Bin Tang
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View article: Case Report: A de novo NR2F1 mutation and clinical characteristics of Bosch–Boonstra–Schaaf optic atrophy syndrome in a Chinese patient
Case Report: A de novo NR2F1 mutation and clinical characteristics of Bosch–Boonstra–Schaaf optic atrophy syndrome in a Chinese patient Open
Purpose This study aimed to report the clinical characteristics, genetic findings, and treatment outcomes of a Chinese patient with Bosch–Boonstra–Schaaf optic atrophy syndrome (BBSOAS) caused by a mutation in the NR2F1 gene. Method A retr…
View article: Heterologous prime-boost immunization based on a human adenovirus 5 vectored containing Trichinella spiralis Cystatin-like protein elicits protective mucosal immunity in mice
Heterologous prime-boost immunization based on a human adenovirus 5 vectored containing Trichinella spiralis Cystatin-like protein elicits protective mucosal immunity in mice Open
Trichinellosis is a globally distributed zoonotic parasitic disease. The Trichinella infective larvae migrate through the intestine after ingestion and settle in muscles, thus intestinal mucosal immunity plays a vital role against early in…
View article: Genome-Wide Identification and Analysis of the AHL Gene Family in Pepper (Capsicum annuum L.)
Genome-Wide Identification and Analysis of the AHL Gene Family in Pepper (Capsicum annuum L.) Open
AT-hook motif nuclear-localized (AHL) genes play critical roles in chromatin remodeling and gene transcription regulation, profoundly influencing plant growth, development, and stress responses. While AHL genes have been extensively charac…
View article: A Comparative Study of Sugammadex and Neostigmine: A Bibliometric Analysis of the Past 15 Years
A Comparative Study of Sugammadex and Neostigmine: A Bibliometric Analysis of the Past 15 Years Open
Sugammadex surpasses neostigmine in rapidly, effectively, and safely reversing NMB induced by rocuronium/vecuronium across all depths. Its use expands to reversing residual NMB from NMBAs in various patient groups (hepatic/renal impairment…
View article: Identification of two new flavone 4′-O-methyltransferases and their application in de novo biosynthesis of (2S)-hesperetin in Yarrowia lipolytica
Identification of two new flavone 4′-O-methyltransferases and their application in de novo biosynthesis of (2S)-hesperetin in Yarrowia lipolytica Open
Methyltransferases are pivotal enzymes in the biosynthesis of methylated flavonoids, including (2S)-hesperetin. However, existing flavonoid 4'-O-methyltransferase (F4'OMT) enzymes typically exhibit low substrate specificity and catalytic e…
View article: Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients
Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients Open
Background Obstructive sleep apnea (OSA) is associated with poorer quality of life (QoL) and increased cardiovascular risks, which may be exacerbated by hypovitaminosis D. Sodium glucose transporter-2 inhibitor (SGLT2i) provides cardiovasc…
View article: Neuronal Network Activation Induced by Forniceal Deep Brain Stimulation in Mice
Neuronal Network Activation Induced by Forniceal Deep Brain Stimulation in Mice Open
Background: The fimbria-fornix is a nerve fiber bundle that connects various structures of the limbic system in the brain and plays a key role in cognition. It has become a major target of deep brain stimulation (DBS) to treat memory impai…
View article: Genome-Wide Identification and Analyses of the AHL Gene Family in Pepper (<em>Capsicum annuum</em> L.)
Genome-Wide Identification and Analyses of the AHL Gene Family in Pepper (<em>Capsicum annuum</em> L.) Open
The AT-hook motif nuclear-localized (AHL) genes play crucial roles in chromatin remodeling and regulation of gene transcription, significantly influencing biological processes such as plant growth, development, and stress responses. Althou…
View article: Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up
Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up Open
Objective This randomized controlled trial aims to evaluate the efficacy and safety of Yishenyangsui granule for treating Degenerative Cervical Myelopathy. Materials and methods A randomized, double-blind, placebo-controlled clinical trial…
View article: Identification of the Granule-Bound Starch Synthase (GBSS) Genes Involved in Amylose Biosynthesis in Tartary Buckwheat (Fagopyrum tataricum (L.) Gaertn.)
