Chengzhang Wang
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View article: Selective Separation and Purification of Ginkgo Flavonol Glycosides Using Rutin Molecularly Imprinted Polymer
Selective Separation and Purification of Ginkgo Flavonol Glycosides Using Rutin Molecularly Imprinted Polymer Open
Ginkgo flavonol glycosides are widely used in the fields of food and medicine due to their free radical scavenging functions. The key to separating and purifying Ginkgo flavonol glycosides from complex Ginkgo biloba extracts is the selecti…
View article: Metabolomics and Antioxidant Activity of Valonea from Quercus variabilis Produced in Different Geographical Regions in China
Metabolomics and Antioxidant Activity of Valonea from Quercus variabilis Produced in Different Geographical Regions in China Open
The genus Quercus is widely distributed globally and serves as a potential source of phenolic compounds, which are renowned for their potent biological activities. The primary objective of this study was to determine the concentrations of …
View article: Development of a Cationic Photodynamic Antibacterial Agent Based on Gallic Acid and Ethylene Glycol Diglycidyl Ether and Enriched with Hydroxyl Groups for Effective Antimicrobial Therapy
Development of a Cationic Photodynamic Antibacterial Agent Based on Gallic Acid and Ethylene Glycol Diglycidyl Ether and Enriched with Hydroxyl Groups for Effective Antimicrobial Therapy Open
View article: Physicochemical properties and antibacterial activity evaluation of new indigo extract from Baphicacanthus cusia (Nees) Bremek prepared by chemical conversion method
Physicochemical properties and antibacterial activity evaluation of new indigo extract from Baphicacanthus cusia (Nees) Bremek prepared by chemical conversion method Open
The effect of acidolysis time, hydrochloric acid concentration, ozonization time and pH on the yield of indigo were investigated by single factor experiment using dried leaves of Baphicacanthus cusia (Nees) Bremek (DLB) as raw material. On…
View article: Synthesis of novel ursolic acid-gallate hybrids via 1,2,3-triazole linkage and its anti-oxidant and anti-inflammatory activity study
Synthesis of novel ursolic acid-gallate hybrids via 1,2,3-triazole linkage and its anti-oxidant and anti-inflammatory activity study Open
Excessive oxidation can lead to inflammation and affect health. Studies have shown that ursolic acid (UA) and gallic acid are widely employed in medicine and cosmetics owing to their obvious antioxidant and anti-inflammatory properties. In…
View article: Preparation of chlorophyll compounds and simulation of DFT optical properties assisted screening of photosensitizers from Ginkgo biloba leaves
Preparation of chlorophyll compounds and simulation of DFT optical properties assisted screening of photosensitizers from Ginkgo biloba leaves Open
Chlorophyll compounds (Chls) from Ginkgo biloba leaves (GBL) are non-toxic natural pigments characterized by highly conjugated molecules and special spectra, making them ideally potential photosensitizers (PSs) in photodynamics therapy (PD…
View article: Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy
Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy Open
Liposomes are considered the best nanocarrier for delivering cancer drugs such as chlorin e6 (Ce6) and paclitaxel (PTX). However, the poor stability and non-selectivity release of liposomes may severely limit their further applications. In…
View article: Synthesis of ursane-derived isothiocyanates and study of their reactions with series of amines and ammonia
Synthesis of ursane-derived isothiocyanates and study of their reactions with series of amines and ammonia Open
Based on ursolic acid, 3 compounds with isothiocyanate groups located at different distances from C-17 of the triterpenoid core have been synthesized through ursane-derived primary amines. To obtain terpene hybrids with thioureas and N,S-c…
View article: Preparation of polyprenol/poly (β-amino ester)/galactose targeted micelle carrier for enhancing cancer therapy
Preparation of polyprenol/poly (β-amino ester)/galactose targeted micelle carrier for enhancing cancer therapy Open
Lacking of substantial physiological activity and low utilization remains a problem for most conventional drug carriers. Polyprenol with beneficial medical effects and high availability could be an ideal candidate for solving this issue. H…
