Ming‐Jen Cheng
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View article: Lepidium meyenii Walpers Promotes the Regeneration of Salivary Gland and Prevents Xerostomia After Irradiation Injury
Lepidium meyenii Walpers Promotes the Regeneration of Salivary Gland and Prevents Xerostomia After Irradiation Injury Open
Objectives: Lepidium meyenii Walpers (LMW), a high-altitude plant, is known to stimulate hormone release, counteract neurodegeneration, and protect against oxidative stress. Saliva is vital for oral health, and reduced production leads to …
View article: Porphyromonas gingivalis GroEL Accelerates Abdominal Aortic Aneurysm Formation by Induction of M1 Polarization in Macrophages
Porphyromonas gingivalis GroEL Accelerates Abdominal Aortic Aneurysm Formation by Induction of M1 Polarization in Macrophages Open
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease characterized by chronic inflammation, extracellular matrix degradation, and smooth muscle cell apoptosis. Porphyromonas gingivalis (P. gingivalis), a key periodontal p…
View article: Effects of different rootstocks on the growth physiology and enzyme activity of Artemisia selengensis
Effects of different rootstocks on the growth physiology and enzyme activity of Artemisia selengensis Open
In this experiment, wild-type Artemisia selengensis, Chrysanthemum, Artemisia annua and mugwort were used as rootstocks, while cultivated A. selengensis served as the scion. Cleft grafting was identified as the most effective method. The h…
View article: Species of Fusarium and Neocosmospora associated with citrus branch diseases in China
Species of Fusarium and Neocosmospora associated with citrus branch diseases in China Open
Species of Fusarium and related fusarioid genera are widely distributed and commonly associated with diverse plant hosts, either as saprobes, endophytes, or pathogens. Although fusarioid fungi have been implicated in citrus diseases worldw…
View article: The crude extract obtained from <i>Cinnamomum macrostemon</i> Hayata regulates oxidative stress and mitophagy in keratinocytes
The crude extract obtained from <i>Cinnamomum macrostemon</i> Hayata regulates oxidative stress and mitophagy in keratinocytes Open
Four ethanol fractionated crude extracts (EFCEs [A-D]) purified from the leaves of Cinnamomum macrostemon Hayata were screened for antioxidative effects and mitochondrial function in HaCaT cells. The higher cell viability indicated that EF…
View article: Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424
Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424 Open
The mold Monascus, also called red yeast rice, anka, or koji, has been used as the natural food coloring agent and food additives for more than 1000 years in Asian countries. It has also been used in Chinese herbology and traditional Chine…
View article: Secondary metabolites from the leaves of Meliosma rhoifolia and evaluation of their cytotoxic activity
Secondary metabolites from the leaves of Meliosma rhoifolia and evaluation of their cytotoxic activity Open
One previously undescribed labdane diterpenoid, meliosmarhoifol (1), together with four known ones, 12R,15-dihydroxylabda-8(17),13E-dien-19-oic acid (2), 18-norlabda-8(17),14-diene-4α,13β-diol (3), 5α,6α-epoxy-(22E,24R)-ergosta-8(14),22-di…
View article: Antifungal Activities of Compounds Produced by Newly Isolated Acrocarpospora Strains
Antifungal Activities of Compounds Produced by Newly Isolated Acrocarpospora Strains Open
In our continued search for bioactive metabolites from cultures of rare Actinobacteria resources from all over Taiwan and various natural ecological environments, an active antimicrobial strain of Acrocarpospora punica 04107M was collected…
View article: Undescribed Metabolites from an Actinobacteria Acrocarpospora punica and Their Anti-Inflammatory Activity
Undescribed Metabolites from an Actinobacteria Acrocarpospora punica and Their Anti-Inflammatory Activity Open
In an effort to explore bioactive anti-inflammatory compounds from natural Actinobacteria resources from all over Taiwan and various ecological environments, an active strain of Acrocarpospora punica was collected at Taitung County in Taiw…
View article: Correction: Chen et al. Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis. Molecules 2022, 27, 1657
Correction: Chen et al. Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis. Molecules 2022, 27, 1657 Open
The authors wish to make the following changes to their paper [...]
View article: Correction: Cheng et al. Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides. Molecules 2022, 27, 437
Correction: Cheng et al. Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides. Molecules 2022, 27, 437 Open
The authors wish to make the following changes to their paper [...]
View article: Correction: Wu et al. Secondary Metabolites with Antimicrobial Activities from Chamaecyparis obtusa var. formosana. Molecules 2022, 27, 429
Correction: Wu et al. Secondary Metabolites with Antimicrobial Activities from Chamaecyparis obtusa var. formosana. Molecules 2022, 27, 429 Open
The authors wish to make the following changes to their paper [...]
