Yi Li
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View article: Translational Potential of an Electrospun Polycaprolactone Scaffold for Anterior Cruciate Ligament Reconstruction
Translational Potential of an Electrospun Polycaprolactone Scaffold for Anterior Cruciate Ligament Reconstruction Open
Anterior cruciate ligament (ACL) injuries are common and often require surgical reconstruction. Autografts remain the clinical standard for ACL reconstruction (ACLR) but are limited by donor site morbidity, inconsistent outcomes, and suppl…
View article: Adrenergic G protein-coupled receptors in liver physiology and pathology: research advances and clinical implications
Adrenergic G protein-coupled receptors in liver physiology and pathology: research advances and clinical implications Open
The liver, key for metabolism and homeostasis, sees growing focus on adrenergic GPCRs (α1/α2, β1/β2/β3; activated by adrenaline/noradrenaline). These receptors affect liver physiology/pathology and are treatment targets. This review explor…
View article: Semi-Supervised Transformer For Maxillofacial Ct Metal Artifact Reduction
Semi-Supervised Transformer For Maxillofacial Ct Metal Artifact Reduction Open
Aim or purpose: This study proposes Semi-SFTrans, a semi-supervised spatial-frequency transformer, for metal artifact reduction (MAR) in maxillofacial CT, evaluated against supervised models (Sup-SFTrans, ResUNet) and linear interpolation …
View article: Prohexadione calcium boosts pepper stem rigidity: coordinated regulation of hormonal crosstalk and lignin deposition drives xylem reinforcement
Prohexadione calcium boosts pepper stem rigidity: coordinated regulation of hormonal crosstalk and lignin deposition drives xylem reinforcement Open
View article: High-brightness photon-pair source based on high-Q multimode waveguide racetrack resonator
High-brightness photon-pair source based on high-Q multimode waveguide racetrack resonator Open
Efficient generation of correlated photon pairs through spontaneous four-wave mixing (SFWM) in silicon devices serves as a crucial resource for integrated quantum photonic technologies. Enhancing the intracavity field in high-quality-facto…
View article: MotionTrans: Human VR Data Enable Motion-Level Learning for Robotic Manipulation Policies
MotionTrans: Human VR Data Enable Motion-Level Learning for Robotic Manipulation Policies Open
Scaling real robot data is a key bottleneck in imitation learning, leading to the use of auxiliary data for policy training. While other aspects of robotic manipulation such as image or language understanding may be learned from internet-b…
View article: Analysis of Nutritional Components in Brown Sugar and Its Effects on Anti-fatigue, Alleviation of Qi Deficiency and Blood Stasis, and Antioxidant Effects
Analysis of Nutritional Components in Brown Sugar and Its Effects on Anti-fatigue, Alleviation of Qi Deficiency and Blood Stasis, and Antioxidant Effects Open
Brown sugar (BS), Red granulated sugar (RGS) and White sugar(WS) are three key sweeteners and food additives in China. Notably, BS possesses significant nutritional value and has been widely used in Chinese medicine for its supportive ther…
View article: Loss of TRIM44 promotes renal cell carcinoma progression by regulating K48-linked ubiquitination of vimentin
Loss of TRIM44 promotes renal cell carcinoma progression by regulating K48-linked ubiquitination of vimentin Open
Tripartite motif-containing 44 (TRIM44), a member of the TRIM protein family, has emerged as a regulator in multiple cancer types, yet its functional role and molecular mechanisms in clear cell renal cell carcinoma (ccRCC) remain poorly ch…
View article: Evaluation and application of an innovative portable field endoscope: addressing battlefield and biosafety concerns
Evaluation and application of an innovative portable field endoscope: addressing battlefield and biosafety concerns Open
View article: Pi Ji Pills reshape the pancreatic cancer immune microenvironment and enhance the efficacy of gemcitabine through dual mechanisms of PI3K/AKT pathway blockade and NETs inhibition
Pi Ji Pills reshape the pancreatic cancer immune microenvironment and enhance the efficacy of gemcitabine through dual mechanisms of PI3K/AKT pathway blockade and NETs inhibition Open
