in vivo would permit studying the correlations between implant position and hearing restoration…
View article: Anatomic verification of a novel method for precise intrascalar localization of cochlear implant electrodes in adult temporal bones using clinically available computed tomography
Anatomic verification of a novel method for precise intrascalar localization of cochlear implant electrodes in adult temporal bones using clinically available computed tomography Open
We have anatomically validated this automated method for predicting the intrascalar location of CI arrays using CT. Using this algorithm and pre- and postintervention CT, rapid feedback regarding implant location and expected audiologic ou…
View article: Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation
Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation Open
Usher syndrome 3A (USH3A) is an autosomal recessive disorder characterized by progressive loss of hearing and vision due to mutation in the clarin-1 (CLRN1) gene. Lack of an animal model has hindered our ability to understand the function …
View article: Development of Outer Hair Cells in Ames Waltzer Mice: Mutation in Protocadherin 15 Affects Development of Cuticular Plate and Associated Structures
Development of Outer Hair Cells in Ames Waltzer Mice: Mutation in Protocadherin 15 Affects Development of Cuticular Plate and Associated Structures Open
The Ames waltzer ( av ) mouse mutant harbors a mutation in the protocadherin 15 gene ( Pcdh15 ) and is a model for deafness in Usher syndrome 1F and nonsyndromic deafness DFNB23. Mutation in Pcdh15 affects stereocilia morphogenesis and pol…
View article: Cochlear Implant Electrode Insertion: The Round Window Revisited
Cochlear Implant Electrode Insertion: The Round Window Revisited Open
Objective: To examine aspects of round window (RW) anatomy that are relevant to its use as a portal for atraumatic insertion of cochlear implant electrodes. Study Design: Anatomic study using human cadaveric temporal bones. Methods: A seri…
View article: Particulate dermal matrix as an injectable soft tissue replacement material
Particulate dermal matrix as an injectable soft tissue replacement material Open
Products currently used as injectable soft tissue replacement materials in the dermatologic, plastic and reconstructive, and urological fields exhibit several shortfalls including reactivity, migration, rapid degradation, and necessity of …
View article: An Animal Model for External Ear Canal Inflammation
An Animal Model for External Ear Canal Inflammation Open
Objective To develop an animal model for testing efficacy of anti‐inflammatory drugs designed to treat external ear canal (EAC) disease. Methods Histological and morphometric methods were used to characterize EAC inflammation produced by t…
View article: A New Mouse Insertional Mutation That Causes Sensorineural Deafness and Vestibular Defects
A New Mouse Insertional Mutation That Causes Sensorineural Deafness and Vestibular Defects Open
This article describes a new recessive insertional mutation in the transgenic line TgN2742Rpw that causes deafness and circling behavior in mice. Histologic analysis revealed virtually complete loss of the cochlear neuroepithelium (the org…
View article: Insecticide Sprays, 1994
Insecticide Sprays, 1994 Open
Kitchens in single family dwellings located in Duplin and Sampson counties, NC served as test sites. Five kitchens with a minimum of 100 living German cockroaches sighted during a preliminary visual survey were assigned to each formulation…
View article: Insecticide Efficacy in German Cockroach Control, 1992
Insecticide Efficacy in German Cockroach Control, 1992 Open
Abamectin was applied into or near cracks and crevices with a Whitmire flowable dust applicator. Other forumulations were applied from self-pressurized, aerosol-type containers as pin-stream sprays into cracks and crevices. Single-family d…
View article: Efficacy of Insecticide Formulations, 1991
Efficacy of Insecticide Formulations, 1991 Open
Various self-pressurized sprays, supplied by Whitmire Research Laboratories (St. Louis, MO), were directed into cracks and crevices in kitchens within single-family dwellings located in Duplin, Johnston and Sampson counties, NC. Kitchens w…
