Charles J. Prestigiacomo
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View article: 531 Novel inflammatory gene expression changes occur within the occluded vasculature of large vessel ischemic stroke
531 Novel inflammatory gene expression changes occur within the occluded vasculature of large vessel ischemic stroke Open
Objectives/Goals: We hypothesized that the bulk transcriptomic profiling of blood collected from within the ischemic vasculature during an acute ischemic stroke with large vessel occlusion (LVO) will contain unique biomarkers that are diff…
View article: A standalone minimally invasive presigmoid retrolabyrinthine suprameatal approach: A cadaveric morphometric study
A standalone minimally invasive presigmoid retrolabyrinthine suprameatal approach: A cadaveric morphometric study Open
Background Presigmoid approaches provide access to several structures anterior to the sigmoid sinus (SS) and may be intended for the treatment of lesions located in the middle and posterior fossa. We conducted a morphometric cadaveric stud…
View article: Inter-modality correlation across invasive and noninvasive angiography in the three-dimensional assessment of cerebral aneurysms
Inter-modality correlation across invasive and noninvasive angiography in the three-dimensional assessment of cerebral aneurysms Open
Background: Non-invasive and invasive methods of cerebral angiography, including computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA), are commonly used to characterize and …
View article: Using clinical and radiographic variables to predict intracranial aneurysm rupture status with machine learning.
Using clinical and radiographic variables to predict intracranial aneurysm rupture status with machine learning. Open
Among the models, RF achieved the highest accuracy (85%) with balanced precision and recall. Across models 3D geometric features drove model performance, highlighting the importance of these features in predicting rupture status.
View article: Targeted palliative endovascular embolization of a glomus jugulotympanicum tumor for refractory Jacobson’s neuralgia: A case report
Targeted palliative endovascular embolization of a glomus jugulotympanicum tumor for refractory Jacobson’s neuralgia: A case report Open
Background: Glomus tumors around the jugular foramen and inner ear can have variable presentations, including lower cranial nerve palsies, tinnitus, hearing loss, or palpable neck mass. In general, these tumors are benign paragangliomas wi…
View article: Using fractal dimension to predict the risk of intra cranial aneurysm rupture with machine learning
Using fractal dimension to predict the risk of intra cranial aneurysm rupture with machine learning Open
Intracranial aneurysms (IAs) that rupture result in significant morbidity and mortality. While traditional risk models such as the PHASES score are useful in clinical decision making, machine learning (ML) models offer the potential to pro…
View article: Tumor Embolic Stroke: The Importance of Pathological Assessment of Clots after Thrombectomy
Tumor Embolic Stroke: The Importance of Pathological Assessment of Clots after Thrombectomy Open
While tumor emboli are a rare cause of stroke in cancer patients, they highlight the importance of gross observations and pathological assessments in the evaluation of clots. In this case report, a 70-year-old male with type 2 diabetes mel…
View article: Genetics of ischemic stroke functional outcome
Genetics of ischemic stroke functional outcome Open
Ischemic stroke, which accounts for 87% of cerebrovascular accidents, is responsible for massive global burden both in terms of economic cost and personal hardship. Many stroke survivors face long-term disability—a phenotype associated wit…
View article: Cortical incisions and transcortical approaches for intra-axial and intraventricular lesions: A scoping review
Cortical incisions and transcortical approaches for intra-axial and intraventricular lesions: A scoping review Open
Background: Transcortical approaches, encompassing various surgical corridors, have been employed to treat an array of intraparenchymal or intraventricular brain pathologies, including tumors, vascular malformations, infections, intracereb…
View article: Factors Affecting Selection of TraineE for Neurointervention (FASTEN)
Factors Affecting Selection of TraineE for Neurointervention (FASTEN) Open
Background and importance Neurointervention is a very competitive specialty in the United States due to the limited number of training spots and the larger pool of applicants. The training standards are continuously updated to ensure solid…
View article: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome
Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome Open
View article: Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome
Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome Open
Introduction Background: Thrombectomy improves outcomes in patients with basilar artery (BA) occlusion [1,2]. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T‐ or Y‐shaped, may impact the outcome. Spec…
View article: Post-traumatic Middle Meningeal Artery Pseudoaneurysm Treated With Endovascular Coil Embolization
Post-traumatic Middle Meningeal Artery Pseudoaneurysm Treated With Endovascular Coil Embolization Open
View article: Blood Pressure Management After Endovascular Therapy for Acute Ischemic Stroke
Blood Pressure Management After Endovascular Therapy for Acute Ischemic Stroke Open
Importance The effects of moderate systolic blood pressure (SBP) lowering after successful recanalization with endovascular therapy for acute ischemic stroke are uncertain. Objective To determine the futility of lower SBP targets after end…
View article: Basilar artery recanalization by proximal balloon occlusion and aspiration in a single vessel vertebrobasilar system: A case report
Basilar artery recanalization by proximal balloon occlusion and aspiration in a single vessel vertebrobasilar system: A case report Open
The authors present a case of a patient with a hypoplastic right vertebral artery (VA) ending in the posterior inferior cerebellar artery who sustained an acute onset basilar artery occlusion. A balloon-guided catheter was used to proximal…
View article: Introduction. On forging a new specialty from the crucible of war
Introduction. On forging a new specialty from the crucible of war Open
Over the course of history, human conflict has been responsible for immeasurable loss of life.Care for the wounded evolved desultorily during this time, and though many believe that war has accelerated medical and surgical progress to the …
View article: The history of antibiotic irrigation and prophylaxis in operative neurotrauma: perpetuation of military care in civilian settings
The history of antibiotic irrigation and prophylaxis in operative neurotrauma: perpetuation of military care in civilian settings Open
The benefit of antibiotic irrigation for prophylaxis against wound infections, not only for traumatic cranial injuries but also in elective neurosurgical care, has recently been called into question. Several articles have cast doubt on the…
View article: Differences in Automated Perfusion Software: Do They Matter Clinically?
