Charlotte Simms
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View article: Determination of the Experimental Minimal Formula of Metal‐Organic Frameworks
Determination of the Experimental Minimal Formula of Metal‐Organic Frameworks Open
The determination of the precise chemical composition of metal organic frameworks (MOFs) is often overlooked, although it is crucial for many advanced applications such as catalysis or drug delivery. Here, a rigorous yet simple method is p…
View article: Determination of the experimental minimal formula of metal-organic frameworks
Determination of the experimental minimal formula of metal-organic frameworks Open
Metal-organic frameworks have emerged as one of the most promising classes of materials in the last decade with potential applications in many domains of science. However, the determination of their precise chemical composition has often b…
View article: Determination of the experimental minimal formula of metal-organic frameworks
Determination of the experimental minimal formula of metal-organic frameworks Open
Metal-organic frameworks have emerged as one of the most promising classes of materials in the last decade with potential applications in many domains of science. However, the determination of their precise chemical composition has been of…
View article: The Central Role of Oxo Clusters in Zirconium‐Based Esterification Catalysis
The Central Role of Oxo Clusters in Zirconium‐Based Esterification Catalysis Open
Oxo clusters are a unique link between oxide nanocrystals and Metal‐Organic Frameworks (MOFs), representing the limit of downscaling each of the respective crystals. Herein, the superior catalytic activity of clusters, compared to zirconiu…
View article: The central role of oxo clusters in zirconium- and hafnium-based esterification catalysis.
The central role of oxo clusters in zirconium- and hafnium-based esterification catalysis. Open
Oxo clusters are a unique link between oxide nanocrystals and MOFs, representing the limit of downscaling each of the respective crystals. Here, we show the superior catalytic activity of Zr12O8(OH)8(OOCR)24 clusters, compared to zirconium…
View article: Green, Safe, and Reliable Synthesis of Bimetallic MOF‐808 Nanozymes With Enhanced Aqueous Stability and Reactivity for Biological Applications
Green, Safe, and Reliable Synthesis of Bimetallic MOF‐808 Nanozymes With Enhanced Aqueous Stability and Reactivity for Biological Applications Open
Bimetallic metal‐organic frameworks (MOFs) are promising nanomaterials whose reactivity towards biomolecules remains challenging due to issues related to synthesis, stability, control over metal oxidation state, phase purity, and atomic le…
View article: Highly defective ultra-small tetravalent MOF nanocrystals
Highly defective ultra-small tetravalent MOF nanocrystals Open
The size and defects in crystalline inorganic materials are of importance in many applications, particularly catalysis, as it often results in enhanced/emerging properties. So far, applying the modulation chemistry strategy has been unable…
View article: Highly defective ultra-small M(IV)-MOF nanocrystals
Highly defective ultra-small M(IV)-MOF nanocrystals Open
A precise and concomitant control of both the size and defects in inorganic materials is of importance in many applications, particularly catalysis, as it often results in enhanced properties or emerging new features. So far, applying the …
View article: In vivo toxicity evaluation of a polyoxotungstate nanocluster as a promising contrast agent for computed tomography
In vivo toxicity evaluation of a polyoxotungstate nanocluster as a promising contrast agent for computed tomography Open
In this study, we demonstrate for the first time, that a discrete metal-oxo cluster α-/β-K 6 P 2 W 18 O 62 (WD-POM) exhibits superior performance as a computed tomography (CT) contrast agent, in comparison to the standard contrast agent io…
View article: In vivo toxicity evaluation of a polyoxotungstate nanocluster as a promising contrast agent for computed tomography
In vivo toxicity evaluation of a polyoxotungstate nanocluster as a promising contrast agent for computed tomography Open
In this study, we demonstrate for the first time, that a discrete metal-oxo cluster α-/β-K 6 P 2 W 18 O 62 (WD-POM) exhibits superior performance as a computed tomography (CT) contrast agent, in comparison to the standard contrast agent io…
View article: MOF catalysis meets biochemistry: molecular insights from the hydrolytic activity of MOFs towards biomolecules
MOF catalysis meets biochemistry: molecular insights from the hydrolytic activity of MOFs towards biomolecules Open
The versatility of metal–organic frameworks (MOF) towards hydrolysis of a range of biological molecules is explored in detail to underline specific challenges and exciting possibilities of developing MOFs as nanozymes.
