Chendan Jiang
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View article: The Spectra of Pathogenic Variants and Phenotypes in a Chinese Cohort of 298 Families with Osteogenesis Imperfecta
The Spectra of Pathogenic Variants and Phenotypes in a Chinese Cohort of 298 Families with Osteogenesis Imperfecta Open
Background: Osteogenesis imperfecta (OI) is marked by clinical and genetic heterogeneity, and the genotype–phenotype correlation remains not very clear. We conducted a clinical and genetic study in a Chinese OI cohort to determine the spec…
View article: Clinical, genomic, and histopathologic diversity in cerebral cavernous malformations
Clinical, genomic, and histopathologic diversity in cerebral cavernous malformations Open
Cerebral cavernous malformations (CCMs) are hemorrhagic vascular disorders with varied clinical and radiological presentations, occurring sporadically due to MAP3K3 or PIK3CA mutations or through inherited germline mutations of CCM genes. …
View article: GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas
GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas Open
View article: Correlation Of Genotype and Clinical Phenotype in Cerebral Cavernous Malformations: A Multicenter Cohort Study
Correlation Of Genotype and Clinical Phenotype in Cerebral Cavernous Malformations: A Multicenter Cohort Study Open
View article: Machine Learning Approaches to Differentiate Sellar-Suprasellar Cystic Lesions on Magnetic Resonance Imaging
Machine Learning Approaches to Differentiate Sellar-Suprasellar Cystic Lesions on Magnetic Resonance Imaging Open
Cystic lesions are common lesions of the sellar region with various pathological types, including pituitary apoplexy, Rathke’s cleft cyst, cystic craniopharyngioma, etc. Suggested surgical approaches are not unique when dealing with differ…
View article: Feasibility of evaluating the histologic and genetic subtypes of WHO grade II-IV gliomas by diffusion-weighted imaging
Feasibility of evaluating the histologic and genetic subtypes of WHO grade II-IV gliomas by diffusion-weighted imaging Open
View article: Feasibility of Evaluating the Histologic and Genetic Subtypes of WHO Grade II-IV Gliomas by Diffusion-Weighted Imaging
Feasibility of Evaluating the Histologic and Genetic Subtypes of WHO Grade II-IV Gliomas by Diffusion-Weighted Imaging Open
Background: To explore the feasibility of diffusion-weighted imaging (DWI) metrics to predict the histologic subtypes and genetic status of gliomas (e.g., IDH, MGMT, and TERT) noninvasively.Methods: One hundred and eleven patients with pat…
View article: Thin-Slice Magnetic Resonance Imaging-Based Radiomics Signature Predicts Chromosomal 1p/19q Co-deletion Status in Grade II and III Gliomas
Thin-Slice Magnetic Resonance Imaging-Based Radiomics Signature Predicts Chromosomal 1p/19q Co-deletion Status in Grade II and III Gliomas Open
Objective: Chromosomal 1p/19q co-deletion is recognized as a diagnostic, prognostic, and predictive biomarker in lower grade glioma (LGG). This study aims to construct a radiomics signature to non-invasively predict the 1p/19q co-de…
View article: Feasibility of Evaluating the Histologic and Genetic Subtypes of WHO Grade II-IV Gliomas by Diffusion-Weighted Imaging
Feasibility of Evaluating the Histologic and Genetic Subtypes of WHO Grade II-IV Gliomas by Diffusion-Weighted Imaging Open
Background: To explore the feasibility of diffusion-weighted imaging (DWI) metrics in order to predict the histologic subtypes and genetic status (e.g., IDH, MGMT, and TERT) of glioma noninvasively.Methods: One hundred and eleven patients …
View article: 18F-FDG-PET-based Radiomics signature predicts MGMT promoter methylation status in primary diffuse glioma
18F-FDG-PET-based Radiomics signature predicts MGMT promoter methylation status in primary diffuse glioma Open
18F-FDG-PET-based radiomics is a promising approach for preoperatively evaluating the MGMT promoter methylation status in glioma and predicting the prognosis of glioma patients noninvasively.
View article: 18F-FDG-PET-based radiomics features to distinguish primary central nervous system lymphoma from glioblastoma
18F-FDG-PET-based radiomics features to distinguish primary central nervous system lymphoma from glioblastoma Open
The differential diagnosis of primary central nervous system lymphoma from glioblastoma multiforme (GBM) is essential due to the difference in treatment strategies. This study retrospectively reviewed 77 patients (24 with lymphoma and 53 w…