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View article: Analysis of perioperative period coagulation function affected by antiepileptic drugs in epilepsy surgery
Analysis of perioperative period coagulation function affected by antiepileptic drugs in epilepsy surgery Open
Background Drug-resistant epilepsy is a chronic condition that refers to epilepsy that does not improve with adequate medication treatment. For such cases, surgical intervention is a crucial strategy. However, in some patients, hemorrhage …
View article: Study of the microstructure of brain white matter in medial temporal lobe epilepsy based on diffusion tensor imaging
Study of the microstructure of brain white matter in medial temporal lobe epilepsy based on diffusion tensor imaging Open
Objectives To compare the white matter (WM) asymmetry in left and right medial temporal lobe epilepsy (mTLE) with and without hippocampal sclerosis (HS+, HS–) and assess the correlation of preoperative asymmetry and the dynamics of WM fibe…
View article: Gamma network topology and pathological changes in drug-resistant temporal lobe epilepsy with cognitive deficits
Gamma network topology and pathological changes in drug-resistant temporal lobe epilepsy with cognitive deficits Open
Temporal lobe epilepsy (TLE) is the most common form of adult epilepsy, frequently accompanied with cognitive deficits. The present study aims to investigate functional network alterations affected by cognitive impairments in drug-resistan…
View article: A Quantitative MRI Index for Assessing the Severity of Hippocampal Sclerosis in Temporal Lobe Epilepsy
A Quantitative MRI Index for Assessing the Severity of Hippocampal Sclerosis in Temporal Lobe Epilepsy Open
Background Hippocampal sclerosis (HS) is associated with post-surgery outcome in patients with temporal lobe epilepsy (TLE), and an automated method that quantifies HS severity is still lacking. Here, we aim to propose an MRI-based HS inde…
View article: MOESM1 of The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis
MOESM1 of The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis Open
Additional file 1: Table S1. Target sequences of ALKBH7. Table S2. Primer sequences of ALKBH7 and GAPDH used in qPCR. Table S3. Identified proteins in IP assay for bioinformatic analysis. Table S4. Enriched Gene ontology and pathway catego…
View article: Transcriptome profiling of the subventricular zone and dentate gyrus in an animal model of Parkinson's disease
Transcriptome profiling of the subventricular zone and dentate gyrus in an animal model of Parkinson's disease Open
Adult neurogenesis in the subventricular zone (SVZ), as well as in the subgranular zone contributes to brain maintenance and regeneration. In the adult brain, dopamine (DA) can regulate the endogenous neural stem cells within these two reg…
View article: Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma
Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma Open
In central nervous system, schwannomas, as ubiquitous tumors, mostly originate from sensory nerves like auditory and trigeminal nerves. However, intrasellar schwannomas are extremely rare. They are often misdiagnosed as pituitary adenomas.…
View article: CD34 Over-Expression is Associated With Gliomas’ Higher WHO Grade
CD34 Over-Expression is Associated With Gliomas’ Higher WHO Grade Open
CD34 is a transmembrane phosphoglycoprotein that was first identified on hematopoietic stem and progenitor cells. CD34 is known as an optimum marker for microvascular density studies and it is positively stained in pathological and physiol…