View article: Secondary Metabolites with Anti-Inflammatory Activities from an Actinobacteria Herbidospora daliensis
Secondary Metabolites with Anti-Inflammatory Activities from an Actinobacteria Herbidospora daliensis Open
Bioassay-guided fractionation of extracts derived from solid cultures of a Herbidospora daliensis originating from Taiwan led to the isolation of five new compounds, for which we propose the name herbidosporadalins A–E (1–5), one isolated …
View article: Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis
Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis Open
The genus Cimicifuga is one of the smallest genera in the family Ranunculaceae. Cimicifugae Rhizoma originated from rhizomes of Cimicifuga simplex, and C. dahurica, C. racemosa, C. foetida, and C. heracleifolia have been used as anti-infla…
View article: Comparison of Various Solvent Extracts and Major Bioactive Components from Unsalt-Fried and Salt-Fried Rhizomes of Anemarrhena asphodeloides for Antioxidant, Anti-α-Glucosidase, and Anti-Acetylcholinesterase Activities
Comparison of Various Solvent Extracts and Major Bioactive Components from Unsalt-Fried and Salt-Fried Rhizomes of Anemarrhena asphodeloides for Antioxidant, Anti-α-Glucosidase, and Anti-Acetylcholinesterase Activities Open
The rhizome of Anemarrhena asphodeloides Bunge (AA, family Liliaceae) is a famous and frequently used herbal drug in the traditional medicine of Northeast Asia, under vernacular name “zhimu”. A. asphodeloides has been used as an anti-infla…
View article: Antioxidant and Anti-α-Glucosidase Activities of Various Solvent Extracts and Major Bioactive Components from the Fruits of Crataegus pinnatifida
Antioxidant and Anti-α-Glucosidase Activities of Various Solvent Extracts and Major Bioactive Components from the Fruits of Crataegus pinnatifida Open
Crataegus pinnatifida is used to treat various diseases, including indigestion, congestive heart failure, hypertension, atherosclerosis, and myocardial dysfunction. We evaluated antioxidant and anti-α-glucosidase activities of various solv…
View article: Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides
Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides Open
Five new dimer compounds, namely Taiwaniacryptodimers A–E (1–5), were isolated from the methanol extract of the roots of Taiwania cryptomerioides. Their structures were established by mean of spectroscopic analysis and comparison of NMR da…
View article: Anti-lymphangiogenic diterpenes from the bark of Calocedrus macrolepis var. formosana
Anti-lymphangiogenic diterpenes from the bark of Calocedrus macrolepis var. formosana Open
Eight new diterpenes, 6α,7β-dihydroxyferruginol (1), 6α,7α-dihydroxyferruginol (2), 6α-hydroxyhinokiol (3), 4α-hydroxy-7-oxo-18-norabieta-8,11,13-trien-4α-ol (4a), 15,16-dehydrosugiol (5), 7-methoxy-6,7-secoabieta-8,11,13-triene-6,12-diol …
View article: Secondary Metabolites with Antimycobacterial Activities from One Actinobacteria: Herbidospora yilanensis
Secondary Metabolites with Antimycobacterial Activities from One Actinobacteria: Herbidospora yilanensis Open
The cultivation of one actinobacteria strain, Herbidospora yilanensis, was isolated from sediment samples collected from Yilan County City in Taiwan, resulting in the isolation of five previously undescribed compounds: herbidosporayilanens…
View article: Secondary Metabolites with Anti-Inflammatory Activities from One Actinobacteria Amycolatopsis taiwanensis
Secondary Metabolites with Anti-Inflammatory Activities from One Actinobacteria Amycolatopsis taiwanensis Open
Phytochemical investigation and chromatographic separation of extracts from one new actinobacteria strain Amycolatopsis taiwanensis that was isolated from soil of Yilan township, in the north of Taiwan, led to the isolation of nine new com…
View article: Saccharpiscinols A–C: Flavans with Potential Anti-Inflammatory Activities from One Actinobacteria Saccharomonospora piscinae
Saccharpiscinols A–C: Flavans with Potential Anti-Inflammatory Activities from One Actinobacteria Saccharomonospora piscinae Open
Phytochemical investigation and chromatographic separation of extracts from the actinobacteria strain Saccharomonospora piscinae that was isolated from dried fishpond sediment of Kouhu township, in the south of Taiwan, led to the isolation…
View article: Investigations into Chemical Components from Monascus purpureus with Photoprotective and Anti-Melanogenic Activities
Investigations into Chemical Components from Monascus purpureus with Photoprotective and Anti-Melanogenic Activities Open
Monascus species are asexually or sexually reproduced homothallic fungi that can produce a red colorant, specifically the so-called red yeast rice or Anka, which is used as a food ingredient in Asia. Traditional experiences of using Monasc…
View article: Rare Chromone Derivatives from the Marine-Derived Penicillium citrinum with Anti-Cancer and Anti-Inflammatory Activities
Rare Chromone Derivatives from the Marine-Derived Penicillium citrinum with Anti-Cancer and Anti-Inflammatory Activities Open
Three new and rare chromone derivatives, epiremisporine C (1), epiremisporine D (2), and epiremisporine E (3), were isolated from marine-derived Penicillium citrinum, together with four known compounds, epiremisporine B (4), penicitrinone …
View article: Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis
Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis Open
Qin Pi (Fraxinus chinensis Roxb.) is commercially used in healthcare products for the improvement of intestinal function and gouty arthritis in many countries. Three new secoiridoid glucosides, (8E)-4′′-O-methylligstroside (1), (8E)-4′′-O-…
View article: Chemical Constituents with GNMT-Promoter-Enhancing and NRF2-Reduction Activities from Taiwan Agarwood Excoecaria formosana
Chemical Constituents with GNMT-Promoter-Enhancing and NRF2-Reduction Activities from Taiwan Agarwood Excoecaria formosana Open
Hepatocellular carcinoma (HCC) is considered to be a silent killer, and was the fourth leading global cause of cancer deaths in 2018. For now, sorafenib is the only approved drug for advanced HCC treatment. The introduction of additional c…
View article: Screening of Azaphilone Derivatives From <i>Monascus pilosus</i>-Fermented Rice (Red Yeast Rice) and Their Evaluation as Nonsteroidal Androgen Receptor Antagonists
Screening of Azaphilone Derivatives From <i>Monascus pilosus</i>-Fermented Rice (Red Yeast Rice) and Their Evaluation as Nonsteroidal Androgen Receptor Antagonists Open
Monascus pilosus BCRC 38093 is a mutant strain of M. pilosus BCRC 38072. The 95% ethanol extract of red yeast rice fermented by M. pilosus BCRC 38093 showed 4 major signals on high performance liquid chromatography (HPLC) examination. The …