Chengliang Yang
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View article: The Mechanism of Microstructure Refinement and the Synergistic Strength–Ductility Enhancement in Al–Zn–Mg–Cu Alloys Processed by Continuous Rheo-Extrusion
The Mechanism of Microstructure Refinement and the Synergistic Strength–Ductility Enhancement in Al–Zn–Mg–Cu Alloys Processed by Continuous Rheo-Extrusion Open
Al–Zn–Mg–Cu alloys are well known for their outstanding strength, toughness, and corrosion resistance, arising from the balanced addition of Mg, Zn, and Cu. However, conventional casting methods often lead to grain boundary segregation and…
View article: Association between tacrolimus blood levels and biopsy-proven acute cellular rejection in adult heart transplant recipients
Association between tacrolimus blood levels and biopsy-proven acute cellular rejection in adult heart transplant recipients Open
View article: Identifying Potential Vulnerability to Long COVID Through Global‐to‐Local Inequalities in Years Lived With Disability Attributed to COVID‐19, 2020–2021, Across 920 Locations
Identifying Potential Vulnerability to Long COVID Through Global‐to‐Local Inequalities in Years Lived With Disability Attributed to COVID‐19, 2020–2021, Across 920 Locations Open
The COVID‐19 pandemic has reshaped global health; however, the long‐term burden of long COVID remains poorly understood, especially in low‐ and middle‐income countries (LMICs), where limited surveillance and data gaps may obscure a substan…
View article: Cardiac adverse events associated with remdesivir in COVID-19 patients: a systematic review and meta-analysis of randomised controlled trials
Cardiac adverse events associated with remdesivir in COVID-19 patients: a systematic review and meta-analysis of randomised controlled trials Open
Objectives To evaluate whether remdesivir is associated with cardiac adverse events (CAEs), addressing concerns raised by basic experiments, clinical case reports and observational studies. Design Systematic review and meta-analysis. Data …
View article: Global, Regional, National, and Local Burden of COVID‐19 With Inequality Analysis Across 920 Locations, 2020–2021
Global, Regional, National, and Local Burden of COVID‐19 With Inequality Analysis Across 920 Locations, 2020–2021 Open
Although the COVID‐19 pandemic has profoundly reshaped global health systems, a comprehensive and standardized quantification of its direct health burden across multiple spatial scales, particularly during its initial and most severe phase…
View article: PTPRC as a pan-cancer biomarker: Prognostic significance and immune microenvironment interactions
PTPRC as a pan-cancer biomarker: Prognostic significance and immune microenvironment interactions Open
This study investigated the role of Protein Tyrosine Phosphatase Receptor type C (PTPRC) in various cancers using bioinformatics analyses and experimental validation. We analyzed public databases (TIMER2.0, GEPIA2, cBioPortal) and single-c…
View article: Stigmasterol, a Major Component of Cornus Officinalis, Ameliorates Osteoporosis in Diabetes Mellitus Effects by Increasing Bone Mineral Density
Stigmasterol, a Major Component of Cornus Officinalis, Ameliorates Osteoporosis in Diabetes Mellitus Effects by Increasing Bone Mineral Density Open
STG appears to alleviate osteoporosis in diabetes by improving bone microstructure, promoting bone formation, and reducing bone resorption, indicating its potential as a therapeutic option for managing osteoporosis.
View article: Analysis on Microstructure and Corrosion Resistance of 3003 Al Alloy at Various Twin-Roll Casting Temperatures
Analysis on Microstructure and Corrosion Resistance of 3003 Al Alloy at Various Twin-Roll Casting Temperatures Open
View article: Mechanism of enhanced corrosion resistance in 3003 aluminum alloy by discontinuous secondary phases induced via twin-roll casting temperature
Mechanism of enhanced corrosion resistance in 3003 aluminum alloy by discontinuous secondary phases induced via twin-roll casting temperature Open
View article: Bioinformatics analysis reveals VEGFC’s prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration
Bioinformatics analysis reveals VEGFC’s prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration Open
VEGFC may serve as an independent prognostic factor and potential immunotherapeutic target in HNSCC, offering insights into patient risk stratification and personalized treatment strategies.
