Chenhao Zhou
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View article: DysUFMylation of SREBP1 Promotes the Progression of Hepatocellular Carcinoma by Reprogramming Lipid Metabolism
DysUFMylation of SREBP1 Promotes the Progression of Hepatocellular Carcinoma by Reprogramming Lipid Metabolism Open
UFMylation is a critical posttranslational modification that destabilizes SREBP1, and its dysregulation contributes to HCC progression. Targeting the UFMylation-SREBP1 axis, particularly through Fatostatin and Lenvatinib combination therap…
View article: SLFN11, far from being limited to responding to cancer DNA damage
SLFN11, far from being limited to responding to cancer DNA damage Open
View article: Integrative analysis of lactylation related genes in prostate cancer: unveiling heterogeneity through single-cell RNA-seq, bulk RNA-seq and machine learning
Integrative analysis of lactylation related genes in prostate cancer: unveiling heterogeneity through single-cell RNA-seq, bulk RNA-seq and machine learning Open
Introduction Lactylation, a post-translational modification characterized by the attachment of lactate to protein lysine residues on proteins, plays a pivotal role in cancer progression and immune evasion. However, its implications in immu…
View article: Genetic Diversity and Population Structure Analysis of Luhua chickens Based on Genome-Wide Markers
Genetic Diversity and Population Structure Analysis of Luhua chickens Based on Genome-Wide Markers Open
The Luhua chicken is an outstanding local breed in China that has been placed under conservation due to the impact of specialized breeding and the widespread adoption of commercial varieties. As such, this study analyzed reproductive trait…
View article: User-cooperative dynamic resource allocation for backscatter-aided wireless-powered MEC network
User-cooperative dynamic resource allocation for backscatter-aided wireless-powered MEC network Open
View article: RNase1-driven ALK-activation is an oncogenic driver and therapeutic target in non-small cell lung cancer
RNase1-driven ALK-activation is an oncogenic driver and therapeutic target in non-small cell lung cancer Open
View article: The Role of Post-Translational Modifications in Necroptosis
The Role of Post-Translational Modifications in Necroptosis Open
Necroptosis, a distinct form of regulated necrosis implicated in various human pathologies, is orchestrated through sophisticated signaling pathways. During this process, cells undergoing necroptosis exhibit characteristic necrotic morphol…
View article: Paleo-Asian Ocean Ridge Subduction: Evidence from Volcanic Rocks in the Fuyun–Qinghe Area, Southern Margin of the Chinese Altay
Paleo-Asian Ocean Ridge Subduction: Evidence from Volcanic Rocks in the Fuyun–Qinghe Area, Southern Margin of the Chinese Altay Open
The Chinese Altay is located in the western segment of the Central Asian Orogenic Belt (CAOB) and preserves critical records of the Paleo-Asian Ocean (PAO) Plate evolution during the Paleozoic era. This region also hosts significant minera…
View article: Correction for: The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection
Correction for: The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection Open
View article: Multi-Level Metalized Pbo Composite Fabric for Polar Extreme Environments: Integrating Electromagnetic Protection, Stable Electric Thermal Conversion, and High-Strength
Multi-Level Metalized Pbo Composite Fabric for Polar Extreme Environments: Integrating Electromagnetic Protection, Stable Electric Thermal Conversion, and High-Strength Open
View article: Toxicological Research of Evodiae Decoction
Toxicological Research of Evodiae Decoction Open
View article: Multi-Level Metalized Pbo Composite Fabric for Polar Extreme Environments: Integrating Electromagnetic Protection, Stable Electric Thermal Conversion, and High-Strength
Multi-Level Metalized Pbo Composite Fabric for Polar Extreme Environments: Integrating Electromagnetic Protection, Stable Electric Thermal Conversion, and High-Strength Open
View article: Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis
Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis Open
View article: Optimizing Transmit Power for User-Cooperative Backscatter-Assisted NOMA-MEC: A Green IoT Perspective
Optimizing Transmit Power for User-Cooperative Backscatter-Assisted NOMA-MEC: A Green IoT Perspective Open
Non-orthogonal multiple access (NOMA) enables the parallel offloading of multiuser tasks, effectively enhancing throughput and reducing latency. Backscatter communication, which passively reflects radio frequency (RF) signals, improves ene…
View article: User Cooperation-Enhanced Dynamic Resource Allocation for Throughput Maximization in NOMA-Enabled Wireless Powered MEC
User Cooperation-Enhanced Dynamic Resource Allocation for Throughput Maximization in NOMA-Enabled Wireless Powered MEC Open
View article: N-acetyltransferase 10 as a novel prognostic biomarker in papillary renal cell carcinoma: a machine learning and experimental validation study
N-acetyltransferase 10 as a novel prognostic biomarker in papillary renal cell carcinoma: a machine learning and experimental validation study Open
Our findings suggest that NAT10 is aberrantly expressed in pRCC, is associated with poor prognosis, and contributes to pRCC progression through multiple pathways, offering new insights into the personalized treatment of patients wit…
View article: WWOX tuning of oleic acid signaling orchestrates immunosuppressive macrophage polarization and sensitizes hepatocellular carcinoma to immunotherapy
WWOX tuning of oleic acid signaling orchestrates immunosuppressive macrophage polarization and sensitizes hepatocellular carcinoma to immunotherapy Open
Background Immune checkpoint inhibitors (ICIs) are therapeutically effective for hepatocellular carcinoma (HCC) but are individually selective. This study examined the role of specific common fragile sites (CFSs) related gene in HCC immuno…
View article: Optimizing Transmit Power for User-Cooperative Backscatter-assisted NOMA-MEC: A Green IoT Perspective
Optimizing Transmit Power for User-Cooperative Backscatter-assisted NOMA-MEC: A Green IoT Perspective Open
Non-orthogonal multiple access (NOMA) enables the parallel offloading of multiuser tasks, effectively enhancing throughput and reducing latency. Backscatter communication, which passively reflects radio frequency (RF) signals, improves ene…
View article: Brain-to-brain synchrony increased during interpersonal touch in romantic lovers: an EEG-based hyperscanning study
Brain-to-brain synchrony increased during interpersonal touch in romantic lovers: an EEG-based hyperscanning study Open
Background Interpersonal touch is an essential element of human social life. It’s unclear whether the neural patterns of interpersonal touch are specific to intimate relationships or generally apply to other social relationships. Romantic …
View article: The Prognostic Significance of CTSV Expression in Patients with Hepatocellular Carcinoma
The Prognostic Significance of CTSV Expression in Patients with Hepatocellular Carcinoma Open
CTSV serves as a standalone negative prognostic indicator and possesses clinical significance in HCC.
