Chedi Erradhouani
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View article: A new alternative method using cyp3a65 expression in transgenic zebrafish embryos to assess metabolic endocrine-disrupting chemicals in the intestine
A new alternative method using cyp3a65 expression in transgenic zebrafish embryos to assess metabolic endocrine-disrupting chemicals in the intestine Open
Metabolic endocrine-disrupting chemicals (MDCs) contribute to the development and increasing incidence of metabolic disorders, highlighting the need for relevant assays to identify them. Several alternative models to mammals, notably the z…
View article: Metabolic disrupting chemicals in the intestine: the need for biologically relevant models
Metabolic disrupting chemicals in the intestine: the need for biologically relevant models Open
Although the concept of endocrine disruptors first appeared almost 30 years ago, the relatively recent involvement of these substances in the etiology of metabolic pathologies (obesity, diabetes, hepatic steatosis, etc.) has given rise to …
View article: Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors
Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors Open
The prevalence of metabolic diseases, such as obesity, diabetes, metabolic syndrome and chronic liver diseases among others, has been rising for several years. Epidemiology and mechanistic ( in vivo , in vitro and in silico ) toxicology ha…