Differences in Automated Perfusion Software: Do They Matter Clinically? Open
View article: Design of the BEST‐II Randomized Clinical Trial
Design of the BEST‐II Randomized Clinical Trial Open
Background Prior observational studies indicate that lower systolic blood pressure (SBP) after successful endovascular treatment (EVT) is associated with better functional outcomes in patients with acute ischemic stroke. However, whether t…
View article: Endovascular treatment in the multimodality management of brain arteriovenous malformations: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee
Endovascular treatment in the multimodality management of brain arteriovenous malformations: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee Open
Background The purpose of this review is to summarize the data available for the role of angiography and embolization in the comprehensive multidisciplinary management of brain arteriovenous malformations (AVMs Methods We performed a struc…
View article: An algorithm to improve lateralization accuracy of inferior petrosal sinus sampling: procedural nuances for complex patterns of venous drainage. Patient series
An algorithm to improve lateralization accuracy of inferior petrosal sinus sampling: procedural nuances for complex patterns of venous drainage. Patient series Open
BACKGROUND Inferior petrosal sinus sampling (IPSS) is a useful technique in the diagnosis of Cushing’s disease (CD) when the imaging finding is negative or equivocal. Different authors have reported considerable variability in the ability …
View article: Editorial. Myths, misquotes, and the perpetuation of errors through the published literature: the double-edged sword of progress
Editorial. Myths, misquotes, and the perpetuation of errors through the published literature: the double-edged sword of progress Open
"Editorial. Myths, misquotes, and the perpetuation of errors through the published literature: the double-edged sword of progress" published on 14 May 2021 by American Association of Neurological Surgeons.
View article: Social media usage for neurointerventionalists: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee
Social media usage for neurointerventionalists: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee Open
The purpose of this publication is to provide a review of social media usage by neurointerventionalists. Using published literature and available local, regional, and national guidelines or laws, we reviewed data on social media usage as i…
View article: The surgical history of head injury in motor vehicle collision
The surgical history of head injury in motor vehicle collision Open
Motor vehicle collisions (MVCs) are a significant cause of head injuries today, but efforts to manage and prevent these injuries extend as far back as the beginning of modern neurosurgery itself. Head trauma in MVCs occurred as far back as…
View article: Blunt cerebrovascular injury in the geriatric population
Blunt cerebrovascular injury in the geriatric population Open
OBJECTIVE Blunt cerebrovascular injury (BCVI) is associated with high rates of neurological morbidity and mortality. The detection and management of BCVI has improved with advances in imaging and sensitive screening protocols. Few studies …
View article: E-238 Relative angle of deflection correlates with aneurysmal rupture status in posterior communicating artery aneurysms
E-238 Relative angle of deflection correlates with aneurysmal rupture status in posterior communicating artery aneurysms Open
Background The ability to prognosticate rupture for cerebral aneurysms is paramount to prevent the risks inherent to open clipping or endovascular coiling. The goal of this study was to create a mathematical model to predict the probabilit…
View article: Effect of COVID-19 on Emergent Stroke Care
Effect of COVID-19 on Emergent Stroke Care Open
Background and Purpose: Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mor…
View article: Endovascular Therapy for Patients With Acute Ischemic Stroke During the COVID-19 Pandemic: A Proposed Algorithm
Endovascular Therapy for Patients With Acute Ischemic Stroke During the COVID-19 Pandemic: A Proposed Algorithm Open
emergent stroke team contact, and emergent initiation of EVT in eligible patients
View article: The history of the Journal of Neurosurgery: how the “White Journal” helped in the growth of neurological surgery
The history of the Journal of Neurosurgery: how the “White Journal” helped in the growth of neurological surgery Open
As the Journal of Neurosurgery ( JNS ) enters its 76th year of publication, its role as a principal repository of the neurosurgical body of knowledge continues to rise. Following in the steps of earlier journals in other disciplines, the J…
View article: Shear stress and aneurysms: a review
Shear stress and aneurysms: a review Open
Wall shear stress, the frictional force of blood flow tangential to an artery lumen, has been demonstrated in multiple studies to influence aneurysm formation and risk of rupture. In this article, the authors review the ways in which shear…