Chengguo Li
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View article: Prognostic value of Naples prognostic score for locally advanced gastric cancer after neoadjuvant chemoimmunotherapy
Prognostic value of Naples prognostic score for locally advanced gastric cancer after neoadjuvant chemoimmunotherapy Open
NPS is a significant prognostic indicator and can be a reliable predictor of survival in LAGC patients underwent radical resection after NCIT.
View article: Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery
Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery Open
BACKGROUND Coagulation status is closely related to the progression of malignant tumors. In the era of neoadjuvant immunochemotherapy (NICT), the prognostic utility of coagulation indicators in patients with locally advanced gastric cancer…
View article: Combined pan-immune-inflammation value and signet ring cell carcinoma predict pathological complete response and prognosis to neoadjuvant chemoimmunotherapy in locally advanced gastric cancer
Combined pan-immune-inflammation value and signet ring cell carcinoma predict pathological complete response and prognosis to neoadjuvant chemoimmunotherapy in locally advanced gastric cancer Open
Objective To evaluate the predictive value of pan-immune-inflammatory value (PIV) and signet ring cell carcinoma (SRCC) in pathological complete response (pCR) and prognosis in patients with locally advanced gastric cancer (LAGC) receiving…
View article: The utility of ultrasound-guided percutaneous needle biopsy for diagnosis of peripheral pulmonary lesions: A retrospective cohort study
The utility of ultrasound-guided percutaneous needle biopsy for diagnosis of peripheral pulmonary lesions: A retrospective cohort study Open
Objective: The aim of this study was to explore the diagnostic accuracy of ultrasound-guided (US-guided) percutaneous needle biopsy (PNB) and related influencing factors that could provide references for clinicians to improve the diagnosti…
View article: Laparoscopic versus open surgery for rectal neuroendocrine tumors: a multicenter real-world study
Laparoscopic versus open surgery for rectal neuroendocrine tumors: a multicenter real-world study Open
Laparoscopic surgery was associated with improved postoperative outcomes and oncologic prognosis for patients with rectal neuroendocrine tumors ≤ 4 cm; it can serve as a safe and feasible option for radical surgery of rectal neuroendocrine…
View article: Current Status and Future Trends of Green Metallurgical Technology
Current Status and Future Trends of Green Metallurgical Technology Open
Green metallurgical technology, as an environmentally friendly and efficient metallurgical method, is increasingly becoming a global research focus in the metallurgical industry. This paper reviews the definition, essence, historical evolu…
View article: GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience
GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience Open
BACKGROUND There is currently a shortage of accurate, efficient, and precise predictive instruments for rectal neuroendocrine neoplasms (NENs). AIM To develop a predictive model for individuals with rectal NENs (R-NENs) using data from a l…
View article: Laparoscopic Versus Open Surgery for Rectal Neuroendocrine Tumors: A Multicenter Real-World Study
Laparoscopic Versus Open Surgery for Rectal Neuroendocrine Tumors: A Multicenter Real-World Study Open
Background Due to the lack of large sample evidence-based medical studies, the surgical approach for radical resection of rectal neuroendocrine tumors is controversial. Methods We retrospectively collected the medical records of rectal neu…
View article: Long-term outcomes of 1–2 cm rectal neuroendocrine tumors after local excision or radical resection: A population-based multicenter study
Long-term outcomes of 1–2 cm rectal neuroendocrine tumors after local excision or radical resection: A population-based multicenter study Open
R-NETs measuring 1-2 cm generally have a favorable prognosis, and there is no difference in postoperative survival between LE and RR. For patients without lymph node metastasis, LE should be the preferred choice; however, for patients with…
View article: Local Excision Versus Radical Resection for Grade 2 Rectal Neuroendocrine Tumors: A Multicenter Propensity Score-Matched Analysis