View article: Design and Synthesis of Novel Urushiol Derivatives as Potent Histone Deacetylase Inhibitors and Evaluation of Their Biological Properties
Design and Synthesis of Novel Urushiol Derivatives as Potent Histone Deacetylase Inhibitors and Evaluation of Their Biological Properties Open
View article: Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China)
Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China) Open
Physical parameters (i.e., extraction yield, oil content), chemicals (i.e., fatty acids, phenolics) and oxidative stability associated with virgin olive oil (VOO) from ten varieties in Wudu, China, were analyzed as a function of maturity i…
View article: Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation
Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation Open
There are numerous evaluations of natural products, of which majority are food bioactives, performed up to date for their various health beneficial activities via targeting specific proteins. However, the direct identification of a targete…
View article: Synthesis of water-soluble ester-linked ursolic acid–gallic acid hybrids with various hydrolytic stabilities
Synthesis of water-soluble ester-linked ursolic acid–gallic acid hybrids with various hydrolytic stabilities Open
To obtain derivatives of ursolic acid with improved water solubility and antioxidant activity, new ester-linked hybrids of ursolic acid and gallic acid were synthesized. In the reaction of methyl gallate with ursoloyl chloride acetate, bot…
View article: <p>Novel pH-Sensitive Urushiol-Loaded Polymeric Micelles for Enhanced Anticancer Activity</p>
Novel pH-Sensitive Urushiol-Loaded Polymeric Micelles for Enhanced Anticancer Activity Open
The pH-responsive urushiol-loaded micelles described in this study may be ideally suited for clinical use for the treatment of breast cancer.
View article: <p>Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells</p>
Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells Open
The NPs exhibited clear distribution characteristics, improved solubility and stability. BA and C60(OH)n for the NPs displayed a biphasic release pattern with sustained drug release properties. The mixture of C60…
View article: Preparation of water-in-oil microemulsion-based lacquer wax isopropyl ester and its UVA and UVB protection characteristics
Preparation of water-in-oil microemulsion-based lacquer wax isopropyl ester and its UVA and UVB protection characteristics Open
Lacquer wax represents a significant resource derived from the berries of Toxicodendron vernicifluum in China. The main chemical component of lacquer wax is fatty acid. The fatty acid isopropyl ester prepared from this acid has played a ro…
View article: Novel C15 Triene Triazole, D-A Derivatives Anti-HepG2, and as HDAC2 Inhibitors: A Synergy Study
Novel C15 Triene Triazole, D-A Derivatives Anti-HepG2, and as HDAC2 Inhibitors: A Synergy Study Open
A series of novel C15 urushiol derivatives were designed by introducing a pechmann structure and F-, Cl-, and Br-nitro substituents with different electronic properties into its alkyl side chain, as well as a triazolyl functional group in …
View article: Synthesis and Evaluation of C15 Triene Urushiol Derivatives as Potential Anticancer Agents and HDAC2 Inhibitor
Synthesis and Evaluation of C15 Triene Urushiol Derivatives as Potential Anticancer Agents and HDAC2 Inhibitor Open
A series of C15 triene urushiol derivatives were synthesized and evaluated for their anti-HepG2 aggregation in vitro. The results indicated that all compounds had an effective anti-HepG2 vitality. Compound 1 was a potent inhibitor of HepG2…
View article: Synergies of urushiol and its pechmann derivative compatible with paclitaxel anti-HepG2 activity
Synergies of urushiol and its pechmann derivative compatible with paclitaxel anti-HepG2 activity Open
The paper investigated the synergistic inhibitory effects of 1 (triene urushiol), 2 (monoene urushiol), 3 (urushiol pechmann derivative) and paclitaxel on proliferation of human hepatocellular carcinoma cell line HepG2…
View article: Thermal decomposition kinetics of raw and treated olive waste
Thermal decomposition kinetics of raw and treated olive waste Open
The pyrolysis characteristic of raw and ultrasound assisted enzyme hydrolysis treated (UAEH) olive waste was investigated using the thermogravimetric analysis at 5, 10, 15, and 20?C per minute in the nitrogen atmosphere. The thermal decomp…
View article: Boosting Learning Algorithm for Stock Price Forecasting
