Jianxing He
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View article: The Effectiveness of Robotic-assisted Navigation System for Preoperative Lung Nodule Localization: a Prospective, Single-center, Non-inferiority, Randomized Clinical Study
The Effectiveness of Robotic-assisted Navigation System for Preoperative Lung Nodule Localization: a Prospective, Single-center, Non-inferiority, Randomized Clinical Study Open
Background: In recent years, robots specifically designed to assist localization have been developed. Nevertheless, limited studies have systematically investigated the integration of these systems into routine clinical practice. Methods: …
View article: Development of broadly neutralizing antibodies against Omicron variants from existing neutralizing antibodies in clinical trials
Development of broadly neutralizing antibodies against Omicron variants from existing neutralizing antibodies in clinical trials Open
View article: From nonintubation to tubeless: redefining perioperative strategies in modern anesthesiology and thoracic surgery
From nonintubation to tubeless: redefining perioperative strategies in modern anesthesiology and thoracic surgery Open
View article: Survival Prediction in Middle‐Aged and Elderly Patients With Burkitt Lymphoma: A Comprehensive Nomogram Approach Based on SEER Data
Survival Prediction in Middle‐Aged and Elderly Patients With Burkitt Lymphoma: A Comprehensive Nomogram Approach Based on SEER Data Open
Background Burkitt lymphoma (BL) in middle‐aged and elderly populations presents unique prognostic challenges due to distinct biological behaviors and therapeutic vulnerabilities. Current prognostic tools inadequately address age‐specific …
View article: Causal inference of modifiable lifestyle and birth traits on osteonecrosis risk: A bidirectional 2-sample Mendelian randomization study
Causal inference of modifiable lifestyle and birth traits on osteonecrosis risk: A bidirectional 2-sample Mendelian randomization study Open
Osteonecrosis (ON) is a progressive skeletal disorder caused by impaired bone perfusion and cell viability. While corticosteroid use and alcohol intake are established risk factors, the causal effects of modifiable lifestyle behaviors and …
View article: Effect of the tubeless approach on the non-operative lung in thoracic surgery: a retrospective cohort study
Effect of the tubeless approach on the non-operative lung in thoracic surgery: a retrospective cohort study Open
Tubeless approach is associated with lower mechanical ventilation pressures and less overall image abnormalities, potentially protecting the non-operative lung. These findings suggest that tubeless approach has protective effect on the non…
View article: Sintilimab plus chemotherapy for first-line treatment of advanced pulmonary lymphoepithelioma-like carcinoma: Phase 2 trial
Sintilimab plus chemotherapy for first-line treatment of advanced pulmonary lymphoepithelioma-like carcinoma: Phase 2 trial Open
Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a unique non-small cell lung cancer associated with Epstein-Barr virus (EBV), lacking a standard treatment. This phase 2 study evaluates sintilimab plus gemcitabine and carboplatin (4 c…
View article: Precise localization techniques for small pulmonary nodules: what is next?
Precise localization techniques for small pulmonary nodules: what is next? Open
With the widespread adoption of low-dose computed tomography (LDCT) screening, the detection rate of small pulmonary nodules has surged, necessitating precise localization for minimally invasive resection. Video-assisted thoracoscopic surg…
View article: Management of childhood granulomatous periorificial dermatitis with clarithromycin: A retrospective cohort study
Management of childhood granulomatous periorificial dermatitis with clarithromycin: A retrospective cohort study Open
View article: Treatments of depressive symptoms in cancer patients: A systematic review and network meta-analysis
Treatments of depressive symptoms in cancer patients: A systematic review and network meta-analysis Open
View article: Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant
Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant Open
Lung transplantation (LTx) is a life‐saving procedure for patients with end‐stage respiratory failure; however, primary graft dysfunction (PGD), primarily induced by ischemia/reperfusion injury (IRI), remains a major complication. Although…
View article: Distinct effects of three knee-preserving surgeries on hip-knee-ankle alignment in patients with knee osteoarthritis
Distinct effects of three knee-preserving surgeries on hip-knee-ankle alignment in patients with knee osteoarthritis Open
View article: A comprehensive investigation of the relationship between dietary fatty acid intake and preserved ratio impaired spirometry: multimethodology based on NHANES
A comprehensive investigation of the relationship between dietary fatty acid intake and preserved ratio impaired spirometry: multimethodology based on NHANES Open
View article: Dual Challenges and Innovative Strategies in Chimeric Antigen Receptor T-cell Therapy for Glioblastoma
Dual Challenges and Innovative Strategies in Chimeric Antigen Receptor T-cell Therapy for Glioblastoma Open
View article: Prediction and immune infiltration analysis of lipid metabolism-related immune genes in the treatment of non-small cell lung cancer
Prediction and immune infiltration analysis of lipid metabolism-related immune genes in the treatment of non-small cell lung cancer Open
This study investigates the role of lipid metabolism-related immune genes in the treatment of non-small cell lung cancer (NSCLC), with a particular focus on the differences between Lung adenocarcinoma (LUAD) and Lung squamous cell carcinom…
View article: Composite dietary antioxidant index and lung cancer risk: insights from the UK biobank
Composite dietary antioxidant index and lung cancer risk: insights from the UK biobank Open
This study revealed a significant link between increased dietary antioxidant intake and a reduced risk of lung cancer, particularly in former smokers.
