Fahu Chen
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View article: Hydroclimatic instability accelerated the socio-political decline of the Tang Dynasty in northern China
Hydroclimatic instability accelerated the socio-political decline of the Tang Dynasty in northern China Open
Extreme flooding and prolonged, intensifying droughts have played a critical role in the rise and collapse of preindustrial states and empires worldwide, triggering cascading impacts such as crop failure, famine, and migration that undermi…
View article: Boosted Regression Trees Machine Learning Method Improves the brGDGT‐Based Climate Reconstruction in Drylands
Boosted Regression Trees Machine Learning Method Improves the brGDGT‐Based Climate Reconstruction in Drylands Open
Branched glycerol dialkyl glycerol tetraethers (brGDGTs), bacterial membrane lipids, are widely used as temperature proxies. Although these proxies are effective for reconstructing past temperatures, brGDGT‐based methods encounter limitati…
View article: The Circulation of Yersinia pestis in Central Eurasia before and during the First Plague Pandemic (Second to Eighth Century CE): Palaeogenetic and Historical Evidence and Sociopolitical, Ecological, and Climatic Factors
The Circulation of Yersinia pestis in Central Eurasia before and during the First Plague Pandemic (Second to Eighth Century CE): Palaeogenetic and Historical Evidence and Sociopolitical, Ecological, and Climatic Factors Open
Modern Yersinia pestis genomes show the greatest diversity of the plague pathogen in Central Eurasia. This region is now widely linked to the origins of the Y. pestis lineages responsible for two historic plague pandemics: one starting wit…
View article: BrGDGT-based palaeothermometer in drylands: the necessity to constrain aridity and salinity as confounding factors to ensure the robustness of calibrations
BrGDGT-based palaeothermometer in drylands: the necessity to constrain aridity and salinity as confounding factors to ensure the robustness of calibrations Open
Past temperature reconstructions offer valuable insights into the impact of climate change on the global climate-human-vegetation system. Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are recognized as effective temperature prox…
View article: Predicting Channel Water Depth: A Multi-Coupling Deep Ensemble Model Approach
Predicting Channel Water Depth: A Multi-Coupling Deep Ensemble Model Approach Open
With global warming and accelerated urbanization, urban flooding became one of the top ten international natural disasters in 2024. In order to accurately and efficiently simulate the impact of upstream river water transport on downstream …
View article: Pronounced methane cycling in northern lakes coincided with a rapid rise in atmospheric CH <sub>4</sub> during the last deglacial warming
Pronounced methane cycling in northern lakes coincided with a rapid rise in atmospheric CH <sub>4</sub> during the last deglacial warming Open
Atmospheric methane concentration (AMC) surged by ~50% during the last deglaciation, with northern (>30°N) sources accounting for ~40% of the rise. However, hypothesized sources including expanding lakes, peatlands, and destabilized permaf…
View article: Gaining water bodies by climate change benefits water crisis mitigation in central Asia
Gaining water bodies by climate change benefits water crisis mitigation in central Asia Open
Central Asia (CA) faces a severe water crisis exemplified by the shrinking Aral Sea. However, little is known about the entire region, particularly the numerous small water bodies that are vulnerable to climate change yet vital for regiona…
View article: Quina lithic technology indicates diverse Late Pleistocene human dynamics in East Asia
Quina lithic technology indicates diverse Late Pleistocene human dynamics in East Asia Open
The Late Pleistocene of Eurasia is key for understanding interactions between early modern humans and different types of archaic human groups. During this period, lithic technology shows more diversity and complexity, likely indicating fle…
View article: Trans-Eurasia Exchange and Silk Road Civilization Development
Trans-Eurasia Exchange and Silk Road Civilization Development Open
The Silk Road (Chinese: 丝绸之路), first popularized by the German geographer Ferdinand von Richthofen in 1877, refers to a network of trade routes that stretched from central China to the Pamir, through central Asi…
View article: Ineffective actions on water scarcity exacerbate the water crisis in West Asia
Ineffective actions on water scarcity exacerbate the water crisis in West Asia Open
Climate change and water availability in arid West Asia are critical to understanding human adaptation to long-term environmental changes. While droughts are well-documented, water availability remains insufficiently quantified. Using high…
View article: Two types of heavy precipitation in the southeastern Tibetan Plateau&#160;
Two types of heavy precipitation in the southeastern Tibetan Plateau  Open
The southeastern Tibetan Plateau (SETP) is the preeminent summer heavy precipitation region within the Tibetan Plateau (TP). However, the large-scale circulation types and dynamics driving summer heavy pre- cipitation in the SETP remain in…
View article: The Quina techno-complex in southwestern China and implications for human environmental adaptation &#160;
The Quina techno-complex in southwestern China and implications for human environmental adaptation   Open
The Middle Paleolithic is a hotly debated issue in China, in particular with the intriguing findings in recent years in both northern and southern China. Here we present a new Middle Paleolithic site named the Longtan site located…
View article: Reconstruction of dust activity using geochemical proxy from cave stalagmite in the northern Taklimakan Desert
Reconstruction of dust activity using geochemical proxy from cave stalagmite in the northern Taklimakan Desert Open
Located in the arid inland of Asia, the eastern part of the Silk Road is marked by certain routes being close to or even crossing large deserts, such as the Taklimakan Desert, one of the largest deserts worldwide. As a result, sand and dus…
View article: Sedimentary Ancient DNA Reveals Further Evidence of Early Settlement Strategies, Pastoralism, and Trade Practices of High-Altitude Populations at the Mabu Co Site on the Tibetan Plateau
Sedimentary Ancient DNA Reveals Further Evidence of Early Settlement Strategies, Pastoralism, and Trade Practices of High-Altitude Populations at the Mabu Co Site on the Tibetan Plateau Open
Sedimentary ancient DNA (sedaDNA) extracted from sediment samples at the high-altitude Marbuco site (4400 meters above sea level) provides critical insights into human-environment interactions. With increasing climate impacts on high-altit…
View article: &#8216;&#8216;Mega-sandwich pattern&#8221; of interdecadal precipitation variations and itsregional manifestation in the Asian summer precipitation region
‘‘Mega-sandwich pattern” of interdecadal precipitation variations and itsregional manifestation in the Asian summer precipitation region Open
The Tibetan Plateau (TP) is an important link between the South Asian monsoon region, the East Asian monsoon region, and the drylands of Central Asia. Climate changes within these regions are dominated by both the monsoon and the westerlie…
View article: Hypothesis of yak domestication based on archaeological and ancient DNA evidence
Hypothesis of yak domestication based on archaeological and ancient DNA evidence Open
Yak (Bos grunniens) has a strong adaptability to the alpine ecological environment, and is also known as the "boat of the plateau" and "omnipotent livestock". The domestication of yaks has provided an important survival basis for human bei…
View article: Chemically Synthesized Phosphorylated Ubiquitin Unlocks Parkin for Activation-Controlled PROTAC Platforms
Chemically Synthesized Phosphorylated Ubiquitin Unlocks Parkin for Activation-Controlled PROTAC Platforms Open
Proteolysis targeting chimeras (PROTACs) have been considered a promising therapeutic strategy, but their application is restricted by the limited number of available E3 ligases. Here, we expanded Parkin, an autoinhibitory E3 whose activit…
View article: Cenozoic evolution of spring persistent rainfall in East Asia and North America driven by paleogeography
Cenozoic evolution of spring persistent rainfall in East Asia and North America driven by paleogeography Open
Spring persistent rainfall is a unique climate phenomenon that prevails in East Asia today, providing precious water resources to this densely populated region. However, its Cenozoic history and underlying mechanisms remain poorly understo…