Chengming Ding
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View article: Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma [Retraction]
Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma [Retraction] Open
[This retracts the article DOI: 10.2147/IJN.S377080.].
View article: The Effectiveness of Virtual-Real Fusion Teaching Models in Clinical Skills Training: A Randomized -Controlled Trial Comparing Touch Surgery and Traditional Teaching Aids for Thoracentesis
The Effectiveness of Virtual-Real Fusion Teaching Models in Clinical Skills Training: A Randomized -Controlled Trial Comparing Touch Surgery and Traditional Teaching Aids for Thoracentesis Open
Traditional clinical skills training exhibits inherent limitations. This study systematically examines the comparative efficacy of Touch Surgery-based virtual-real integrated training versus conventional teaching aids in thoracentesis proc…
View article: Untargeted metabolomics-based elucidation of metabolic reprogramming mechanisms and pathways following aortic dissection surgery
Untargeted metabolomics-based elucidation of metabolic reprogramming mechanisms and pathways following aortic dissection surgery Open
View article: Establishment and validation of systemic inflammatory index model and risk assessment of PVT in cirrhosis after splenectomy—a retrospective study
Establishment and validation of systemic inflammatory index model and risk assessment of PVT in cirrhosis after splenectomy—a retrospective study Open
Objective The study aimed to create and validate a straightforward nomogram to predict portal vein thrombosis (PVT) in cirrhotic patient post-splenectomy, and investigate the predictive potential of systemic inflammation markers. One objec…
View article: Focusing on CD8+ T-cell phenotypes: improving solid tumor therapy
Focusing on CD8+ T-cell phenotypes: improving solid tumor therapy Open
Vigorous CD8 + T cells play a crucial role in recognizing tumor cells and combating solid tumors. How T cells efficiently recognize and target tumor antigens, and how they maintain the activity in the “rejection” of solid tumor microenviro…
View article: CircPAPPA2 plays a role in preeclampsia pathogenesis via regulation of the miR-942/miR-5006-3p
CircPAPPA2 plays a role in preeclampsia pathogenesis via regulation of the miR-942/miR-5006-3p Open
C ircRNAs are a class of endogenous non-coding RNAs implicated in the pathogenesis of many pregnancy related diseases, one of which is pre-eclampsia (PE). This study aims to investigate the role of CircPAPPA2 (circbase ID: hsa_circ_0015382…
View article: Advances in crosstalk among innate immune pathways activated by mitochondrial DNA
Advances in crosstalk among innate immune pathways activated by mitochondrial DNA Open
View article: Improving Circulatory Support in Cases of Acute DeBakey Type I Aortic Dissection: A Novel Arterial Cannulation Approach and Its Effects on Perfusion and Minimizing Complications
Improving Circulatory Support in Cases of Acute DeBakey Type I Aortic Dissection: A Novel Arterial Cannulation Approach and Its Effects on Perfusion and Minimizing Complications Open
Objective . Proposing a novel arterial cannulation technique for acute DeBakey type I aortic dissection with severe aortic arch and branch involvement to enhance CPB effectiveness and reduce organ malperfusion complications. Methods . The …
View article: Dietary Supplementation with Omega‐3 PUFAs Modulates Gut Microbiota and Protects the Intestinal Barrier in Senescence‐Accelerated Mice
Dietary Supplementation with Omega‐3 PUFAs Modulates Gut Microbiota and Protects the Intestinal Barrier in Senescence‐Accelerated Mice Open
Intestinal mucosal barrier aging is a major cause of the occurrence and development of many chronic diseases in older adults and is closely associated with gut microbiota. However, it remains unclear whether exogenous supplementation with …
View article: MiR-150-5p contributes to unexplained recurrent spontaneous abortion by targeting VEGFA and downregulating the PI3K/AKT/mTOR signaling pathway
MiR-150-5p contributes to unexplained recurrent spontaneous abortion by targeting VEGFA and downregulating the PI3K/AKT/mTOR signaling pathway Open
Purpose The purpose of this study is to investigate the function of miR-150-5p in URSA. Method Twenty-six chorionic villous tissues were collected to examine the expression of miR-150-5p and VEGFA by using quantitative polymerase chain rea…
View article: Application of a new multi-element integrated teaching mode based on bite-sized teaching, flipped classroom, and MOOC in clinical teaching of obstetrics and gynaecology
Application of a new multi-element integrated teaching mode based on bite-sized teaching, flipped classroom, and MOOC in clinical teaching of obstetrics and gynaecology Open
