Chunhua Wan
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View article: Research on the Current Situation and Influencing Factors of Autonomous Learning Ability of Vocational Nursing Students
Research on the Current Situation and Influencing Factors of Autonomous Learning Ability of Vocational Nursing Students Open
Objective To investigate the current situation of self-learning ability of vocational nursing students in Shanghai and analyze its influencing factors. Method From October 2022 to December 2022, a random sampling method was used to select …
View article: Dynamic Response Simulation for a Novel Single-Point Mooring Gravity-Type Deep-Water Net Cage Under Irregular Wave and Current
Dynamic Response Simulation for a Novel Single-Point Mooring Gravity-Type Deep-Water Net Cage Under Irregular Wave and Current Open
This study investigated the structural response characteristics of a novel single-point mooring gravity-type deep-water (SPM-GDW) net cage under irregular waves and currents. A hydrodynamic numerical model of the cage was created and valid…
View article: Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development
Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development Open
Besides the canonical function in ribosome biogenesis, there have been significant recent advances towards the fascinating roles of the nucleolus in stress response, cell destiny decision and disease progression. Nucleolar stress, an emerg…
View article: Emerging Roles of the Nervous System in Gastrointestinal Cancer Development
Emerging Roles of the Nervous System in Gastrointestinal Cancer Development Open
Our understanding of the fascinating connection between nervous system and gastrointestinal (GI) tumorigenesis has expanded greatly in recent years. Recent studies revealed that neurogenesis plays an active part in GI tumor initiation and …
View article: MiR-539-5p alleviates sepsis-induced acute lung injury by targeting ROCK1
MiR-539-5p alleviates sepsis-induced acute lung injury by targeting ROCK1 Open
In conclusion, miR-539-5p alleviated sepsis-induced ALI via suppressing its downstream target ROCK1, suggesting a therapeutic potential of miR-539-5p for the management of sepsis-induced ALI.
View article: CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer
CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer Open
Chromobox protein homolog 7 (CBX7), one of the polycomb group (PcG) proteins, is a transcriptional repressor involved in the regulation of cell proliferation and senescence. In the present study, we showed that CBX7 negatively regulates th…
View article: The Role of PTP1B O-GlcNAcylation in Hepatic Insulin Resistance
The Role of PTP1B O-GlcNAcylation in Hepatic Insulin Resistance Open
Protein tyrosine phosphatase 1B (PTP1B), which can directly dephosphorylate both the insulin receptor and insulin receptor substrate 1 (IRS-1), thereby terminating insulin signaling, reportedly plays an important role in insulin resistance…
View article: Zinc deficiency impairs the renewal of hippocampal neural stem cells in adult rats: involvement of FoxO3a activation and downstream p27<sup>kip1</sup> expression
Zinc deficiency impairs the renewal of hippocampal neural stem cells in adult rats: involvement of FoxO3a activation and downstream p27<sup>kip1</sup> expression Open
Zinc plays an important role in the development and maintenance of central neural system. Zinc deficiency has been known to alter normal brain function, whose molecular mechanism remains largely elusive. In the present study, we establishe…