Ching‐Yi Lin
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View article: Privacy paradox among romantic couples: the use of location sharing apps
Privacy paradox among romantic couples: the use of location sharing apps Open
The proliferation of smartphones has elevated privacy concerns, particularly regarding the easy access to geolocation information. Scholars have attempted to find a balance between location sharing and privacy protection; however, such a b…
View article: Multi-Hop Privacy Propagation for Differentially Private Federated Learning in Social Networks
Multi-Hop Privacy Propagation for Differentially Private Federated Learning in Social Networks Open
Federated learning (FL) enables collaborative model training across decentralized clients without sharing local data, thereby enhancing privacy and facilitating collaboration among clients connected via social networks. However, these soci…
View article: Sex Differences in Clinical Outcomes and Surgical Interventions for Infective Endocarditis: A Nationwide Registry
Sex Differences in Clinical Outcomes and Surgical Interventions for Infective Endocarditis: A Nationwide Registry Open
Background Sex differences in infective endocarditis (IE) remain underexplored in large-scale studies. Current findings on clinical outcomes, particularly in surgical IE, are inconsistent, highlighting critical knowledge gaps. Methods We c…
View article: Advances in Properties and Applications of Graphene Composites Advances in Properties and Applications of Graphene Composites
Advances in Properties and Applications of Graphene Composites Advances in Properties and Applications of Graphene Composites Open
Graphene is a two-dimensional material with unique structure and special properties. Due to the excellent mechanical properties, antibacterial barrier properties and electrical conductivity of the composite material, it has been used in ma…
View article: Exploring the Dissemination and Development of Culture: The Protection and Inheritance of Glove Puppetry
Exploring the Dissemination and Development of Culture: The Protection and Inheritance of Glove Puppetry Open
As a traditional folk art form originating from Fujian Province, China, and included in the Intangible Cultural Heritage List, glove puppetry has a profound historical background and rich and unique cultural connotations. With the promotio…
View article: Hemichordate cis-regulatory genomics and the gene expression dynamics of deuterostomes
Hemichordate cis-regulatory genomics and the gene expression dynamics of deuterostomes Open
Deuterostomes are one major group of bilaterians composed by hemichordates and echinoderms (collectively called Ambulacraria) and chordates. Comparative studies between these groups can provide valuable insights into the nature of the last…
View article: Chromosome-level genome assemblies of 2 hemichordates provide new insights into deuterostome origin and chromosome evolution
Chromosome-level genome assemblies of 2 hemichordates provide new insights into deuterostome origin and chromosome evolution Open
Deuterostomes are a monophyletic group of animals that includes Hemichordata, Echinodermata (together called Ambulacraria), and Chordata. The diversity of deuterostome body plans has made it challenging to reconstruct their ancestral condi…
View article: The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice
The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice Open
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motor neurons from the brain and spinal cord. The excessive neuroinflammation is thought to be a common determinant of ALS. Suppressor of cytokine signaling-3 …
View article: Tracing the Evolutionary Origin of Chordate Somites in the Hemichordate <i>Ptychodera flava</i>
Tracing the Evolutionary Origin of Chordate Somites in the Hemichordate <i>Ptychodera flava</i> Open
Synopsis Metameric somites are a novel character of chordates with unclear evolutionary origins. In the early branching chordate amphioxus, anterior somites are derived from the paraxial mesodermal cells that bud off the archenteron (i.e.,…
View article: Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution
Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution Open
Deuterostomes are an animal superphylum that includes Hemichordata and Echinodermata (together Ambulacraria) and Chordata. The diversity of deuterostome body plans has made it challenging to reconstruct their ancestral condition and to dec…
View article: Embryonic and post-embryonic development in the parasitic copepod Ive ptychoderae (Copepoda: Iviidae): Insights into its phylogenetic position
Embryonic and post-embryonic development in the parasitic copepod Ive ptychoderae (Copepoda: Iviidae): Insights into its phylogenetic position Open
Parasitic copepods are frequently discovered in many marine animals, and they exhibit great species diversity with remarkable morphological adaptations to their parasitic lifestyle. Similar to their free-living relatives, parasitic copepod…
View article: Upregulated 5-HT <sub>1A</sub> Receptors Regulate Lower Urinary Tract Function in Rats after Complete Spinal Cord Injury
Upregulated 5-HT <sub>1A</sub> Receptors Regulate Lower Urinary Tract Function in Rats after Complete Spinal Cord Injury Open
Spinal cord injury (SCI) above the lumbosacral level often leads to dysfunction of the lower urinary tract (LUT) including detrusor hyper-reflexia, wherein bladder compliance is low, baseline pressures are increased, and filling is accompa…
View article: Interactions between Obstructive Sleep Apnea Syndrome Severity, Obesity, Sex Difference and Attention-Deficit/Hyperactivity Disorder on Health-Related Quality of Life: A Non-Interventional Prospective Observational Study
Interactions between Obstructive Sleep Apnea Syndrome Severity, Obesity, Sex Difference and Attention-Deficit/Hyperactivity Disorder on Health-Related Quality of Life: A Non-Interventional Prospective Observational Study Open
Obstructive sleep apnea syndrome (OSAS) severity, obesity, sex difference, and attention-deficit/hyperactivity disorder (ADHD) had a complex impact on health-related quality of life (HRQoL). However, the interactive effects among these fea…