Context Effective clinical medical student education includes attention to teaching approaches. This study assessed the impact of a new multi-element teaching mode that utilizes Bite-Sized Teaching, flipped classroom, and MOOC on learner p…
View article: A novel clinical prediction model of severity based on red cell distribution width, neutrophil-lymphocyte ratio and intra-abdominal pressure in acute pancreatitis in pregnancy
A novel clinical prediction model of severity based on red cell distribution width, neutrophil-lymphocyte ratio and intra-abdominal pressure in acute pancreatitis in pregnancy Open
View article: Additional file 1 of Application of a new multi-element integrated teaching mode based on bite-sized teaching, flipped classroom, and MOOC in clinical teaching of obstetrics and gynaecology
Additional file 1 of Application of a new multi-element integrated teaching mode based on bite-sized teaching, flipped classroom, and MOOC in clinical teaching of obstetrics and gynaecology Open
Supplementary Material 1
View article: Accurate prediction of microvascular invasion occurrence and effective prognostic estimation for patients with hepatocellular carcinoma after radical surgical treatment
Accurate prediction of microvascular invasion occurrence and effective prognostic estimation for patients with hepatocellular carcinoma after radical surgical treatment Open
View article: Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma
Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma Open
This study presented a multifunctional CXCR4-targeted nanoparticle to conduct effective and mini-invasive phototherapeutics of orthotopic SHCCs via the real-time quantitative guidance by optical imaging, which provided a new perception for…
View article: Accurate prediction of microvascular invasion occurrence and effective prognostic estimation for patients with hepatocellular carcinoma after radical surgical treatment
Accurate prediction of microvascular invasion occurrence and effective prognostic estimation for patients with hepatocellular carcinoma after radical surgical treatment Open
Background Hepatocellular carcinoma (HCC) is the third most common cause of cancer death worldwide with an overall 5-year survival rate was less than 18%, which may be related to the tumor microvascular invasion (MVI). This study aims to c…
View article: Astragaloside-IV Inhibits Pancreatic Cancer Cell Proliferation in Vitro and in Vivo by Inducing Cell Cycle Arrest and Apoptosis
Astragaloside-IV Inhibits Pancreatic Cancer Cell Proliferation in Vitro and in Vivo by Inducing Cell Cycle Arrest and Apoptosis Open
Astragaloside IV (AS-IV) or 3-O-β-D-xylopyranosyl-6-O-β-D-glucopyranosylcyl-cloastragenol is a bioactive saponin extract from the root of Astragalus membranaceus. It has been proven to have an anti-tumor effect in a variety of tumors by in…
View article: Hsa_circ_0107593 Suppresses the Progression of Cervical Cancer via Sponging hsa-miR-20a-5p/93-5p/106b-5p
Hsa_circ_0107593 Suppresses the Progression of Cervical Cancer via Sponging hsa-miR-20a-5p/93-5p/106b-5p Open
Circular RNAs (circRNAs) are a new class of single-stranded RNAs that form a continuous loop with crucial role in regulation of gene expression. Because their circular conformation conforms numerous properties, circRNAs have been investiga…
View article: β‐catenin regulates IRF3‐mediated innate immune signalling in colorectal cancer
β‐catenin regulates IRF3‐mediated innate immune signalling in colorectal cancer Open
Objective β‐catenin is one of the most critical oncogenes associated with many kinds of human cancers, especially in the human CRC. Innate immunity recognizes tumour derived damage‐associated molecular patterns (DAMPs) and primes the anti‐…
View article: RETRACTED: Lnc<scp>RNA NR</scp>2F1‐<scp>AS</scp>1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting <scp>ABCC</scp>1 via miR‐363
RETRACTED: Lnc<span>RNA NR</span>2F1‐<span>AS</span>1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting <span>ABCC</span>1 via miR‐363 Open
Emerging evidence has validated the vital role of long non‐coding RNA (lnc RNA ) in the chemoresistance of cancer treatment. In the present study, we investigate the function of lnc RNA NR 2F1‐ AS 1 on oxaliplatin ( OXA ) resistance of hep…
View article: Hyper activation of β‐catenin signalling induced by <scp>IKK</scp>ε inhibition thwarts colorectal cancer cell proliferation
Hyper activation of β‐catenin signalling induced by <span>IKK</span>ε inhibition thwarts colorectal cancer cell proliferation Open
Objective Aberrant activation of Wnt/β‐catenin signalling contributes significantly to the development of human colorectal cancers and β‐catenin is the key signalling molecule transducing canonical Wnt/β‐catenin signalling. Therefore, β‐ca…