Chengkui Zhao
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View article: Immune status assessment based on plasma proteomics with meta graph convolutional networks
Immune status assessment based on plasma proteomics with meta graph convolutional networks Open
Plasma proteins, especially immune-related proteins, are vital for assessing immune health and predicting disease risks. Despite their significance, the link between these proteins and systemic immune function remains unclear. To bridge th…
View article: Crgnn: Causal and Residual Graph Neural Network for Speech Emotion Recognition in Conversation
Crgnn: Causal and Residual Graph Neural Network for Speech Emotion Recognition in Conversation Open
View article: BertTCR: a Bert-based deep learning framework for predicting cancer-related immune status based on T cell receptor repertoire
BertTCR: a Bert-based deep learning framework for predicting cancer-related immune status based on T cell receptor repertoire Open
The T cell receptor (TCR) repertoire is pivotal to the human immune system, and understanding its nuances can significantly enhance our ability to forecast cancer-related immune responses. However, existing methods often overlook the intra…
View article: PrCRS: a prediction model of severe CRS in CAR-T therapy based on transfer learning
PrCRS: a prediction model of severe CRS in CAR-T therapy based on transfer learning Open
Background CAR-T cell therapy represents a novel approach for the treatment of hematologic malignancies and solid tumors. However, its implementation is accompanied by the emergence of potentially life-threatening adverse events known as c…
View article: Meta-DHGNN: method for CRS-related cytokines analysis in CAR-T therapy based on meta-learning directed heterogeneous graph neural network
Meta-DHGNN: method for CRS-related cytokines analysis in CAR-T therapy based on meta-learning directed heterogeneous graph neural network Open
Chimeric antigen receptor T-cell (CAR-T) immunotherapy, a novel approach for treating blood cancer, is associated with the production of cytokine release syndrome (CRS), which poses significant safety concerns for patients. Currently, ther…
View article: Corrigendum: Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells
Corrigendum: Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells Open
[This corrects the article DOI: 10.3389/fimmu.2023.1273507.].
View article: A Universal Strategy for Smoothing Deceleration in Deep Graph Neural Networks
A Universal Strategy for Smoothing Deceleration in Deep Graph Neural Networks Open
View article: A score-based method of immune status evaluation for healthy individuals with complete blood cell counts
A score-based method of immune status evaluation for healthy individuals with complete blood cell counts Open
Background With the COVID-19 outbreak, an increasing number of individuals are concerned about their health, particularly their immune status. However, as of now, there is no available algorithm that effectively assesses the immune status …
View article: Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells
Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells Open
Introduction CAR-T cell therapy is a novel approach in the treatment of hematological tumors. However, it is associated with life-threatening side effects, such as the severe cytokine release syndrome (sCRS). Therefore, predicting the occu…
View article: Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk
Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk Open
View article: Methods for predicting single-cell miRNA in breast cancer
Methods for predicting single-cell miRNA in breast cancer Open
It has been demonstrated that miRNAs are involved in many biological processes including cell proliferation and differentiation, apoptosis, and stress responses. Although single-cell RNA sequencing technology is prevailing nowadays, it sti…
View article: Additional file 2 of Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk
Additional file 2 of Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk Open
Additional file 2. Interactions between cytokines used in the study.
View article: Additional file 1 of Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk
Additional file 1 of Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk Open
Additional file 1. Cytokines used in the study.
View article: Prediction of functional microexons by transfer learning
Prediction of functional microexons by transfer learning Open