Jidong Chen
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View article: CellBin:a generalist framework to process spatial omics data to cell level
CellBin:a generalist framework to process spatial omics data to cell level Open
Spatial omics has rapidly expanded with increasingly diverse imaging modalities, molecular targets, and chip sizes. However, no general framework currently exists to construct cell level matrices that are robust across platforms and omics …
View article: How to Improve Collaboration in Sustainable Urban Community Renewal? An Evolutionary Game Model
How to Improve Collaboration in Sustainable Urban Community Renewal? An Evolutionary Game Model Open
Urban community renewal is an important direction for sustainable urban development in the era of building stock. Unlike traditional construction projects, the deeper involvement of residents in community renewal leads to more complex stak…
View article: Hydronephrosis-Associated Renal Fibrosis: Clinical Validation of Spp1 as a Biomarker and Therapeutic Target
Hydronephrosis-Associated Renal Fibrosis: Clinical Validation of Spp1 as a Biomarker and Therapeutic Target Open
Background: Renal fibrosis is a key driver of chronic kidney disease, often leading to end-stage renal disease (ESRD). Secreted phosphoprotein 1 (Spp1) is implicated in fibrotic processes, but its specific role in renal fibrosis, particula…
View article: Vasohibins in Health and Disease: From Angiogenesis to Tumorigenesis, Multiorgan Dysfunction, and Brain–Heart Remodeling
Vasohibins in Health and Disease: From Angiogenesis to Tumorigenesis, Multiorgan Dysfunction, and Brain–Heart Remodeling Open
Vasohibins (VASHs), comprising VASH-1 and VASH-2, were initially identified as regulators of angiogenesis. Recent studies, however, have unveiled their novel role in fibrosis and microtubule detyrosination. The dysregulated expression of V…
View article: Ordered Phase Transformation and Nanotwin Formation of Cu-15ni-8sn-0.2nb Alloy Induced by Cold Deformation Aging to Achieve Ultra-High Strength and Good Plasticity
Ordered Phase Transformation and Nanotwin Formation of Cu-15ni-8sn-0.2nb Alloy Induced by Cold Deformation Aging to Achieve Ultra-High Strength and Good Plasticity Open
View article: On Concepts, Analytics, and Statistics in Comparative Policy Studies: An Introduction from the New Section Editors
On Concepts, Analytics, and Statistics in Comparative Policy Studies: An Introduction from the New Section Editors Open
Effective comparative public policy research necessitates three key aspects. Firstly, it requires concepts that allow the differences in policies and policy developments across various domains to be discerned. Secondly, even with robust co…
View article: CogView3: Finer and Faster Text-to-Image Generation via Relay Diffusion
CogView3: Finer and Faster Text-to-Image Generation via Relay Diffusion Open
Recent advancements in text-to-image generative systems have been largely driven by diffusion models. However, single-stage text-to-image diffusion models still face challenges, in terms of computational efficiency and the refinement of im…
View article: The influence of microalloying and preparation process on phase transformation, mechanical properties, and friction/corrosion behavior of Cu–Ni–Sn alloys: A review
The influence of microalloying and preparation process on phase transformation, mechanical properties, and friction/corrosion behavior of Cu–Ni–Sn alloys: A review Open
This review provides an overview of Cu–Ni–Sn alloys, which have great advantages as a potential substitute for beryllium bronze. The characteristics of spinodal decomposition in Cu–Ni–Sn alloys are thoroughly discussed by conducting a comp…
View article: Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer
Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer Open
View article: Research Progress on Cu–15Ni–8Sn Alloys: The Effect of Microalloying and Heat Treatment on Microstructure and Properties
Research Progress on Cu–15Ni–8Sn Alloys: The Effect of Microalloying and Heat Treatment on Microstructure and Properties Open
Cu–15Ni–8Sn alloy is the best choice to replace beryllium bronze alloy. This alloy has unparalleled application value in aerospace, ocean engineering, electronic information, equipment manufacturing, and other fields. However, the applicat…
View article: Efficacy of Bushen Jiangu therapy in the treatment of glucocorticoid-induced osteoporosis: A systematic review and meta-analysis of randomized controlled trials
Efficacy of Bushen Jiangu therapy in the treatment of glucocorticoid-induced osteoporosis: A systematic review and meta-analysis of randomized controlled trials Open
Background: Glucocorticoid-induced osteoporosis (GIOP) is the most common secondary osteoporosis. Bushen Jiangu (BSJG), a classic traditional Chinese medicine (TCM) therapy, is widely used for treatment of GIOP. We conducted a meta-analysi…
View article: Efficacy and safety of Chinese herbal medicines combined with cyclophosphamide for connective tissue disease-associated interstitial lung disease: A meta-analysis of randomized controlled trials
Efficacy and safety of Chinese herbal medicines combined with cyclophosphamide for connective tissue disease-associated interstitial lung disease: A meta-analysis of randomized controlled trials Open
Objectives: To evaluate the effectiveness and safety of Chinese herbal medicines (CHMs) combined with cyclophosphamide (CTX) for connective tissue disease-associated interstitial lung disease (CTD-ILD) by performing a meta-analysis. Method…
View article: Efficacy and Safety of Chinese Herbal Medicines combined with Cyclophosphamide for Connective Tissue Disease-Associated Interstitial Lung Disease: A Meta-Analysis of Randomized Controlled Trials
Efficacy and Safety of Chinese Herbal Medicines combined with Cyclophosphamide for Connective Tissue Disease-Associated Interstitial Lung Disease: A Meta-Analysis of Randomized Controlled Trials Open
Review question / Objective: To evaluate the effectiveness and safety of Chinese herbal medicines (CHMs) combined with cyclophosphamide (CTX) for connective tissue disease-associated interstitial lung disease (CTD-ILD) by performing a meta…
View article: Effect of Mo on the Microstructures and Mechanical Properties of the Polycrystalline Superalloy with High W Content
