Chenjie Gao
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View article: Association of psychosocial factors and biological pathways identified from rare-variant analysis with longitudinal trajectories of treatment response in major depressive disorder
Association of psychosocial factors and biological pathways identified from rare-variant analysis with longitudinal trajectories of treatment response in major depressive disorder Open
View article: Prediction of Early Antidepressant Efficacy in Patients with Major Depressive Disorder Based on Multidimensional Features of rs-fMRI and <i>P11</i> Gene DNA Methylation: Prédiction de l’efficacité précoce d’un antidépresseur chez des patients souffrant du trouble dépressif majeur d’après les caractéristiques multidimensionnelles de la méthylation de l’ADN du gène P11 et de la IRMf-rs
Prediction of Early Antidepressant Efficacy in Patients with Major Depressive Disorder Based on Multidimensional Features of rs-fMRI and <i>P11</i> Gene DNA Methylation: Prédiction de l’efficacité précoce d’un antidépresseur chez des patients souffrant du trouble dépressif majeur d’après les caractéristiques multidimensionnelles de la méthylation de l’ADN du gène P11 et de la IRMf-rs Open
Objective This study established a machine learning model based on the multidimensional data of resting-state functional activity of the brain and P11 gene DNA methylation to predict the early efficacy of antidepressant treatment in patien…
View article: Escitalopram-induced QTc prolongation and its relationship with KCNQ1, KCNE1, and KCNH2 gene polymorphisms
Escitalopram-induced QTc prolongation and its relationship with KCNQ1, KCNE1, and KCNH2 gene polymorphisms Open
Aims: We investigated the influence of KCNQ1, KCNE1, and KCNH2 gene polymorphisms along with clinical factors on escitalopram-induced QTc prolongation. Methods: A total of 713 patients prescribed escitalopram were identified and had at lea…
View article: A Predictive Model of Risk Factors for Conversion From Major Depressive Disorder to Bipolar Disorder Based on Clinical Characteristics and Circadian Rhythm Gene Polymorphisms
A Predictive Model of Risk Factors for Conversion From Major Depressive Disorder to Bipolar Disorder Based on Clinical Characteristics and Circadian Rhythm Gene Polymorphisms Open
Background Bipolar disorder (BD) is easy to be misdiagnosed as major depressive disorder (MDD), which may contribute to a delay in treatment and affect prognosis. Circadian rhythm dysfunction is significantly associated with conversion fro…
View article: Influence and interaction of resting state functional magnetic resonance and tryptophan hydroxylase-2 methylation on short-term antidepressant drug response
Influence and interaction of resting state functional magnetic resonance and tryptophan hydroxylase-2 methylation on short-term antidepressant drug response Open
View article: The impact of <scp>HTR1A</scp> and <scp>HTR1B</scp> methylation combined with stress/genotype on early antidepressant efficacy
The impact of <span>HTR1A</span> and <span>HTR1B</span> methylation combined with stress/genotype on early antidepressant efficacy Open
Aims Antidepressants are effective in the treatment of major depressive disorder (MDD), while many patients fail to respond to antidepressants. Both 5‐HT1A (HTR1A) and 5‐HT1B (HTR1B) receptors play an important role in antidepressant activ…