PJP combats pancreatic cancer and enhances gemcitabine efficacy by remodeling the immunosuppressive tumor microenvironment. This anticancer effect may be attributed to a dual-target mechanism involving suppression of the PI3K/AKT pathway a…
View article: DNA Methylation–Based Epigenetic Clocks and Cardiovascular Disease
DNA Methylation–Based Epigenetic Clocks and Cardiovascular Disease Open
View article: Research on the Artistic Transformation Path of Haptic Feedback Technology in Emotional Interaction Design
Research on the Artistic Transformation Path of Haptic Feedback Technology in Emotional Interaction Design Open
This study focuses on the interdisciplinary field of haptic feedback technology and emotional interaction design, systematically exploring the artistic transformation path of haptic feedback from technical implementation to emotional exper…
View article: A large language model system for the field of chemical engineering technology
A large language model system for the field of chemical engineering technology Open
The development of chemical engineering technology is a multi-stage process that encompasses laboratory research, scaling up, and industrial deployment. This process demands interdisciplinary col laboration and typically incurs significant…
View article: POU6F1 promote lumbar motor circuit reorganization following spinal cord injury
POU6F1 promote lumbar motor circuit reorganization following spinal cord injury Open
Spinal cord injury (SCI) causes irreversible motor deficits due to disrupted lumbar circuitry. However, transcriptional mechanisms in distal lumbar circuits are poorly understood. We identify POU6F1 as a critical transcriptional regulator …
View article: Simulation study on mechanical properties of NPR new material tank specimens under impact loading
Simulation study on mechanical properties of NPR new material tank specimens under impact loading Open
To elucidate the mechanical response of novel negative Poisson’s ratio (NPR) material tanks under impact loading and to assess their impact resistance, this study investigates tank specimens fabricated from NPR materials within the constra…
View article: Local vibration modal characteristics of functionalized negative Poisson’s ratio composites modified tanker car bodies
Local vibration modal characteristics of functionalized negative Poisson’s ratio composites modified tanker car bodies Open
To address the safety hazards of structural fatigue and sealing failure caused by vibration in the operation of tanker trucks, this thesis adopts excimer laser technology to prepare functionalized negative Poisson’s ratio composites for mo…
View article: An innovative statistical framework: A simulation study and practical implementations in the dance education, reliability engineering and radiation sector
An innovative statistical framework: A simulation study and practical implementations in the dance education, reliability engineering and radiation sector Open
View article: Identifying gut microbiota Faecalibacterium as a potential biomarker for distinguishing visceral or subcutaneous obese population
Identifying gut microbiota Faecalibacterium as a potential biomarker for distinguishing visceral or subcutaneous obese population Open
Background Obesity is a global health issue, with sharply increasing rates due to excessive food intake and reduced physical activity, leading to an increased risk of various chronic diseases, such as type 2 diabetes and cardiovascular dis…
View article: Clinical value of fluorescence laparoscopic surgery on anastomotic leakage prevention in ultra-low rectal cancer: real-world multicenter retrospective evidence with neoadjuvant chemoradiotherapy stratification
Clinical value of fluorescence laparoscopic surgery on anastomotic leakage prevention in ultra-low rectal cancer: real-world multicenter retrospective evidence with neoadjuvant chemoradiotherapy stratification Open
Fluorescence-guided laparoscopic surgery reduces anastomotic leakage and improves outcomes in low rectal cancer, especially after chemoradiotherapy, by enhancing surgical precision and recovery.