View article: sEV-mediated lipid droplets transferred from bone marrow adipocytes promote ferroptosis and impair osteoblast function
sEV-mediated lipid droplets transferred from bone marrow adipocytes promote ferroptosis and impair osteoblast function Open
Osteoporosis is linked to increased bone marrow adipocyte (BMAd) proliferation, which displaces bone-forming cells and alters the local environment. The impact of BMAd lipid droplets on bone health and osteoblast function remains unclear. …
View article: User-Cooperative Dynamic Resource Allocation for Backscatter-Aided Wireless-Powered MEC Network
User-Cooperative Dynamic Resource Allocation for Backscatter-Aided Wireless-Powered MEC Network Open
Backscatter communication, which transmits information by passively reflecting radio frequency (RF) signals, has become a focal point of interest due to its potential to significantly enhance the energy efficiency of Wireless Power Mobile …
View article: Methylome and transcriptome joint analyses identify differentially expressed genes based on purebred and crossbred Tianjin-monkey Chicken
Methylome and transcriptome joint analyses identify differentially expressed genes based on purebred and crossbred Tianjin-monkey Chicken Open
Tianjin-monkey Chicken is a locally bred naked neck poultry with limited population size. Herein, we intended to identify potential breed-related genes based on methylome and transcriptome analyses. Tianjin-monkey Chicken and Hy-line Brown…
View article: User-Cooperative Dynamic Resource Allocation for Backscatter-Aided Wireless-Powered MEC Network
User-Cooperative Dynamic Resource Allocation for Backscatter-Aided Wireless-Powered MEC Network Open
Backscatter communication, which transmits information by passively reflecting radio 1 frequency (RF) signals, has become a focal point of interest due to its potential to significantly enhance 2 the energy efficiency of Wireless Power Mob…
View article: Maximizing Computation Rate for Sustainable Wireless-Powered MEC Network: An Efficient Dynamic Task Offloading Algorithm with User Assistance
Maximizing Computation Rate for Sustainable Wireless-Powered MEC Network: An Efficient Dynamic Task Offloading Algorithm with User Assistance Open
In the Internet of Things (IoT) era, Mobile Edge Computing (MEC) significantly enhances the efficiency of smart devices but is limited by battery life issues. Wireless Power Transfer (WPT) addresses this issue by providing a stable energy …
View article: Energy-Efficient Task Offloading in Wireless-Powered MEC: A Dynamic and Cooperative Approach
Energy-Efficient Task Offloading in Wireless-Powered MEC: A Dynamic and Cooperative Approach Open
Mobile Edge Computing (MEC) integrated with Wireless Power Transfer (WPT) is emerging as a promising solution to reduce task delays and extend the battery life of Mobile Devices (MDs). However, maximizing the long-term energy efficiency (E…
View article: Maximizing Computation Rate for Sustainable Wireless Powered MEC network: An Efficient Dynamic Task Offloading Algorithm with User Assistance
Maximizing Computation Rate for Sustainable Wireless Powered MEC network: An Efficient Dynamic Task Offloading Algorithm with User Assistance Open
In the Internet of Things (IoT) era, Mobile Edge Computing (MEC) significantly enhances the efficiency of smart devices but is limited by battery life issues. Wireless Power Transfer (WPT) addresses this issue by providing a stable energy …
View article: <i>FGFR2</i> fusion/rearrangement is associated with favorable prognosis and immunoactivation in patients with intrahepatic cholangiocarcinoma
<i>FGFR2</i> fusion/rearrangement is associated with favorable prognosis and immunoactivation in patients with intrahepatic cholangiocarcinoma Open
Increasing evidence highlights that fibroblast growth factor receptor 2 (FGFR2) fusion/rearrangement shows important therapeutic value for patients with intrahepatic cholangiocarcinoma (ICC). This study aims to explore the association of F…
View article: Energy-Efficient Task Offloading in Wireless-Powered MEC: A Dynamic and Cooperative Approach
Energy-Efficient Task Offloading in Wireless-Powered MEC: A Dynamic and Cooperative Approach Open
Mobile Edge Computing (MEC) integrated with Wireless Power Transfer (WPT) is emerging as a promising solution to reduce task delays and extend the battery life of Mobile Devices (MDs). Cooperative user communication, or relay technology, e…
View article: Data from Repolarization of Immunosuppressive Macrophages by Targeting SLAMF7-Regulated CCL2 Signaling Sensitizes Hepatocellular Carcinoma to Immunotherapy
Data from Repolarization of Immunosuppressive Macrophages by Targeting SLAMF7-Regulated CCL2 Signaling Sensitizes Hepatocellular Carcinoma to Immunotherapy Open
Immune checkpoint inhibitors have limited efficacy in hepatocellular carcinoma (HCC). Macrophages are the most abundant immune cells in HCC, suggesting that a better understanding of the intrinsic processes by which tumor cells regulate ma…