Chunli Fu
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View article: 5-hydroxymethylcytosines from circulating cell-free DNA as noninvasive prognostic markers for gastric cancer
5-hydroxymethylcytosines from circulating cell-free DNA as noninvasive prognostic markers for gastric cancer Open
Background Prognostic assessment plays a crucial role in guiding clinical management and treatment decisions for gastric cancer patients. The enrichment characteristics of 5-hydroxymethylcytosine (5hmC) in circulating cell-free DNA (cfDNA)…
View article: Psychiatric safety associated with hormone replacement therapy for menopausal symptoms: a real-world study of the FDA adverse event reporting system
Psychiatric safety associated with hormone replacement therapy for menopausal symptoms: a real-world study of the FDA adverse event reporting system Open
Background Menopause is a significant phase in a woman’s life and is characterized by the cessation of ovarian function and a decline in endogenous ovarian hormone levels. This hormonal transition is often accompanied by debilitating sympt…
View article: Protein phosphatase 1 regulatory subunit 15 A (PPP1R15A) promoted the progression of gastric cancer by activating cell autophagy under energy stress
Protein phosphatase 1 regulatory subunit 15 A (PPP1R15A) promoted the progression of gastric cancer by activating cell autophagy under energy stress Open
Background Glucose metabolism plays a critical role in tumor progression. When glucose intake is insufficient and the tumor’s growth rate exceeds its energy supply, tumor cells typically adapt and overcome the energy stress through compens…
View article: Four-way game analysis of transformation and upgrading of manufacturing enterprises relying on industrial internet platform under developers’ participation
Four-way game analysis of transformation and upgrading of manufacturing enterprises relying on industrial internet platform under developers’ participation Open
The construction of the industrial Internet platform is the key to the digital, networked and intelligent transformation and innovation of the manufacturing industry. At present, there are some limitations in the research on the mechanism …
View article: Research on the Impact of Green TechnologyInnovation in the Manufacturing Industry on theHigh-Quality Development of the ManufacturingIndustry Under “Dual Circulation”
Research on the Impact of Green TechnologyInnovation in the Manufacturing Industry on theHigh-Quality Development of the ManufacturingIndustry Under “Dual Circulation” Open
View article: The regulation of MFG‐E8 on the mitophagy in diabetic sarcopenia via the HSPA1L‐Parkin pathway and the effect of D‐pinitol
The regulation of MFG‐E8 on the mitophagy in diabetic sarcopenia via the HSPA1L‐Parkin pathway and the effect of D‐pinitol Open
Background Diabetic sarcopenia is a disease‐related skeletal muscle disorder that causes progressive symptoms. The complete understanding of its pathogenesis is yet to be unravelled, which makes it difficult to develop effective therapeuti…
View article: A novel predictor for the use of concurrent chemotherapy in early-stage cervical cancer with intermediate-risk factors
A novel predictor for the use of concurrent chemotherapy in early-stage cervical cancer with intermediate-risk factors Open
Pretreatment CONUT score may be a predictive factor for the use of concurrent chemotherapy in early-stage cervical cancer with intermediate-risk factors during postoperative radiotherapy, and it can be helpful to determine the adjuvant tre…
View article: TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea Open
Background Pulmonary fibrosis (PF) is a chronic and potentially fatal lung disease and disorder. Although the active ingredients of ginseng honeysuckle superfine powdered tea (GHSPT) have been proven to have anti-inflammatory and antioxida…
View article: Metabolomics analysis reveals serum biomarkers in patients with diabetic sarcopenia
Metabolomics analysis reveals serum biomarkers in patients with diabetic sarcopenia Open
Introduction Diabetic sarcopenia (DS) is characterized by muscle atrophy, slower nerve conduction, reduced maximum tension generated by skeletal muscle contraction, and slower contraction rate. Hence, DS can cause limb movement degeneratio…
View article: Additional file 3 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
Additional file 3 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea Open
Additional file 3. Pos-neg table.
View article: Additional file 1 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
Additional file 1 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea Open
Additional file 1. Protein identification table.
View article: Additional file 2 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
Additional file 2 of TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea Open
Additional file 2. Peptide identification table.
View article: PRELP promotes myocardial fibrosis and ventricular remodelling after acute myocardial infarction by the wnt/β–catenin signalling pathway
PRELP promotes myocardial fibrosis and ventricular remodelling after acute myocardial infarction by the wnt/β–catenin signalling pathway Open
Our results showed that PRELP, through the wnt/β-catenin signalling pathway, led to myocardial fibrosis and ventricular remodelling following AMI.
