Chenjie Xie
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View article: A diagnostic model based on transcriptomic analysis reveals inflammation as a potential prognosis factor for hepatoblastoma with hepatocellular carcinoma features
A diagnostic model based on transcriptomic analysis reveals inflammation as a potential prognosis factor for hepatoblastoma with hepatocellular carcinoma features Open
View article: Neutrophil-induced pyroptosis promotes survival in patients with hepatoblastoma
Neutrophil-induced pyroptosis promotes survival in patients with hepatoblastoma Open
The novel NIP score for patients with HB shows high predictive value for survival. Moreover, we identified biological function, cellular communication, and growth trajectories of neutrophils in HB. Our findings broaden insights into the tr…
View article: A Comparative Transcriptome Analysis Unveils the Mechanisms of Response in Feather Degradation by Pseudomonas aeruginosa Gxun-7
A Comparative Transcriptome Analysis Unveils the Mechanisms of Response in Feather Degradation by Pseudomonas aeruginosa Gxun-7 Open
Microbial degradation of feathers offers potential for bioremediation, yet the microbial response mechanisms warrant additional investigation. In prior work, Pseudomonas aeruginosa Gxun-7, which demonstrated robust degradation of feathers …
View article: PIVKA-II combined with alpha-fetoprotein for the diagnostic value of hepatic tumors in children: a multicenter, prospective observational study
PIVKA-II combined with alpha-fetoprotein for the diagnostic value of hepatic tumors in children: a multicenter, prospective observational study Open
View article: PIVKA-II Combined with Alpha-Fetoprotein for the Diagnostic Value of Hepatic Tumors in Children: A Multicenter, Prospective Observational Study
PIVKA-II Combined with Alpha-Fetoprotein for the Diagnostic Value of Hepatic Tumors in Children: A Multicenter, Prospective Observational Study Open
Background: To investigate whether protein induced by vitamin K antagonist-II (PIVKA-II) combined with alpha-fetoprotein (AFP) can improve the diagnostic and differential diagnostic accuracy of childhood hepatic tumors. Methods: A multi-ce…
View article: Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics
Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics Open
View article: PIVKA-II Combined with Alpha-Fetoprotein for the Diagnostic Value of Hepatic Tumors in Children: A Multicenter, Prospective Observational Study
PIVKA-II Combined with Alpha-Fetoprotein for the Diagnostic Value of Hepatic Tumors in Children: A Multicenter, Prospective Observational Study Open
Background:We aimed to investigate whether the protein induced by the vitamin K antagonist-II (PIVKA-II) combined with alpha-fetoprotein (AFP) can improve the diagnostic and differential diagnostic accuracy of childhood hepatic tumors.Meth…
View article: An analysis of the diagnosis, clinical characteristics, treatment, and survival outcomes of 36 extracranial malignant rhabdoid tumor patients
An analysis of the diagnosis, clinical characteristics, treatment, and survival outcomes of 36 extracranial malignant rhabdoid tumor patients Open
Those eMRTs treated according to SCMC protocol turned out to have poor outcomes. Higher staging at diagnosis and reoccurrence in younger patients remain major threats to the prognosis.
View article: Inflammatory myofibroblastic tumor successfully treated with metformin: A case report and review of literature
Inflammatory myofibroblastic tumor successfully treated with metformin: A case report and review of literature Open
The tumor was observed to have completely disappeared after treatment with metformin. Our finding is of great significance to facilitate future clinical treatment with IMT.
View article: Melanotic neuroectodermal tumor of infancy successfully treated with metformin
Melanotic neuroectodermal tumor of infancy successfully treated with metformin Open
Rationale: Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor originated from neural crest cells with the potential for recurrence and metastasis. The peak age for the disease is during the first year after birth. The curren…
View article: Gorham-Stout disease successfully treated with sirolimus (rapamycin): a case report and review of the literature
Gorham-Stout disease successfully treated with sirolimus (rapamycin): a case report and review of the literature Open
View article: Propranolol for infantile hepatic hemangioendothelioma: Clinical evaluation of drug efficacy and safety using a single-center patient cohort
Propranolol for infantile hepatic hemangioendothelioma: Clinical evaluation of drug efficacy and safety using a single-center patient cohort Open
This study indicates that both propranolol and sirolimus were effective drugs for the treatment of children with IHHE at SCMC.
View article: Metabolomics study of the metabolic changes in hepatoblastoma cells in response to NTCP/SLC10A1 overexpression
Metabolomics study of the metabolic changes in hepatoblastoma cells in response to NTCP/SLC10A1 overexpression Open
NTCP (SLC10A1) has been well recognized as a basolateral (sinusoidal) Na+-bile acid co-transporter that mediates the hepatic uptake of bile acids. However, little is known about the effects of NTCP (SLC10A1) on hepatoblastoma (HB) and its …
View article: Effectiveness of sirolimus in the treatment of complex lymphatic malformations: Single center report of 56 cases
Effectiveness of sirolimus in the treatment of complex lymphatic malformations: Single center report of 56 cases Open
View article: Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in Neuroblastoma
Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in Neuroblastoma Open
Neuroblastoma (NB) is the most common pediatric extra-cranial solid tumor with heterogeneous characteristics, and the prognosis of patients with high-risk NB is usually poor. Discovery of novel biomarkers for early detection and investigat…
View article: The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK
The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK Open
The proto-oncogene MYC can trigger the unfolded protein response (UPR). The double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK), one of three primary branches of the UPR, is a key regulator of autophagy, p…