View article: Incidence of Otitis Media in Vitamin A‐Deficient Guinea Pigs
Incidence of Otitis Media in Vitamin A‐Deficient Guinea Pigs Open
After observing an association between vitamin A deficiency and otitis media among children in Micronesia, we sought to develop an animal model for vitamin A‐deficiency‐induced otitis media. Thirty juvenile guinea pigs were screened for ab…
View article: Evaluation of Insecticides for Controlling German Cockroaches, 1990
Evaluation of Insecticides for Controlling German Cockroaches, 1990 Open
Pin-stream sprays from self-pressurized, aerosoltype containers, were directed into cracks and crevices of dwellings. Single-family dwellings, located in Sampson or Duplin counties, NC, served as test sites. Kitchens with a minimum of 100 …
View article: Efficacy of Insecticide Formulations, 1989
Efficacy of Insecticide Formulations, 1989 Open
Self-pressurized sprays, supplied by Whitmire Research Laboratories (St. Louis, MO), were directed into cracks and crevices in single-family dwellings, located in Wake, Johnston and Wayne counties, N.C. Kitchens with a minimum of 60 German…
View article: Evaluation of Insecticides for Controlling German Cockroaches, 1988
Evaluation of Insecticides for Controlling German Cockroaches, 1988 Open
Self-pressurized sprays were directed into cracks and crevices of dwellings using appropriate crack and crevice equipment. Microencapsulated chlorpyrifos was applied as a pinstream spot application from a 3.785 liter compressed air sprayer…
View article: Insecticide Evaluation, 1987
Insecticide Evaluation, 1987 Open
Field tests determined the relative effectiveness of self-pressurized sprays containing abamectin, microencap-sulated chlorpyrifos, chlorpyrifos + Dimilin, or chlorpyrifos + fenoxycarb; compressed-air sprays of acephate, acephate + deodora…
View article: Self-Pressurized, Encapsulated Sprays for German Cockroach Control in Single-Family Dwellings, 1985
Self-Pressurized, Encapsulated Sprays for German Cockroach Control in Single-Family Dwellings, 1985 Open
Field evaluations were made in single-family dwellings infested with at least 25 visible German cockroaches/kitchen to compare the efficacy of 6 self-pressurized, encapsulated insecticide formulations against a standard nonencapsulated chl…
View article: Evaluation of Potential Insecticides for Controlling German Cockroaches, 1986
Evaluation of Potential Insecticides for Controlling German Cockroaches, 1986 Open
Field tests were conducted to determine the relative effectiveness of self-pressurized sprays containing 1 of 2 concentrations of cyfluthrin or 1 concentration of an avermectins bait or dusttype baits of avermectins, boric acid, or fenoxyc…
View article: Performance of Baythroid for Reduction of Single-Comb Wasp Colonies, 1984
Performance of Baythroid for Reduction of Single-Comb Wasp Colonies, 1984 Open
Field tests were conducted to determine he relative efficiency of Baythroid compared to Orthene, which has a wasp control label, for single-comb wasp reduction. Adults of Polistes sp. resting on rests attached to buildings were tallied. Ne…
View article: Cypermethrin Sprays for German Cockroach Control in Single-Family Dwellings, 1986
Cypermethrin Sprays for German Cockroach Control in Single-Family Dwellings, 1986 Open
Field evaluations were conducted in single-family dwellings infested with at least 25 visible German cockroaches per kitchen to compare the efficacies of 2 concentrations of cypermethrin against a standard, chlorpyrifos. Visually-sighted G…
View article: COCKROACH SPECIES OBSERVED IN STRUCTURES ON A PERMANENT MILITARY BASE OVER A 20-YEAR PERIOD1
COCKROACH SPECIES OBSERVED IN STRUCTURES ON A PERMANENT MILITARY BASE OVER A 20-YEAR PERIOD1 Open
A 20-year, monthly tally of cockroaches in structures at Fort Bragg, NC, a permanent military base, showed German cockroaches the most prevalent, with American, oriental, brownbanded, and smokybrown cockroaches also present. During the 20 …
View article: Ototoxicity of low- and moderate-dose cisplatin
Ototoxicity of low- and moderate-dose cisplatin Open
Twenty-four patients with head and neck neoplasms were prospectively evaluated for cisplatin (DDP)-induced ototoxicity. Patients were selected from a larger population based on the uniformity of their chemotherapy regimen, renal status, la…