View article: Lanthanum nanoparticles-loaded polyurethane foam sponge for phosphorus recovery from water and subsequent hydroponic cultivation
Lanthanum nanoparticles-loaded polyurethane foam sponge for phosphorus recovery from water and subsequent hydroponic cultivation Open
View article: Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus
Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus Open
View article: Prohexadione calcium and KH2PO4 synergy optimizes pod pepper plant architecture for mechanized harvesting and boosts yield and fruit quality
Prohexadione calcium and KH2PO4 synergy optimizes pod pepper plant architecture for mechanized harvesting and boosts yield and fruit quality Open
View article: Global burden and cross-national inequalities of tobacco-attributable cancers in adults aged 40 and above, 1990–2021: a population-based study
Global burden and cross-national inequalities of tobacco-attributable cancers in adults aged 40 and above, 1990–2021: a population-based study Open
Background Tobacco exposure substantially increases the global cancer burden; however, studies targeting specific subgroups are scarce. We aimed to investigate global burden trends of tobacco-attributable cancers among people aged ≥40 and …
View article: Shaping Magnetic Liquid Metals Into 3D Leakage‐Free, Shape‐Programmable Structures and Electronics
Shaping Magnetic Liquid Metals Into 3D Leakage‐Free, Shape‐Programmable Structures and Electronics Open
Liquid metals (LMs), renowned for their high conductivity and large deformability, find increasing applications including in flexible electronics and soft robotics. One critical process in these applications is the precise patterning of LM…
View article: Successful treatment of advanced Birt-Hogg-Dubé syndrome-associated renal cell carcinoma with sarcomatoid dedifferentiation using anlotinib combined with PD-1 inhibitor after first-line therapy failure: a case report
Successful treatment of advanced Birt-Hogg-Dubé syndrome-associated renal cell carcinoma with sarcomatoid dedifferentiation using anlotinib combined with PD-1 inhibitor after first-line therapy failure: a case report Open
View article: Diagnostic accuracy evaluation of individual or combinational fecal immunochemical test, M3 gene, KRAS mutation and tumor methylation burden in colorectal carcinoma
Diagnostic accuracy evaluation of individual or combinational fecal immunochemical test, M3 gene, KRAS mutation and tumor methylation burden in colorectal carcinoma Open
Objective This study is aimed to develop multivariate prediction method in colorectal cancer (CRC) diagnosis. Methodology M3 gene expression was determined using Fecal DNA extraction kits and performed by qRT-PCR. Methylation-burden and KR…
View article: Blood metabolites, mitochondrial biofunction, and cervical cancer: a bidirectional Mendelian randomization study
Blood metabolites, mitochondrial biofunction, and cervical cancer: a bidirectional Mendelian randomization study Open
View article: Identification of <scp>BAHD</scp>‐acyltransferase enzymes involved in ingenane diterpenoid biosynthesis
Identification of <span>BAHD</span>‐acyltransferase enzymes involved in ingenane diterpenoid biosynthesis Open
Summary The plant family Euphorbiaceae is an abundant source of structurally complex diterpenoids, many of which have reported anticancer, anti‐HIV, and anti‐inflammatory activities. Among these, ingenol‐3‐angelate ( 1a ; tradename: Picato…
View article: Advances in the treatment of malignant tumors with neurological drugs
Advances in the treatment of malignant tumors with neurological drugs Open
The nervous system governs the body's components and is essential for the physiological functions of all organ systems. The nervous system governs how the body senses, processes, and responds to its environment. Through a complex network o…
View article: <scp>GATA1</scp> Transcriptionally Upregulates <scp>LMCD1</scp> , Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/ <scp>YAP</scp> Pathway
<span>GATA1</span> Transcriptionally Upregulates <span>LMCD1</span> , Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/ <span>YAP</span> Pathway Open
Sepsis‐associated acute kidney injury (SA‐AKI) is associated with morbidity and mortality. Ferroptosis is associated with the pathophysiology of SA‐AKI. Here, we investigated the role of LIM and cysteine‐rich domain 1 (LMCD1) in the regula…