View article: Improving Renal Transplant Outcomes through the Tubeless Anesthesia Technique in Renal Transplantation：A retrospective study
Improving Renal Transplant Outcomes through the Tubeless Anesthesia Technique in Renal Transplantation：A retrospective study Open
Objective To evaluate the feasibility and benefits of tubeless anesthesia (TA), using a laryngeal mask airway instead of endotracheal intubation (ETT), in renal transplantation, aligning with tubeless surgery principles. Methods A single-c…
View article: Potential effects of endocrine-disrupting chemicals on preserved ratio impaired spirometry revealed by five different approaches
Potential effects of endocrine-disrupting chemicals on preserved ratio impaired spirometry revealed by five different approaches Open
These findings suggest that exposure to EDCs may be linked to the prevalence of PRISm. These results provide novel epidemiological evidence for PRISm.
View article: Exploring the potential associations between single and mixed volatile compounds and preserved ratio impaired spirometry using five different approaches
Exploring the potential associations between single and mixed volatile compounds and preserved ratio impaired spirometry using five different approaches Open
Our findings demonstrate the correlations between VOCs and PRISm, with inflammation potentially mediating the relationship. The machine learning results highlight the potential of combining VOCs with demographic characteristics to improve …
View article: Integrating a Multimodal Digital Device for Continuous Perioperative Monitoring in Patients With Lung Cancer Undergoing Thoracic Surgery: Development and Usability Study
Integrating a Multimodal Digital Device for Continuous Perioperative Monitoring in Patients With Lung Cancer Undergoing Thoracic Surgery: Development and Usability Study Open
Background Minimally invasive thoracic surgery has improved lung cancer outcomes but requires enhanced postoperative care. Traditionally, the episodic care model has limited timely and multidimensional monitoring of patients. Recent techno…
View article: Bibliometric insights into the cell cycle, aging, and metabolism: from molecular mechanisms to clinical implications
Bibliometric insights into the cell cycle, aging, and metabolism: from molecular mechanisms to clinical implications Open
Cell cycle regulation, aging, and metabolism are pivotal biological processes linked to both normal physiology and disease development. Understanding their interplay is crucial for advancing gerontological research and clinical oncology. W…
View article: McKeown minimally invasive esophagectomy under discontinuous spontaneous ventilating anesthesia by laryngeal mask: a retrospective non-inferiority cohort study
McKeown minimally invasive esophagectomy under discontinuous spontaneous ventilating anesthesia by laryngeal mask: a retrospective non-inferiority cohort study Open
The technique of discontinuous spontaneous ventilating anesthesia by laryngeal mask for MIE-McKeown is considered feasible. Careful evaluation of the patients, preoperative assessment and skillful surgical technique are the key factors of …
View article: Mutations in the PGAM1 gene, encoding phosphoglycerate mutase-like protein 1, result in cold tolerance in the tomato plant mutant ‘cr-1′
Mutations in the PGAM1 gene, encoding phosphoglycerate mutase-like protein 1, result in cold tolerance in the tomato plant mutant ‘cr-1′ Open
View article: Global mortality burden of lung cancer and mesothelioma attributable to occupational asbestos exposure and the impact of national asbestos ban policies: a population-based study, 1990–2021
Global mortality burden of lung cancer and mesothelioma attributable to occupational asbestos exposure and the impact of national asbestos ban policies: a population-based study, 1990–2021 Open
Introduction Asbestos-related thoracic cancers (ARTCs), including asbestos-related lung cancer and mesothelioma, constitute the majority of deaths due to asbestos exposure. This study evaluates the global mortality burden of ARTCs and the …
View article: Optimizing core needle biopsy specimen collection techniques to enhance molecular testing adequacy in non-small cell lung cancer
Optimizing core needle biopsy specimen collection techniques to enhance molecular testing adequacy in non-small cell lung cancer Open
The use of PPMMs significantly enhances CNB specimen quality and molecular testing adequacy in NSCLC. Routine collection of cell pellets from the residual fixative medium is recommended to maximize diagnostic effectiveness and improve clin…
View article: S2S: A deep learning method for the radiological diagnosis of fine-grained diseases spanning screening to subtyping
S2S: A deep learning method for the radiological diagnosis of fine-grained diseases spanning screening to subtyping Open
View article: The combination of Astragali Radix and Anemarrhenae Rhizoma in the treatment of ultraviolet skin damage by regulating the PI3K-AKT pathway
The combination of Astragali Radix and Anemarrhenae Rhizoma in the treatment of ultraviolet skin damage by regulating the PI3K-AKT pathway Open
View article: Night shift work and lung cancer risk: a prospective cohort study with mediator analysis from the UK Biobank
Night shift work and lung cancer risk: a prospective cohort study with mediator analysis from the UK Biobank Open
Study Objectives This study investigated the association between night shift work and lung cancer risk using data from the UK Biobank cohort of 278 650 participants, while exploring potential biological mediators and gene–environment inter…
View article: Neoadjuvant Osimertinib for Resectable <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer
Neoadjuvant Osimertinib for Resectable <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer Open
PURPOSE Adjuvant osimertinib is the standard of care for patients with resected epidermal growth factor receptor ( EGFR )–mutated non–small cell lung cancer (NSCLC). Neoadjuvant treatment could improve surgical and long-term outcomes. METH…
View article: Physiological pattern differences in non-intubated vs. intubated thoracic anesthesia based on time series analysis
Physiological pattern differences in non-intubated vs. intubated thoracic anesthesia based on time series analysis Open
Using a real-time database, the non-intubated thoracic anesthesia management pattern is firstly clearly demonstrated, which differs from the intubated anesthesia with the machine-controlled pattern. Reducing intravenous anesthetics with re…