View article: Channel screw and W-shaped angular plate fixation of complexposterior acetabular fractures based on x-ray diagnostics
Channel screw and W-shaped angular plate fixation of complexposterior acetabular fractures based on x-ray diagnostics Open
To investigate the surgical technique and clinical effect of cylindrical channel screw and AW-shaped Angle plate in the treatment of complex posterior acetabular fractures. This paper retrospectively analyzed the data of 36 patients with c…
View article: Revisiting Medicaid’s impact on cardiovascular risk
Revisiting Medicaid’s impact on cardiovascular risk Open
Study shows the potential of Medicaid to improve cardiovascular health for specific subpopulations
View article: Multi‐level insights into the immuno‐oncology‐microbiome axis: From biotechnology to novel therapies
Multi‐level insights into the immuno‐oncology‐microbiome axis: From biotechnology to novel therapies Open
The multifaceted interactions among the immune system, cancer cells and microbial components have established a novel concept of the immuno-oncology-microbiome (IOM) axis. Microbiome sequencing technologies have played a pivotal role in no…
View article: High entropy component-induced nanoscale shear banding and twinning enhance Ti6Al4V alloy surface properties
High entropy component-induced nanoscale shear banding and twinning enhance Ti6Al4V alloy surface properties Open
High-entropy alloys (HEAs) present unique advantages in surface modification due to their stable mixed-state
\nstructures and resistance to intermetallic compound formation. This study investigates the surface modification
\nbehavior of eq…
View article: Preoperative sequential chemotherapy and hypofractionated radiotherapy combined with comprehensive surgical resection for high-risk soft tissue sarcomas: a retrospective study
Preoperative sequential chemotherapy and hypofractionated radiotherapy combined with comprehensive surgical resection for high-risk soft tissue sarcomas: a retrospective study Open
Introduction The management of soft tissue sarcomas presents considerable therapeutic challenges. This study was designed to assess the efficacy of neoadjuvant sequential chemotherapy and hypofractionated radiotherapy in conjunction with e…
View article: Donor-specific graft injury in solid organ transplantation: potential mechanisms and therapeutic strategies
Donor-specific graft injury in solid organ transplantation: potential mechanisms and therapeutic strategies Open
View article: Bioinformatics analysis reveals the key factors affecting the progress of osteoporosis
Bioinformatics analysis reveals the key factors affecting the progress of osteoporosis Open
The incidence rate of osteoporosis is high, and patients usually have decreased bone density and increased risk of fracture, which seriously affects their quality of life. This study aims to reveal key biomarkers that affect the progressio…
View article: Consolidation chemotherapy after definitive concurrent chemoradiotherapy in patients with inoperable esophageal squamous cell carcinoma: a multicenter non-inferiority phase III randomized clinical trial
Consolidation chemotherapy after definitive concurrent chemoradiotherapy in patients with inoperable esophageal squamous cell carcinoma: a multicenter non-inferiority phase III randomized clinical trial Open
Background Definitive concurrent chemoradiotherapy (dCCRT) is the gold standard for the treatment of locally advanced esophageal squamous cell carcinoma (ESCC). However, the potential benefits of consolidation chemotherapy after dCCRT in p…
View article: Unravelling long COVID: insights from proteomics and considerations for comprehensive understanding
Unravelling long COVID: insights from proteomics and considerations for comprehensive understanding Open
Long COVID, characterized by persistent symptoms, lacks clear diagnostic and treatment approaches due to uncertain underlying mechanisms. Gu and colleagues delve into the proteomic landscape of COVID-19 survivors over two years, offering i…
View article: Preoperative Sequential Chemotherapy and hypofractionated Radiotherapy Combined with Comprehensive Surgical Resection for High-Risk Soft Tissue Sarcomas: A Retrospective Study
Preoperative Sequential Chemotherapy and hypofractionated Radiotherapy Combined with Comprehensive Surgical Resection for High-Risk Soft Tissue Sarcomas: A Retrospective Study Open
Introduction: The management of soft tissue sarcomas presents considerable therapeutic challenges. This study was designed to assess the efficacy of neoadjuvant sequential chemotherapy and hypofractionated radiotherapy in conjunction with …
View article: PP2 alleviates the progression of osteoarthritis by inhibiting Wnt/β-catenin and activating TGF-β/Smad signaling
PP2 alleviates the progression of osteoarthritis by inhibiting Wnt/β-catenin and activating TGF-β/Smad signaling Open
Our data indicate that targeting Src with PP2 protected against cartilage destruction in an OA mouse model by inhibiting Wnt/β-catenin and activating TGF-β/Smad signaling, suggesting that Src may be a potential therapeutic target for OA tr…
View article: Association of SARS-CoV-2 infection and persistence with long COVID
Association of SARS-CoV-2 infection and persistence with long COVID Open
View article: Cellular and molecular biomarkers of long COVID: a scoping review
Cellular and molecular biomarkers of long COVID: a scoping review Open
Dr. Tebbutt has received funding from the Canadian Institutes of Health Research (177747) to conduct this work. The funding source was not involved in this scoping review, or in the decision to submit this manuscript for publication.
View article: Long COVID: the next public health crisis is already on its way
Long COVID: the next public health crisis is already on its way Open
View article: Pp2 Alleviates the Progression of Osteoarthritis by Inhibiting Wnt/Β-Catenin and Activating Tgf- Β/Smad Signaling
Pp2 Alleviates the Progression of Osteoarthritis by Inhibiting Wnt/Β-Catenin and Activating Tgf- Β/Smad Signaling Open
View article: Titanium Composite Coated with DNA Hydrogel Loaded with Antimicrobial Peptide Tcp-25 for Bacterial Infection Inhibition
Titanium Composite Coated with DNA Hydrogel Loaded with Antimicrobial Peptide Tcp-25 for Bacterial Infection Inhibition Open
View article: Retraction: Acellularized spinal cord scaffolds incorporating bpV(pic)/PLGA microspheres promote axonal regeneration and functional recovery after spinal cord injury
Retraction: Acellularized spinal cord scaffolds incorporating bpV(pic)/PLGA microspheres promote axonal regeneration and functional recovery after spinal cord injury Open
Retraction of ‘Acellularized spinal cord scaffolds incorporating bpV(pic)/PLGA microspheres promote axonal regeneration and functional recovery after spinal cord injury’ by Jia Liu et al. , RSC Adv. , 2020, 10 , 18677–18686, https://doi.or…
View article: Double crosslinked biomimetic composite hydrogels containing topographical cues and WAY-316606 induce neural tissue regeneration and functional recovery after spinal cord injury
Double crosslinked biomimetic composite hydrogels containing topographical cues and WAY-316606 induce neural tissue regeneration and functional recovery after spinal cord injury Open
View article: Omicron variants of SARS-CoV-2 and long COVID
Omicron variants of SARS-CoV-2 and long COVID Open
Understanding the epidemiology of long COVID and emerging variants has significant public-health implications as physical interventions and restrictions that help limit viral spread are eased globally. Here, we provide rationales for the n…
View article: Error assessment and correction for extrusion- based bioprinting using computer vision method
Error assessment and correction for extrusion- based bioprinting using computer vision method Open
Bioprinting offers a new approach to addressing the organ shortage crisis. Despite recent technological advances, insufficient printing resolution continues to be one of the reasons that impede the development of bioprinting. Normally, mac…