Chen Yanovich
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View article: Effect of bone marrow blood versus peripheral blood on the hemostatic balance of osteoblasts and endothelial cells
Effect of bone marrow blood versus peripheral blood on the hemostatic balance of osteoblasts and endothelial cells Open
Bone and bone-marrow (BM) have the same blood supply and thus may be considered as one organ. We previously demonstrated that the microcirculation hemostatic balance that includes heparanase, tissue factor (TF), TF pathway inhibitor (TFPI)…
View article: Steroids and Malignancy Increase Local Heparanase and Decrease Markers of Osteoblast Activity in Bone Tissue Microcirculation
Steroids and Malignancy Increase Local Heparanase and Decrease Markers of Osteoblast Activity in Bone Tissue Microcirculation Open
Bone metastasis and steroids are known to activate the coagulation system and induce osteoporosis, pathological bone fractures, and bone pain. Heparanase is a protein known to enhance the hemostatic system and to promote angiogenesis, meta…
Augmented Degradation of Factors VIII and IX in the Intermittent Movement State Open
The most common clinical presentation of hemophilia A and hemophilia B is bleeding in large joints and striated muscles. It is unclear why bleeding has a predilection to affect joints and muscles. As muscles and joints are involved in inte…