Châu Văn Minh
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View article: Chiết tách, tinh chế và thiết lập chất chuẩn từ một số hợp chất đặc trưng của dược liệu
Chiết tách, tinh chế và thiết lập chất chuẩn từ một số hợp chất đặc trưng của dược liệu Open
Khai thác tài nguyên thực vật và tri thức bản địa về dược liệu là chiến lược quan trọng trong nghiên cứu và phát triển thuốc mới tại Việt Nam. Chất chuẩn đối chiếu hóa học gọi tắt là chất chuẩn hay chất đối chiếu (chemical reference standa…
View article: Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular Dynamics
Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular Dynamics Open
Soluble epoxide hydrolase (sEH) is essential for converting epoxy fatty acids, such as epoxyeicosatrienoic acids (EETs), into their dihydroxy forms. EETs play a crucial role in regulating blood pressure, mediating anti-inflammatory respons…
View article: Sulfated Naphthopyrones and Anthraquinones from the Vietnamese Crinoid <i>Comanthus delicata</i>
Sulfated Naphthopyrones and Anthraquinones from the Vietnamese Crinoid <i>Comanthus delicata</i> Open
Three new sulfated naphthopyrone derivatives namely delicapyrons F-H (1-3) and two new sulfated anthraquinone derivatives namely delicaquinons A (4) and B (5), together with 6-methoxycomaparvin-5-methylether-8-O-sodium sulfate (6), 6-metho…
View article: Study on biological characteristics and biomass production of the green microalgae (Nannochloris atomus) isolated from Vietnam for the extraction of bioactive compounds
Study on biological characteristics and biomass production of the green microalgae (Nannochloris atomus) isolated from Vietnam for the extraction of bioactive compounds Open
Microalgae are known to be a nutrient-rich feed source for many aquatic animals. It is also an important raw material source to exploit high biological activity substances for humans. This is the first study on biological characteristics a…
View article: Anti‐inflammatory metabolites from a marine sponge‐associated fungus <i>Aspergillus</i> sp. <scp>IMBC‐FP2</scp>.05
Anti‐inflammatory metabolites from a marine sponge‐associated fungus <i>Aspergillus</i> sp. <span>IMBC‐FP2</span>.05 Open
Chemical investigation of the marine sponge‐derived fungal strain Aspergillus sp. IMBC‐FP2.05 resulted in isolation of five compounds, including JBIR‐74 ( 1 ), homogentisic acid ( 2 ), methyl (2,5‐dihydroxyphenyl)acetate ( 3 ), 3‐chloro‐2,…
View article: Terpene and lignan glycosides from the leaves of <i>Aralia chinensis</i>
Terpene and lignan glycosides from the leaves of <i>Aralia chinensis</i> Open
From the methanol extract of Aralia chinensis leaves, three terpene glycosides ( 1 ‐ 3 ) and one lignan glycoside (4) were isolated by using various chromatographic methods. Their chemical structures were identified as (2 R, 6 S )‐borane‐2…
View article: Secondary metabolites from a marine sponge‐associated fungus <i>Xenomyrothecium</i> sp. <scp>IMBC‐FP2</scp>.11
Secondary metabolites from a marine sponge‐associated fungus <i>Xenomyrothecium</i> sp. <span>IMBC‐FP2</span>.11 Open
In the study, seven compounds were isolated from an EtOAc extract of the marine‐derived fungal strain Xenomyrothecium sp. IMBC‐FP2.11, including (3 R ,4 R )‐4‐hydroxymellein ( 1 ), (3 R ,4 S )‐4‐hydroxymellein ( 2 ), trans ‐3,4‐dihydro‐3,4…
View article: The anticancer activities of stichoposide D isolated from the sea cucumber Stichopus chloronotus on NTERA-2 cancer stem cells
The anticancer activities of stichoposide D isolated from the sea cucumber Stichopus chloronotus on NTERA-2 cancer stem cells Open
As reported, cancer stem cells (CSCs) are in charge of dangerous characteristics including drug resistance, metastasis, recurrence and therapeutic effectiveness. Therefore, CSCs are an important target for discovering of novel effective an…
View article: Flavone C-glycosides from the leaves of Amesiodendron chinense
Flavone C-glycosides from the leaves of Amesiodendron chinense Open