Identification of the Granule-Bound Starch Synthase (GBSS) Genes Involved in Amylose Biosynthesis in Tartary Buckwheat (Fagopyrum tataricum (L.) Gaertn.) Open
Tartary buckwheat is a nutrient-rich pseudo-cereal whose starch contents, including amylose and amylopectin contents, and their properties hold significant importance for enhancing yield and quality. The granule-bound starch synthase (GBSS…
View article: The differences in intestinal microbiota between common and orange‐muscle of <scp><i>Haliotis gigantea</i></scp> and dietary influences on abalone's intestinal microbiota
The differences in intestinal microbiota between common and orange‐muscle of <span><i>Haliotis gigantea</i></span> and dietary influences on abalone's intestinal microbiota Open
Compared with common abalone, the orange‐muscle abalone ( Haliotis gigantea ) has an enhanced ability to accumulate carotenoids. Feeding on asparagus ( Gracilaria lemaneiformis ) was critical for maintaining carotenoid contents in H. gigan…
View article: Identification of RppSLN from an Elite Landrace: A Major Locus Conferring Resistance to Southern Corn Rust in Maize (Zea mays L.)
Identification of RppSLN from an Elite Landrace: A Major Locus Conferring Resistance to Southern Corn Rust in Maize (Zea mays L.) Open
Southern corn rust (SCR) is one of the most destructive foliar diseases in maize (Zea mays L.), resulting in significant yield losses. Therefore, the continuous identification of disease-resistant germplasm and the deployment of resistant …
View article: Characteristic spatial and frequency distribution of mutations in SCN1A
Characteristic spatial and frequency distribution of mutations in SCN1A Open
Background SCN1A is the most well-recognized and commonly mutated gene related to epilepsy. This study analyzed the characteristic spatial and frequency distributions of SCN1A mutations, aiming to provide important insight into the mutagen…
View article: The Interaction of<i>UBR4, LRP1</i>, and<i>OPHN1</i>in Refractory Epilepsy:<i>Drosophila</i>Model to Investigate the Oligogenic Effect on Epilepsy
The Interaction of<i>UBR4, LRP1</i>, and<i>OPHN1</i>in Refractory Epilepsy:<i>Drosophila</i>Model to Investigate the Oligogenic Effect on Epilepsy Open
Refractory epilepsy is an intractable neurological disorder that is currently difficult to achieve effective pharmacological control in clinical practice and can result in poor quality of life as well as increased mortality. Genetic factor…
View article: <i>Akkermansia muciniphila</i> : A promising probiotic against inflammation and metabolic disorders
<i>Akkermansia muciniphila</i> : A promising probiotic against inflammation and metabolic disorders Open
Metabolic disease is a worldwide epidemic that has become a public health problem. Gut microbiota is considered to be one of the important factors that maintain human health by regulating host metabolism. As an abundant bacterium in the ho…
View article: <i>IFIH1</i>variants are associated with generalised epilepsy preceded by febrile seizures
<i>IFIH1</i>variants are associated with generalised epilepsy preceded by febrile seizures Open
Background IFIH1 variants have been reported to be associated with immune-related disorders with/without seizures. It is unknown whether IFIH1 variants are associated with common epilepsy without acquired causes and the mechanism underlyin…
View article: Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification
Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification Open
acacetin induces P53 activation and promotes apoptosis of hepatic stellate cells thereby ameliorating hepatic fibrosis.
View article: Corrigendum: ATP6V0C is associated with febrile seizures and epilepsy with febrile seizures plus
Corrigendum: ATP6V0C is associated with febrile seizures and epilepsy with febrile seizures plus Open
[This corrects the article DOI: 10.3389/fnmol.2022.889534.].