Charlotte Butterworth
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View article: KDM5-driven transcriptional noise fuels plasticity-led awakening and relapse in paediatric cancer
KDM5-driven transcriptional noise fuels plasticity-led awakening and relapse in paediatric cancer Open
How drug-tolerant persister (DTP) cells escape quiescence to drive tumour relapse is a central unresolved question in cancer evolution. Here, we identify transcriptional noise (TN), defined as the stochastic variability in gene expression,…
View article: Supplementary Table 2 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 2 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 2
View article: Supplementary Table 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 1
View article: Supplementary Table Legend 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table Legend 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table Legend
View article: Supplementary Table 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 1
View article: Supplementary Table 3 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 3 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 3
View article: Supplementary Table Legend 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table Legend 1 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table Legend
View article: Supplementary Table 4 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 4 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 4
View article: Supplementary Table 3 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 3 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 3
View article: Supplementary Table 2 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 2 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 2
View article: SupplemetaryFigure1-5 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
SupplemetaryFigure1-5 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
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View article: SupplemetaryFigure1-5 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
SupplemetaryFigure1-5 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
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View article: Data from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Data from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Purpose:The study of cell-free DNA (cfDNA) enables sequential analysis of tumor cell–specific genetic alterations in patients with neuroblastoma.Experimental Design:Eighteen patients with relapsing neuroblastoma having received lorlatinib,…
View article: Supplementary Table 4 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Supplementary Table 4 from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Supplementary Table 4
View article: Data from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy
Data from Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i>-Targeted Therapy Open
Purpose:The study of cell-free DNA (cfDNA) enables sequential analysis of tumor cell–specific genetic alterations in patients with neuroblastoma.Experimental Design:Eighteen patients with relapsing neuroblastoma having received lorlatinib,…
View article: Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i> -Targeted Therapy
Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving <i>ALK</i> -Targeted Therapy Open
Purpose: The study of cell-free DNA (cfDNA) enables sequential analysis of tumor cell–specific genetic alterations in patients with neuroblastoma. Experimental Design: Eighteen patients with relapsing neuroblastoma having received lorlatin…
View article: Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis
Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis Open
Recent studies have shown that the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and responsiveness to immunotherapy. A question that remains unresolved is wh…