Chengmou Huang
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View article: Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation
Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation Open
These findings suggest a potential regulatory mechanism involving FUNDC2P4 and HSF1 that may contribute to HCC recurrence and metastasis after IRFA, warranting further in vivo and clinical investigation.
View article: Bevacizumab promotes active biological behaviors of human umbilical vein endothelial cells by activating TGFβ1 pathways <i>via</i> off-VEGF signaling
Bevacizumab promotes active biological behaviors of human umbilical vein endothelial cells by activating TGFβ1 pathways <i>via</i> off-VEGF signaling Open
Objective: Bevacizumab is a recombinant humanized monoclonal antibody that blocks vascular endothelial growth factor (VEGF) with clear clinical benefits. However, overall survival of some cancer types remains low owing to resistance to bev…