Local Excision Versus Radical Resection for Grade 2 Rectal Neuroendocrine Tumors: A Multicenter Propensity Score-Matched Analysis Open
BACKGROUND: Studies on grade 2 rectal neuroendocrine tumors are limited, and the optimal treatment for these tumors is not well established. OBJECTIVE: We aimed to compare the oncologic results of local excision versus radical resection fo…
View article: ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer Open
Tumor metastasis severely limits the prognosis of gastric cancer patients. RNA-binding proteins (RBPs) are crucial in tumor metastasis, yet there is limited research into their involvement in gastric cancer. Here, we found that ESRP1, a RB…
View article: Risk of stroke in patients with psoriatic disease: a systematic review and meta-analysis
Risk of stroke in patients with psoriatic disease: a systematic review and meta-analysis Open
Stroke is a neurologic disease caused by sudden disturbance of cerebral blood circulation. Studies have shown that patients with psoriatic disease (PsD) (psoriasis and psoriatic arthritis (PsA)) may have an increased risk of stroke, but th…
View article: Lymph node ratio and hematological parameters predict relapse-free survival in patients with high grade rectal neuroendocrine neoplasms after radical resection: a multicenter prognostic study
Lymph node ratio and hematological parameters predict relapse-free survival in patients with high grade rectal neuroendocrine neoplasms after radical resection: a multicenter prognostic study Open
Background The prognostic nutritional index (PNI), alkaline phosphatase (ALP), and lymph node ratio (LNR) are reportedly related to prognosis. The aim of this study was to elucidate the clinical importance of the LNR and hematological para…
View article: Combination of <scp>PARP</scp> inhibitor and <scp>CDK4</scp>/6 inhibitor modulates <scp>cGAS</scp>/<scp>STING‐</scp>dependent therapy‐induced senescence and provides “one‐two punch” opportunity with <scp>anti‐PD‐L1</scp> therapy in colorectal cancer
Combination of <span>PARP</span> inhibitor and <span>CDK4</span>/6 inhibitor modulates <span>cGAS</span>/<span>STING‐</span>dependent therapy‐induced senescence and provides “one‐two punch” opportunity with <span>anti‐PD‐L1</span> therapy in colorectal cancer Open
Although PARP inhibitor (PARPi) has been proven to be a promising anticancer drug in cancer patients harboring BRCA1/2 mutation, it provides limited clinical benefit in colorectal cancer patients with a low prevalence of BRCA1/2 mutations.…
View article: Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis
Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis Open
Oxaliplatin is widely used in chemotherapy for colorectal cancer (CRC), but its sensitivity has become a major obstacle to limiting efficacy. Many literatures reported that Nrf2 activation promoted tumor chemoresistance. In this study, we …
View article: Lymph node ratio and hematological parameters predict relapse-free survival in Patients With high grade rectal neuroendocrine neoplasms after radical resection: A multicenter prognostic study
Lymph node ratio and hematological parameters predict relapse-free survival in Patients With high grade rectal neuroendocrine neoplasms after radical resection: A multicenter prognostic study Open
Background The prognostic nutritional index (PNI), alkaline phosphatase (ALP) and lymph node ratio (LNR) are reportedly related to prognosis. The aim of this study was to elucidate the clinical importance of the LNR and hematological param…
View article: 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to promote cuproptosis in colorectal cancer
4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to promote cuproptosis in colorectal cancer Open
Cuproptosis, a novel copper-induced cell death pathway, is linked to mitochondrial respiration and mediated by protein lipoylation. The discovery of cuproptosis unfolds new areas of investigation, particularly in cancers. The present study…
View article: Study of dry etched N-polar (Al)GaN surfaces obtained by inductively coupled plasma etching
Study of dry etched N-polar (Al)GaN surfaces obtained by inductively coupled plasma etching Open