View article: Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1
Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1 Open
Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including human prostate cancer and oral squamous cell carcinomas. ANO1 plays a critical role in tumor growth and maintenance of these…
View article: Araliachinoside A: A New Triterpene Glycoside From <i>Aralia chinensis</i> Leaves
Araliachinoside A: A New Triterpene Glycoside From <i>Aralia chinensis</i> Leaves Open
From the leaves of Aralia chinensis, 3 oleanane-type triterpene glycosides have been isolated, including 1 new glycoside, 3β,23 -dihydroxyolean-12-ene-28-oic acid 3 -O-β-d-glucopyranosyl-(1→3)- α-l-arabinopyranosyl-(1→3)-β-d-glucuronopyran…
View article: Araliaarmoside: A New Triterpene Glycoside Isolated From the Leaves of <i>Aralia armata</i>
Araliaarmoside: A New Triterpene Glycoside Isolated From the Leaves of <i>Aralia armata</i> Open
One new oleanane-type triterpene glycoside, oleanolic acid-[28 -O-β-d-glucopyranosyl]-3 -O-[ β-d-glucopyranosyl(1→6)- β-d-glucopyranosyl](1→3)[ α-l-arabinofuranosyl(1→4)]- β-d-glucuronopyranoside (1), and 3 known ones {oleanolic acid-[28 -…
View article: Author response for "Structure elucidation of two new diterpenes from Vietnamese mangrove Ceriops decandra"
Author response for "Structure elucidation of two new diterpenes from Vietnamese mangrove Ceriops decandra" Open
View article: Isolation, screening antimicrobial activity and identification of fungi from marine sediments of the area Thanh Lan, Co To, Vietnam
Isolation, screening antimicrobial activity and identification of fungi from marine sediments of the area Thanh Lan, Co To, Vietnam Open
Marine environment is rich in natural product resources, including marine microorganisms, especially fungi which are not only seen as a potential source of highly applicable bioactive substances but also can provide for science new chemica…
View article: Limonoids From <i>Choerospondias axillaris</i>
Limonoids From <i>Choerospondias axillaris</i> Open
Eight limonoids (1-8), including 1 new compound named as axillariol A (1), were isolated from the dichloromethane extract of Choerospondias axillaris branches and leaves using various chromatographic separations. Their structures were conf…
View article: Screening and identification of actinomycetes having antimicrobial activity isolated from marine organisms and sediment samples in Ly Son island, Quang Ngai
Screening and identification of actinomycetes having antimicrobial activity isolated from marine organisms and sediment samples in Ly Son island, Quang Ngai Open
The discovery of bioactive compounds from marine microorganisms for drug development has been currently widely studied. In which marine actinomycetes are highlighted as a potential source in finding antibiotics as well as substances with b…
View article: Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities
Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities Open
Gymnema sylvestre, a medicinal plant, has been used in Indian ayurvedic traditional medicine for the treatment of diabetes. Phytochemical investigation of Gymnema sylvestre led to the isolation of five new pregnane glycosides, gymsylosides…
View article: Author response for "Structure elucidation of two new diterpenes from Vietnamese mangrove Ceriops decandra"
Author response for "Structure elucidation of two new diterpenes from Vietnamese mangrove Ceriops decandra" Open
View article: Diterpenoids and Flavonoids from <i>Andrographis paniculata</i>
Diterpenoids and Flavonoids from <i>Andrographis paniculata</i> Open
Chemical investigation of the aerial parts of Andrographis paniculata resulted in isolation of nine compounds, including a new ent-labdane diterpenoid, andrographic acid methyl ester (1), a new chalcone glucoside, pashanone glucoside (5), …
View article: Sulphated flavones and pregnane-type steroids from <i>Helicteres viscida</i>
Sulphated flavones and pregnane-type steroids from <i>Helicteres viscida</i> Open