View article: Insights into deuterostome evolution from the biphasic transcriptional programme of hemichordates
Insights into deuterostome evolution from the biphasic transcriptional programme of hemichordates Open
Evolutionary history of deuterostomes remains unsolved and is intimately related to the origin of chordates. Among deuterostomes, hemichordates and echinoderms (collectively called Ambulacraria) are sister groups of chordates. Comparative …
View article: Targeting of Mcl-1 Expression by MiRNA-3614-5p Promotes Cell Apoptosis of Human Prostate Cancer Cells
Targeting of Mcl-1 Expression by MiRNA-3614-5p Promotes Cell Apoptosis of Human Prostate Cancer Cells Open
MicroRNA (miRNA) acts as a critical regulator of growth in various human malignancies. However, the role of miRNA-3614 in the progression of human prostate cancer remains unknown. In this study, our results demonstrated that miRNA-3614-5p …
View article: Mitochondrial haplogroups have a better correlation to insulin requirement than nuclear genetic variants for type 2 diabetes mellitus in Taiwanese individuals
Mitochondrial haplogroups have a better correlation to insulin requirement than nuclear genetic variants for type 2 diabetes mellitus in Taiwanese individuals Open
Aims/Introduction Identifying diabetes‐susceptible genetic variants will help to provide personalized therapy for the management of type 2 diabetes. Previous studies have reported a genetic risk score (GRS), computed by the sum of nuclear …
View article: The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in Diabetes
The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in Diabetes Open
Background: Plenty of evidence suggested that chronic low-grade inflammation triggered by innate immunity activation contributes to the pathogenesis of type 2 diabetes (T2D). Using the trans-mitochondrial cybrid cell model, we have demonst…
View article: Changes in the number and causes of maternal deaths after the introduction of pregnancy checkbox on the death certificate in Taiwan
Changes in the number and causes of maternal deaths after the introduction of pregnancy checkbox on the death certificate in Taiwan Open
The number of maternal deaths increased, and the distribution of causes of maternal deaths changed after the introduction of pregnancy checkbox. Additional studies are required to examine the possible misclassification of pregnancy-associa…
View article: Employing GIS towards shaping a smart and sustainable future: a brief policy survey of global and Taiwan’s efforts
Employing GIS towards shaping a smart and sustainable future: a brief policy survey of global and Taiwan’s efforts Open
Since UN announced 17 SDGs in 2015, many countries around the world have been endeavouring to promote SDGs towards building a sustainable future. Given the disparity of the regional development, national government is suggested to establis…
View article: BMP controls dorsoventral and neural patterning in indirect-developing hemichordates providing insight into a possible origin of chordates
BMP controls dorsoventral and neural patterning in indirect-developing hemichordates providing insight into a possible origin of chordates Open
A defining feature of chordates is the unique presence of a dorsal hollow neural tube that forms by internalization of the ectodermal neural plate specified via inhibition of BMP signaling during gastrulation. While BMP controls dorsoventr…
View article: 5S Dashboard Design Principles for Self-Service Business Intelligence Tool User
5S Dashboard Design Principles for Self-Service Business Intelligence Tool User Open
Non–information technology (IT) professionals and nonexpert casual users are increasingly adopting self-service business intelligence (SSBI) tools (such as Tableau, Qlik, and Power BI) to create data visualization dashboards. This study id…
View article: Correction: Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease
Correction: Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease Open
Sun, K., X. Li, X. Chen, Y. Bai, G. Zhou, O. N. Kokiko-Cochran, B. Lamb, T. A. Hamilton, C.-Y. Lin, Y.-S. Lee, and T. Herjan. 2018. Neuron-specific HuR-deficient mice spontaneously develop motor neuron disease. J . Immunol . 201: [157–166]…
View article: Differential Adaptations of the Musculoskeletal System after Spinal Cord Contusion and Transection in Rats
Differential Adaptations of the Musculoskeletal System after Spinal Cord Contusion and Transection in Rats Open
Spinal cord injury (SCI) causes impaired neuronal function with associated deficits in the musculoskeletal system, which can lead to permanent disability. Here, the impact of SCI on in vivo musculoskeletal adaptation was determined by stud…
View article: Nimbolide induces mitochondrial-dependent apoptosis through activation of ERK1/2 mediated inhibition of clapsin expression in human hepatocellular carcinoma cells
Nimbolide induces mitochondrial-dependent apoptosis through activation of ERK1/2 mediated inhibition of clapsin expression in human hepatocellular carcinoma cells Open
Nimbolide is a tetranortriterpenoid isolated from the leaves and flowers of Azadirachta indica which has been shown to exhibit anti-tumor, anti-inflammatory, and anti-invasive properties in a variety of cancer cells. However, the antitumor…
View article: The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species
The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species Open
Background . Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that…
View article: Praeruptorin A Inhibits Human Cervical Cancer Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling
Praeruptorin A Inhibits Human Cervical Cancer Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling Open
Praeruptorin A (PA) is a pyranocumarin present in the dried root of Peucedanumpraeruptorum Dunn that has anticancer effects against several types of cells. However, the effect of PA on human cervical cancer cells is unknown. Our results in…
View article: Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin
Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin Open
Previous studies reported that norcantharidin (NCTD) has anti-tumor effects. We investigated the antitumor effects and underlying mechanism of NCTD on human renal cancer in vitro and in vivo. NCTD significantly decreased renal cancer cell …