View article: Front Cover: Understanding the Role of Surfactants in the Interaction and Hydrolysis of Myoglobin by Zr‐MOF‐808 (Eur. J. Inorg. Chem. 20/2022)
Front Cover: Understanding the Role of Surfactants in the Interaction and Hydrolysis of Myoglobin by Zr‐MOF‐808 (Eur. J. Inorg. Chem. 20/2022) Open
The Front Cover shows the interaction of myoglobin protein, represented by a bee, with Zr-MOF-808, represented by the honeycomb structure. In nature the relation between a bee and a honeycomb is a favorable interaction, and the same can be…
View article: Understanding the Role of Surfactants in the Interaction and Hydrolysis of Myoglobin by Zr‐MOF‐808
Understanding the Role of Surfactants in the Interaction and Hydrolysis of Myoglobin by Zr‐MOF‐808 Open
Controlled protein hydrolysis is an important procedure in proteomics applications and is used to aid the understanding of protein structure and function. The hydrolysis of hydrophobic proteins is particularly challenging, as due to their …
View article: Enhancing the Catalytic Activity of MOF‐808 Towards Peptide Bond Hydrolysis through Synthetic Modulations
Enhancing the Catalytic Activity of MOF‐808 Towards Peptide Bond Hydrolysis through Synthetic Modulations Open
The performance of MOFs in catalysis is largely derived from structural features, and much work has focused on introducing structural changes such as defects or ligand functionalisation to boost the reactivity of the MOF. However, the effe…
View article: Monodispersed MOF-808 Nanocrystals Synthesized via a Scalable Room-Temperature Approach for Efficient Heterogeneous Peptide Bond Hydrolysis
Monodispersed MOF-808 Nanocrystals Synthesized via a Scalable Room-Temperature Approach for Efficient Heterogeneous Peptide Bond Hydrolysis Open
International audience
View article: Bimetallic Ce/Zr UiO-66 Metal–Organic Framework Nanostructures as Peptidase and Oxidase Nanozymes
Bimetallic Ce/Zr UiO-66 Metal–Organic Framework Nanostructures as Peptidase and Oxidase Nanozymes Open
sponsorship: A.L. thanks the FWO Flanders (Belgium) for the doctoral fellowship 48730/1S10318N. C.S. thanks the FWO Flanders (Belgium) for the doctoral fellowship 68090/11C9320N. T.P.V. and D.D.V. thank the FWO Flanders (Belgium) for fundi…
View article: Heterogeneous nanozymatic activity of Hf oxo-clusters embedded in a metal–organic framework towards peptide bond hydrolysis
Heterogeneous nanozymatic activity of Hf oxo-clusters embedded in a metal–organic framework towards peptide bond hydrolysis Open
A Hf-based NU-1000 metal organic framework as a hydrolytic nanozyme for peptide bonds in dipeptides and hen egg white lysozyme protein showed greater stability and better recyclability than previous Zr-/Hf-based nanozymes.
View article: Front Cover: Metal‐Addenda Substitution in Plenary Polyoxometalates and in their Modular Transition Metal Analogues (Eur. J. Inorg. Chem. 27/2020)
Front Cover: Metal‐Addenda Substitution in Plenary Polyoxometalates and in their Modular Transition Metal Analogues (Eur. J. Inorg. Chem. 27/2020) Open
The Front Cover shows a selection of mixed-addenda polyoxometalate structures, along with a hexametalate analogue used in the construction of metal organic frameworks. Isomerism of these mixed-metal molecular metal oxides is highly complex…
View article: Metal‐Addenda Substitution in Plenary Polyoxometalates and in Their Modular Transition Metal Analogues
Metal‐Addenda Substitution in Plenary Polyoxometalates and in Their Modular Transition Metal Analogues Open
For decades, the formal metal addenda substitution in the matrix of bulk metal oxides has been a prolific strategy to develop numerous (non‐)stoichiometric all‐inorganic compounds with tunable electronic and magnetic properties, and broad …
View article: Interplay between structural parameters and reactivity of Zr<sub>6</sub>-based MOFs as artificial proteases
Interplay between structural parameters and reactivity of Zr<sub>6</sub>-based MOFs as artificial proteases Open
Peptide bond hydrolysis catalyzed by NU-1000 MOF revealed key structural features that influence the catalytic performance of Zr6based MOFs.