View article: Effect of wearing masks on postoperative radiotherapy in cervical cancer patients during the COVID-19 pandemic: a retrospective study on acute toxicity
Effect of wearing masks on postoperative radiotherapy in cervical cancer patients during the COVID-19 pandemic: a retrospective study on acute toxicity Open
Background: The COVID-19 pandemic has created great challenges and requirements for radiotherapy. Mask wearing is an effective physical intervention against disease transmission and has been part of daily prevention strategies. The aim of …
View article: Protective Effect of MFG-E8 on Necroptosis-Induced Intestinal Inflammation and Enteroendocrine Cell Function in Diabetes
Protective Effect of MFG-E8 on Necroptosis-Induced Intestinal Inflammation and Enteroendocrine Cell Function in Diabetes Open
Low-grade inflammation is one of the characteristics of metabolic disorders induced by diabetes mellitus. The present study explores the underlying mechanism of milk fat globule epidermal growth factor 8 (MFG-E8) on necroptosis-induced int…
View article: A Novel Risk Factor for Para-Aortic Lymph Node Recurrence After Definite Pelvic Radiotherapy in Stage IIIB Cervical Cancer
A Novel Risk Factor for Para-Aortic Lymph Node Recurrence After Definite Pelvic Radiotherapy in Stage IIIB Cervical Cancer Open
Background: Studies determining which patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIIB disease benefit from prophylactic extended-field irradiation (EFRT), which can reduce para-aortic lymph node (PALN)…
View article: First-Generation Inference Accelerator Deployment at Facebook
First-Generation Inference Accelerator Deployment at Facebook Open
In this paper, we provide a deep dive into the deployment of inference accelerators at Facebook. Many of our ML workloads have unique characteristics, such as sparse memory accesses, large model sizes, as well as high compute, memory and n…
View article: EnRank: An Ensemble Method to Detect Pulmonary Hypertension Biomarkers Based on Feature Selection and Machine Learning Models
EnRank: An Ensemble Method to Detect Pulmonary Hypertension Biomarkers Based on Feature Selection and Machine Learning Models Open
Pulmonary hypertension (PH) is a common disease that affects the normal functioning of the human pulmonary arteries. The peripheral blood mononuclear cells (PMBCs) served as an ideal source for a minimally invasive disease diagnosis. This …
View article: Pretreatment Squamous Cell Carcinoma Antigen (SCC-Ag) as a Predictive Factor for the Use of Consolidation Chemotherapy in Cervical Cancer Patients After Postoperative Extended-Field Concurrent Chemoradiotherapy
Pretreatment Squamous Cell Carcinoma Antigen (SCC-Ag) as a Predictive Factor for the Use of Consolidation Chemotherapy in Cervical Cancer Patients After Postoperative Extended-Field Concurrent Chemoradiotherapy Open
Objective: The goal of this study was to confirm the clinical value of pretreatment serum squamous cell carcinoma antigen (SCC-Ag) in the administration of consolidation chemotherapy in patients with cervical cancers undergoing postoperati…
View article: Comparative Study of Two Short-Form Versions of the Montreal Cognitive Assessment for Screening of Post-Stroke Cognitive Impairment in a Chinese Population
Comparative Study of Two Short-Form Versions of the Montreal Cognitive Assessment for Screening of Post-Stroke Cognitive Impairment in a Chinese Population Open
Jingjing Wei,1– 3,* Xianglan Jin,2,* Baoxin Chen,2 Xuemei Liu,4 Hong Zheng,4 Rongjuan Guo,2 Xiao Liang,3 Chen Fu,2,4 Yunling Zhang2,3 1Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Depart…
View article: Adjuvant pelvic intensity-modulated radiotherapy and concurrent docetaxel and cisplatin chemotherapy for postoperative cervical cancer with adverse risk factors: a retrospective report on toxicity and outcome in a single institution
Adjuvant pelvic intensity-modulated radiotherapy and concurrent docetaxel and cisplatin chemotherapy for postoperative cervical cancer with adverse risk factors: a retrospective report on toxicity and outcome in a single institution Open
Background : To retrospectively assess the toxicity of delivering postoperative intensity-modulated radiotherapy (IMRT) and concurrent cisplatin and docetaxel chemotherapy to patients with cervical cancer and adverse risk factors. Methods …
View article: Empirical Research on Impact of Competitive Intensity on Safety Investment in High-Dangerous Industries
Empirical Research on Impact of Competitive Intensity on Safety Investment in High-Dangerous Industries Open