In our search for anti-inflammatory constituents from Vietnamese plants, the methanolic extract of Helicteres viscida was found to exhibit inhibitory effect on LPS-induced NO production in RAW264.7 cells. Phytochemical investigation…
View article: Chemical constituents from the soft coral <i>Sinularia digitata</i>
Chemical constituents from the soft coral <i>Sinularia digitata</i> Open
Using various chromatographic separations, six known compounds namely (1 R *,2 E ,4 R *,7 E ,10 S *,11 S *,12 R *)‐10,18‐diacetoxy‐dolabella‐2,7‐dien‐6‐one ( 1 ), emblide ( 2 ), sarcophine ( 3 ), (3 R )‐4‐[(2 R ,4 S )‐4‐acetoxy‐2‐hydoxy‐2,…
View article: Anti‐inflammatory phenylpropanoid glycosides from the roots of <i>Polygala aureocauda</i> Dunn
Anti‐inflammatory phenylpropanoid glycosides from the roots of <i>Polygala aureocauda</i> Dunn Open
Chemical study on a methanol extract of the roots of Polygala aureocauda Dunn. resulted in the isolation of three phenylpropanoid glycosides, including β‐D‐[3‐ O ‐(3,4,5‐trimethoxycinnamoyl)]‐fructofuranosyl‐α‐D‐[6‐ O ‐(4‐methoxybenzoyl)]‐…
View article: Cytotoxic prenylated flavonoids from the leaves of Macaranga indica
Cytotoxic prenylated flavonoids from the leaves of Macaranga indica Open
View article: Prenylated flavonoids and other constituents from <i>Macaranga indica</i>
Prenylated flavonoids and other constituents from <i>Macaranga indica</i> Open
Four new prenylated flavonoids, macarindicins I-IV (1-4) together with ten known compounds, broussoflavonol F (5), vedelianin (6), schweinfurthin E (7), vitexin (8), 2″-rhamnosyl vitexin (9), isovi…
View article: Three new flavonol glycosides from <i>Fissistigma pallens</i>
Three new flavonol glycosides from <i>Fissistigma pallens</i> Open
Three new flavonol glycosides, fissflavosides A-C (1–3), together with six known flavonol glycosides, kaempferol 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-galactopyranoside (4), kaempferol 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside (5), k…
View article: The chemical constituents and biological activity of some sponges in Northern Vietnam: A review
The chemical constituents and biological activity of some sponges in Northern Vietnam: A review Open
Chemical composition and biological activity of sponges have been studied by the authors since 2006. So far, the authors have studied about 30 species of sponges, mainly collected cross in the sea of Northern Vietnam. Over 250 compounds ha…
View article: Three New Constituents From the Parasitic Plant <i>Balanophora laxiflora</i>
Three New Constituents From the Parasitic Plant <i>Balanophora laxiflora</i> Open
Three new constituents (1-3) were isolated from the whole plant of Balanophora laxiflora. Their chemical structures were elucidated by extensive analysis of high-resolution electrospray ionization mass spectrometry and nuclear magnetic res…
View article: Dendrodoristerol, a cytotoxic C20 steroid from the Vietnamese nudibranch mollusk <i>Dendrodoris fumata</i>
Dendrodoristerol, a cytotoxic C20 steroid from the Vietnamese nudibranch mollusk <i>Dendrodoris fumata</i> Open
Using various chromatographic separations, four steroids including one new C20 steroid namely dendrodoristerol (1), were isolated from the Vietnamese nudibranch mollusk Dendrodoris fumata. The structure elucidation…
View article: Triterpenoid derivatives from <i>Barringtonia racemosa</i>
Triterpenoid derivatives from <i>Barringtonia racemosa</i> Open
Using various chromatographic separations, two triterpenoid glucosides and three triterpenoid acids were isolated from a methanol extract of the Barringtonia racemosa branches and leaves. Their structures were elucidated as niga‐ichigoside…
View article: Acylated flavonoid glycosides from <i>Barringtonia racemosa</i>
Acylated flavonoid glycosides from <i>Barringtonia racemosa</i> Open
Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G–I (1–3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structu…