Effect of Mo on the Microstructures and Mechanical Properties of the Polycrystalline Superalloy with High W Content Open
The effect of the Mo contents of 1.0 wt.%, 1.5 wt.%, 2.0 wt.%, and 3.0 wt.% on the microstructures and mechanical properties of the polycrystalline superalloy with a high W content was studied. The typical dendrite morphology was observed …
View article: Regulation of KDM5C stability and enhancer reprogramming in breast cancer
Regulation of KDM5C stability and enhancer reprogramming in breast cancer Open
View article: The persuasive role of the past: Policy feedback and citizens' acceptance of information communication technologies during the COVID‐19 pandemic in China
The persuasive role of the past: Policy feedback and citizens' acceptance of information communication technologies during the COVID‐19 pandemic in China Open
How can the enforcement of policies in the past influence a society's future adoption of information communication technologies (ICTs)? In this paper, we tackle this question by exploring how past e‐governance policies influence citizens' …
View article: Learning the Lexical Semantics of Mandarin Monomorphemic State-Change Verbs by English-Speaking Learners of Mandarin Chinese
Learning the Lexical Semantics of Mandarin Monomorphemic State-Change Verbs by English-Speaking Learners of Mandarin Chinese Open
Languages vary systematically in how semantic information is “packaged” in verbs and verb-related constructions. Mandarin Chinese contrasts typologically with English in its lexicalization of state change. Most Mandarin monomorphemic verbs…
View article: Inhibition of histone methyltransferase SETD8 represses DNA virus replication
Inhibition of histone methyltransferase SETD8 represses DNA virus replication Open
View article: Taken or Stuck by Natural Disaster? Evidence from Internal Labor Migration in China
Taken or Stuck by Natural Disaster? Evidence from Internal Labor Migration in China Open
View article: Government responsiveness and public acceptance of big-data technology in urban governance: Evidence from China during the COVID-19 pandemic
Government responsiveness and public acceptance of big-data technology in urban governance: Evidence from China during the COVID-19 pandemic Open
View article: miR-32-5p Inhibits the Proliferation, Migration and Invasion of Thyroid Cancer Cells by Regulating Twist1
miR-32-5p Inhibits the Proliferation, Migration and Invasion of Thyroid Cancer Cells by Regulating Twist1 Open
Background : Thyroid cancer is the most prevalent malignancy and one of the leading causes of cancer-related deaths. Recent studies have revealed that microRNAs (miRNAs) play an important role in tumorigenesis in various cancer types by af…
View article: Government Responsiveness and Public Acceptance of Big-Data Technology in Urban Governance: Evidence from China during the COVID-19 Pandemic
Government Responsiveness and Public Acceptance of Big-Data Technology in Urban Governance: Evidence from China during the COVID-19 Pandemic Open
View article: Classifier categories reflect but do not affect conceptual organization.
Classifier categories reflect but do not affect conceptual organization. Open
Do we structure object-related conceptual information according to real-world sensorimotor experience, or can it also be shaped by linguistic information? This study investigates whether a feature of language coded in grammar-numeral class…
View article: Optimized algorithm in solid thyroid nodule elastography
Optimized algorithm in solid thyroid nodule elastography Open
The present study aimed to evaluate the reproducibility and accuracy of the optimized algorithm of shear-wave elastography (SWE) in diagnosing solid thyroid nodules. Two hundred and sixty-three solid thyroid nodules in 248 patients who und…
View article: A time-sensitive network scheduling algorithm based on improved ant colony optimization
A time-sensitive network scheduling algorithm based on improved ant colony optimization Open
View article: A Longitudinal Study of the Acquisition of the Polysemous Verb 打 dǎ in Mandarin Chinese
A Longitudinal Study of the Acquisition of the Polysemous Verb 打 dǎ in Mandarin Chinese Open
Lexical ambiguity abounds in languages and multiple one-to-many form-function mappings create challenges for language learners. This study extends the theoretical approaches to the acquisition of polysemy to the Mandarin verb 打 dǎ, which i…
View article: The Acquisition of Mandarin Consonants by English Learners: The Relationship between Perception and Production
The Acquisition of Mandarin Consonants by English Learners: The Relationship between Perception and Production Open
This study investigates native English CFL (Chinese as a Foreign Language) learners’ difficulties with Mandarin consonants at the initial stage of learning and explores the relationship between second language (L2) speech perception and pr…
View article: Information Structure and Word Order Preference in Child and Adult Speech of Mandarin Chinese
Information Structure and Word Order Preference in Child and Adult Speech of Mandarin Chinese Open
The acquisition of appropriate linguistic markers of information structure (IS), e.g., word order and specific lexical and syntactic constructions, is a rather late development. This study revisits the debate on language-general preferred …
View article: Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs
Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs Open
Pulmonary arterial hypertension (PAH) is a disease with complex pathobiology, significant morbidity and mortality, and remains without a cure. It is characterized by vascular remodelling associated with uncontrolled proliferation of pulmon…
View article: Percutaneous sclerotherapy with polidocanol under the guidance of ultrasound for venous malformations in children – A retrospective cohort study from a single tertiary medical center
Percutaneous sclerotherapy with polidocanol under the guidance of ultrasound for venous malformations in children – A retrospective cohort study from a single tertiary medical center Open
This study reports our experience, the therapeutic outcomes and complications of percutaneous sclerotherapy (PS) with polidocanol to treat venous malformations (VMs) in children. A retrospective analysis was conducted of pediatric patients…