We report the Cl-based inductively coupled plasma etching of N-polar Al(Ga)N layers obtained from layer transfer. It is found that debris appeared on the etched N-polar surface after exposing in air for a short period whereas the etched Al…
View article: Evaluation of On-Board Sensor-Based NOx emissions from the heavy-duty vehicles in an inspection and Maintenance program
Evaluation of On-Board Sensor-Based NOx emissions from the heavy-duty vehicles in an inspection and Maintenance program Open
Heavy-duty diesel vehicles (HDDVs) are important sources of urban nitrogen oxides (NOx) in an actual application for environmental compliance. The remote on-board sensing (OBS) is a cost-effective emission reduction approach for HDDVs. NOx…
View article: Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response Open
Inflammatory bowel disease (IBD) is a chronic relapsing gastrointestinal disorder, while the treatment effect is not satisfactory. Immune responsive gene 1 (IRG1) is a highly expressed gene in macrophage in response to inflammatory respons…
View article: MUS81 Inhibition Enhances the Anticancer Efficacy of Talazoparib by Impairing ATR/CHK1 Signaling Pathway in Gastric Cancer
MUS81 Inhibition Enhances the Anticancer Efficacy of Talazoparib by Impairing ATR/CHK1 Signaling Pathway in Gastric Cancer Open
MUS81 is a critical endonuclease involved in heterodimer formation with Eme1/Mms4 and an important DNA damage repair regulatory molecule. Our previous study suggested that MUS81 was overexpressed and its high expression was positively corr…
View article: Biomechanical effect of metal augment and bone graft on cup stability for acetabular reconstruction of total hip arthroplasty in hip dysplasia: a finite element analysis
Biomechanical effect of metal augment and bone graft on cup stability for acetabular reconstruction of total hip arthroplasty in hip dysplasia: a finite element analysis Open
Background Different methods of acetabular reconstruction with total hip arthroplasty (THA) for Crowe II and III of adult developmental dysplasia of the hip (DDH) acetabular bone defect have been implemented clinically. However, the biomec…
View article: Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis Open
4-Octyl itaconate (OI) is a novel anti-inflammatory metabolite that exerts protective effects in many various disease models. However, its function in autoimmune hepatitis- (AIH-) associated hepatic injury has not been investigated. In thi…
View article: Antifungal Volatile Organic Compounds from Streptomyces setonii WY228 Control Black Spot Disease of Sweet Potato
Antifungal Volatile Organic Compounds from Streptomyces setonii WY228 Control Black Spot Disease of Sweet Potato Open
Black spot disease caused by Ceratocystis fimbriata has caused huge economic losses to worldwide sweet potato production. At present, the control of C. fimbriata mainly depends on toxic fungicides, and there is a lack of effective alternat…
View article: 4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis Open
Introduction: Sepsis is a major global health challenge with high mortality rates and no effective treatment. Recent studies have suggested that sepsis may be associated with immune system dysfunction. Itaconate may exert anti-inflammatory…
View article: Diversity of Endophytic Bacteria Associated with Different Cultivars of Medicinal Plant Arctium Lappa L. and Their Potential for Host Plant Growth Promoting
Diversity of Endophytic Bacteria Associated with Different Cultivars of Medicinal Plant Arctium Lappa L. and Their Potential for Host Plant Growth Promoting Open
Purpose Arctium lappa L. is one of the medicinal and food homologous plants in China, which is rich in nutrients and medicinal ingredients. The use of plant growth promoting (PGP) endophytic bacteria is a useful alternative in agricultural…
View article: Green Synthesized Gold Nanoparticles Using Viola betonicifolia Leaves Extract: Characterization, Antimicrobial, Antioxidant, and Cytobiocompatible Activities
Green Synthesized Gold Nanoparticles Using Viola betonicifolia Leaves Extract: Characterization, Antimicrobial, Antioxidant, and Cytobiocompatible Activities Open
Thus, our study establishes a novel ecologically acceptable route for nanomaterials' fabrication with increased and/or extra medicinal functions derived from their herbal origins.