Charo I. del Genio
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View article: Equitability and explosive synchronisation in multiplex and higher-order networks
Equitability and explosive synchronisation in multiplex and higher-order networks Open
Cluster synchronisation is a key phenomenon observed in networks of coupled dynamical units. Its presence has been linked to symmetry and, more generally, to equability of the underlying network pattern of interactions between identical dy…
View article: Equitability and explosive synchronisation in multiplex and higher-order networks
Equitability and explosive synchronisation in multiplex and higher-order networks Open
Cluster synchronisation is a key phenomenon observed in networks of coupled dynamical units. Its presence has been linked to symmetry and, more generally, to equability of the underlying network pattern of interactions between identical dy…
View article: Hypermodularity and community detection in hypergraphs
Hypermodularity and community detection in hypergraphs Open
Numerous networked systems feature a structure of nontrivial communities, which often correspond to their functional modules. Such communities have been detected in real-world biological, social, and technological systems, as well as in sy…
View article: Reconstructing simplicial complexes from evolutionary games
Reconstructing simplicial complexes from evolutionary games Open
In distributed systems, knowledge of the network structure of the connections among the unitary components is often a requirement for an accurate prediction of the emerging collective dynamics. However, in many real-world situations, one h…
View article: Flexible mitigation of epidemics by transport management
Flexible mitigation of epidemics by transport management Open
View article: Multi-dimensional multi-option opinion dynamics leads to the emergence of clusters in social networks
Multi-dimensional multi-option opinion dynamics leads to the emergence of clusters in social networks Open
View article: Hypermodularity and community detection in higher-order networks
Hypermodularity and community detection in higher-order networks Open
Numerous networked systems feature a structure of non-trivial communities, which often correspond to their functional modules. Such communities have been detected in real-world biological, social and technological systems, as well as in sy…
View article: Periodic systems have new classes of synchronization stability
Periodic systems have new classes of synchronization stability Open
The master stability function is a robust and useful tool for determining the conditions of synchronization stability in a network of coupled systems. While a comprehensive classification exists in the case in which the nodes are chaotic d…
View article: Periodic systems have new classes of synchronization stability
Periodic systems have new classes of synchronization stability Open
The Master Stability Function is a robust and useful tool for determining the conditions of synchronization stability in a network of coupled systems. While a comprehensive classification exists in the case in which the nodes are chaotic d…
View article: Intrinsic disorder and conformational coexistence in auxin coreceptors
Intrinsic disorder and conformational coexistence in auxin coreceptors Open
AUXIN/INDOLE 3-ACETIC ACID (Aux/IAA) transcriptional repressor proteins and the TRANSPORT INHIBITOR RESISTANT 1/AUXIN SIGNALING F-BOX (TIR1/AFB) proteins to which they bind act as auxin coreceptors. While the structure of TIR1 has been sol…
View article: The structure and dynamics of networks with higher order interactions
The structure and dynamics of networks with higher order interactions Open
View article: Non‐specific effects of the <scp>CINNAMATE‐4‐HYDROXYLASE</scp> inhibitor piperonylic acid
Non‐specific effects of the <span>CINNAMATE‐4‐HYDROXYLASE</span> inhibitor piperonylic acid Open
SUMMARY Chemical inhibitors are often implemented for the functional characterization of genes to overcome the limitations associated with genetic approaches. Although it is well established that the specificity of the compound is key to s…
View article: A case study of the Ancientbiotics collaboration
A case study of the Ancientbiotics collaboration Open
View article: Mean-field nature of synchronization stability in networks with multiple interaction layers
Mean-field nature of synchronization stability in networks with multiple interaction layers Open
View article: Mean-field nature of synchronization stability in networks with multiple interaction layers
Mean-field nature of synchronization stability in networks with multiple interaction layers Open
The interactions between the components of many real-world systems are best modelled by networks with multiple layers. Different theories have been proposed to explain how multilayered connections affect the linear stability of synchroniza…
View article: Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis
Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis Open
Chemical inhibitors are often implemented for the functional characterization of genes to overcome the limitations associated with genetic approaches. Although being a powerful tool, off-target effects of these inhibitors are easily overlo…
View article: Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane
Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane Open
View article: A transposon surveillance mechanism that safeguards plant male fertility during stress
A transposon surveillance mechanism that safeguards plant male fertility during stress Open