Boosting Learning Algorithm for Stock Price Forecasting Open
To tackle complexity and uncertainty of stock market behavior, more studies have introduced machine learning algorithms to forecast stock price. ANN (artificial neural network) is one of the most successful and promising applications. We p…
View article: Preparation of Starch-Hard Carbon Spherules from Ginkgo Seeds and Their Phenol-Adsorption Characteristics
Preparation of Starch-Hard Carbon Spherules from Ginkgo Seeds and Their Phenol-Adsorption Characteristics Open
Carbon spherules from ginkgo seed starch were prepared through stabilization and carbonization processes. The ginkgo seed starch was first stabilized at 195 °C for 18 h, then carbonized at 500 °C for 2 h under an N2 atmosphere. The charact…
View article: Optimization Technology of the LHS-1 Strain for Degrading Gallnut Water Extract and Appraisal of Benzene Ring Derivatives from Fermented Gallnut Water Extract Pyrolysis by Py-GC/MS
Optimization Technology of the LHS-1 Strain for Degrading Gallnut Water Extract and Appraisal of Benzene Ring Derivatives from Fermented Gallnut Water Extract Pyrolysis by Py-GC/MS Open
Gallnut water extract (GWE) enriches 80~90% of gallnut tannic acid (TA). In order to study the biodegradation of GWE into gallic acid (GA), the LHS-1 strain, a variant of Aspergillus niger, was chosen to determine the optimal degradation p…
View article: Characterization of polysaccharides purified from Lacquer tree seed cakes and its antioxidant activity
Characterization of polysaccharides purified from Lacquer tree seed cakes and its antioxidant activity Open
Three polysaccharides, LTPS-1, LTPS-21 and LTPS-31 were isolated and purified from the seed cakes of lacquer tree using DEAE-52 cellulose and Sephadex G-200 column chromatography. The total sugar contents of LTPS-1, LTPS-21 and LTPS…
View article: Thermal stability and thermal decomposition kinetics of Ginkgo biloba leaves waste residue
Thermal stability and thermal decomposition kinetics of Ginkgo biloba leaves waste residue Open
Non-isothermal thermogravimetric (TG) analysis was used to investigate the thermal stability and kinetics of three types of Ginkgo biloba leaves. These three types of Ginkgo biloba leaves included: Ginkgo biloba leaves before enzymolysis a…
View article: AdaBoost Artificial Neural Network for Stock Market Predicting
AdaBoost Artificial Neural Network for Stock Market Predicting Open
In this work, we propose a new direction of stock index movement prediction algorithm, coined the Ada-ANN forecasting model, which exploits AdaBoost theory and ANN to fulfill the predicting task. ANNs are employed as the weak forecasting m…
View article: State Grid Corporation based on big data platform for Overstaffing a Understaffing online analysis and Staff Allocation a Forecasting Research and Practice
State Grid Corporation based on big data platform for Overstaffing a Understaffing online analysis and Staff Allocation a Forecasting Research and Practice Open
According to the principle of "uniform standard, uniform process, uniform platform, uniform configuration", abide by the State Grid Corporation SG-ERP technical architecture, the big data technology is applied to the area of State Grid cor…
View article: Antibacterial, cytotoxic and genotoxic activity of nitrogenated and haloid derivatives of C50–C60 and C70–C120 polyprenol homologs
Antibacterial, cytotoxic and genotoxic activity of nitrogenated and haloid derivatives of C50–C60 and C70–C120 polyprenol homologs Open
View article: Analysis on the Physicochemical Properties of Ginkgo biloba Leaves after Enzymolysis Based Ultrasound Extraction and Soxhlet Extraction
Analysis on the Physicochemical Properties of Ginkgo biloba Leaves after Enzymolysis Based Ultrasound Extraction and Soxhlet Extraction Open
In this study, high performance liquid chromatography (HPLC), ultraviolet (UV), thermagravimetric analyzer (TGA), pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS), and scanning electron microscope (SEM) were used as measurement te…
View article: Polyprenols of<i>Ginkgo biloba</i>Enhance Antibacterial Activity of Five Classes of Antibiotics
Polyprenols of<i>Ginkgo biloba</i>Enhance Antibacterial Activity of Five Classes of Antibiotics Open
Polyprenol (GBP) from Ginkgo biloba Leaves (GBL) is an important lipid with many bioactive effects. The effect of GBP on antibacterial properties of five antibiotics belonging to different classes was through analysis of inhibition halos, …