Although plants are able to withstand a range of environmental conditions, spikes in ambient temperature can impact plant fertility causing reductions in seed yield and significant economic losses 1,2 . Therefore, understanding the precise…
View article: Structure-based modelling and dynamics of MurM, a<i>Streptococcus pneumoniae</i>penicillin resistance determinant that functions at the cytoplasmic membrane interface
Structure-based modelling and dynamics of MurM, a<i>Streptococcus pneumoniae</i>penicillin resistance determinant that functions at the cytoplasmic membrane interface Open
MurM is an aminoacyl-tRNA dependant ligase that aminoacylates the Lipid II peptidoglycan precursor, in the human pathogen Streptococcus pneumoniae . MurM is required for the generation of branched peptidoglycan precursors enabling indirect…
View article: Data Mining a Medieval Medical Text Reveals Patterns in Ingredient Choice That Reflect Biological Activity against Infectious Agents
Data Mining a Medieval Medical Text Reveals Patterns in Ingredient Choice That Reflect Biological Activity against Infectious Agents Open
We used established methodologies from network science to identify patterns in medicinal ingredient combinations in a key medieval text, the 15th-century Lylye of Medicynes , focusing on recipes for topical treatments for symptoms of micro…
View article: Structure-Based Modelling and Dynamics of MurM, a Streptococcus Pneumoniae Penicillin Resistance Determinant that Functions at the Cytoplasmic Membrane Interface
Structure-Based Modelling and Dynamics of MurM, a Streptococcus Pneumoniae Penicillin Resistance Determinant that Functions at the Cytoplasmic Membrane Interface Open
View article: The Tetrazole Analogue of the Auxin Indole-3-acetic Acid Binds Preferentially to TIR1 and Not AFB5
The Tetrazole Analogue of the Auxin Indole-3-acetic Acid Binds Preferentially to TIR1 and Not AFB5 Open
Indole-3-acetic acid (auxin) is considered one of the cardinal hormones in plant growth and development. It regulates a wide range of processes throughout the plant. Synthetic auxins exploit the auxin-signaling pathway and are valuable as …
View article: Datamining a medieval medical text reveals patterns in ingredient choice\n that reflect biological activity against the causative agents of specified\n infections
Datamining a medieval medical text reveals patterns in ingredient choice\n that reflect biological activity against the causative agents of specified\n infections Open
The pharmacopeia used by physicians and lay people in medieval Europe has\nlargely been dismissed as placebo or superstition. While we now recognise that\nsome of the materia medica used by medieval physicians could have had useful\nbiolog…
View article: Datamining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against the causative agents of specified infections
Datamining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against the causative agents of specified infections Open
The pharmacopeia used by physicians and lay people in medieval Europe has largely been dismissed as placebo or superstition. While we now recognise that some of the materia medica used by medieval physicians could have had useful biologica…
View article: Datamining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against the causative agents of specified infections
Datamining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against the causative agents of specified infections Open
The pharmacopeia used by physicians and lay people in medieval Europe has largely been dismissed as placebo or superstition. While we now recognise that some of the materia medica used by medieval physicians could have had useful biologica…
View article: Evolutionary Conserved Cysteines Function as cis-Acting Regulators of Arabidopsis PIN-FORMED 2 Distribution
Evolutionary Conserved Cysteines Function as cis-Acting Regulators of Arabidopsis PIN-FORMED 2 Distribution Open
Coordination of plant development requires modulation of growth responses that are under control of the phytohormone auxin. PIN-FORMED plasma membrane proteins, involved in intercellular transport of the growth regulator, are key to the tr…
View article: Analysis of the communities of an urban mobile phone network
Analysis of the communities of an urban mobile phone network Open
Being able to characterise the patterns of communications between individuals across different time scales is of great importance in understanding people's social interactions. Here, we present a detailed analysis of the community structur…
View article: Finding network communities using modularity density
Finding network communities using modularity density Open
Many real-world complex networks exhibit a community structure, in which the modules correspond to actual functional units. Identifying these communities is a key challenge for scientists. A common approach is to search for the network par…
View article: Synchronization in networks with multiple interaction layers
Synchronization in networks with multiple interaction layers Open
When the coexistence of multiple types of interactions truly matters for the synchronization of interacting complex systems.
View article: Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity
Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity Open
We study the binding of plant hormone IAA on its receptor TIR1 introducing a novel computa-tional method that we call tomographic docking and that accounts for interactions occurring along the depth of the binding pocket. Our results sugge…