Chenjing Zhang
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View article: MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain
MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain Open
PIEZO channels are mechanical force sensors involved in various biological processes, including somatosensation. To date, only a few PIEZO-binding partners have been identified, including MyoD-family inhibitor proteins (MDFI and MDFIC). He…
View article: A temporal study on NF-κB-mediated autonomous inflammatory response in iPSC-CMs induced by microwave radiation
A temporal study on NF-κB-mediated autonomous inflammatory response in iPSC-CMs induced by microwave radiation Open
The study aims to explore the new mechanism of human induced pluripotent stem cell-derived myocardial cells (iPSC-CMs) damage caused by microwave exposure, focusing on the changes in inflammatory factors, and to clarify the association bet…
View article: Visible Periodic Piezoelectric Domains in Silk Fibroin for Neurite‐Orientated Extension
Visible Periodic Piezoelectric Domains in Silk Fibroin for Neurite‐Orientated Extension Open
The development of visible periodic piezoelectric domains is highly attractive but challenging to overcome the homogeneous distribution and lack of visualization of the electric field on traditional piezopolymers. This work reports an in s…
View article: [Retracted] Selenium‑binding protein 1 may decrease gastric cellular proliferation and migration
[Retracted] Selenium‑binding protein 1 may decrease gastric cellular proliferation and migration Open
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the flow cytometric plots shown in Fig. 9A on p. 1628, a pair of data panels showed a surprisingly high level of partially over…
View article: On‐chip dual‐mode all‐optical multifunctional logic unit based on multimode FWMs
On‐chip dual‐mode all‐optical multifunctional logic unit based on multimode FWMs Open
An on‐chip dual‐mode all‐optical multifunctional logic operation unit including four AND and two OR logic gates is proposed and experimentally demonstrated. It is realized using multiple intra‐mode four‐wave mixing (FWM) processes in a mul…
View article: Effect of Acute Brief Social Isolation on Visceral Pain
Effect of Acute Brief Social Isolation on Visceral Pain Open
Acute short-term social isolation enhances visceral pain sensitivity, which could be related to an increase in stress levels.
View article: Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression
Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression Open
Increased IEL density and PD-1/PD-L1 expression correlate with cytological dysplasia progression and specifically with the XRCC1 mutation status in CRC. Our findings support a stepwise dysplasia-carcinoma sequence of adenoma carcinogenesis…
View article: Risk of esophageal adenocarcinoma in patients with Barrett’s esophagus using proton pump inhibitors: a systematic review with meta-analysis and sequential trial analysis
Risk of esophageal adenocarcinoma in patients with Barrett’s esophagus using proton pump inhibitors: a systematic review with meta-analysis and sequential trial analysis Open
According to the Meta analysis and TSA of existing studies, the protective effect of PPIs on the progression of BE patients to EAC and/or HGD has not been confirmed. TSA shows that more patients are needed before a clear conclusion can be …
View article: The Sustained Antidepressant Effects of Ketamine Are Independent of the Lateral Habenula
The Sustained Antidepressant Effects of Ketamine Are Independent of the Lateral Habenula Open
Ketamine is known to have a rapid and lasting antidepressant effect. Recent studies have shown that ketamine exerts it rapid antidepressant effect by blocking burst firing in the lateral habenula (LHb). Whether the sustained antidepressant…
View article: A novel nomogram for predicting survival of patients with poorly differentiated gastric adenocarcinoma
A novel nomogram for predicting survival of patients with poorly differentiated gastric adenocarcinoma Open
The nomogram, established herein, was more accurate in predicting the 1-, 3-, and 5-year OS of PDGA patients than the traditional AJCC TNA staging system. Successful establishment of a PDGA prognostic nomogram is a further step towards ind…
View article: Circular RNA circCOL6A3_030 is involved in the metastasis of gastric cancer by encoding polypeptide
Circular RNA circCOL6A3_030 is involved in the metastasis of gastric cancer by encoding polypeptide Open
Gastric cancer (GC) is a serious digestive tract disease that threatens human life worldwide, and the prognosis of gastric cancer accompanied by distant lymph node or the distant metastasis organs is worse. The purpose of this study was to…
View article: Application of machine learning in the diagnosis of gastric cancer based on noninvasive characteristics
Application of machine learning in the diagnosis of gastric cancer based on noninvasive characteristics Open
Background The diagnosis of gastric cancer mainly relies on endoscopy, which is invasive and costly. The aim of this study is to develop a predictive model for the diagnosis of gastric cancer based on noninvasive characteristics. Aims To c…
View article: Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma
Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma Open
Background: Dysregulation of circular RNA (circRNA) expression is involved in the progression of cancer. Here, we aimed to study the potential function of hsa_circ_0006401 in colorectal cancer (CRC). Methods: CircRNA hsa_circ_0006401 expre…
View article: circCOL6A3_030 is involved in the metastasis of gastric cancer by encoding polypeptide
circCOL6A3_030 is involved in the metastasis of gastric cancer by encoding polypeptide Open
Background Gastric cancer (GC) is a serious digestive tract disease that threatens human life worldwide, and the prognosis of gastric cancer accompanied by distant lymph node or the distant metastasis organs is worse. The purpose of this s…
View article: Risk of Esophageal Adenocarcinoma in Patients With Barrett's Esophagus Using Proton Pump Inhibitors: A Systematic Review With Meta-Analysis and Trial Sequential Analysis
Risk of Esophageal Adenocarcinoma in Patients With Barrett's Esophagus Using Proton Pump Inhibitors: A Systematic Review With Meta-Analysis and Trial Sequential Analysis Open
Background: Proton pump inhibitors (PPIs) have been used to treat Barrett's esophagus (BE), but there seems to be insufficient evidence that PPIs can prevent esophageal adenocarcinoma (EAC) and high grade dysplasia (HGD). This study aimed …
View article: Systematic Review with Meta-analysis: Association of Helicobacter pylori Infection with Esophageal Cancer
Systematic Review with Meta-analysis: Association of Helicobacter pylori Infection with Esophageal Cancer Open
Background . Helicobacter pylori is an important carcinogenic factor in gastric cancer. Studies have shown that Helicobacter pylori infection is inversely associated with certain diseases such as esophageal cancer and whose infection appea…
View article: Green Extraction of Phenolic Acids from Artemisia argyi Leaves by Tailor-Made Ternary Deep Eutectic Solvents
Green Extraction of Phenolic Acids from Artemisia argyi Leaves by Tailor-Made Ternary Deep Eutectic Solvents Open
The Artemisia argyi leaf (AL) has been used as a traditional medicine and food supplement in China and other Asian countries for hundreds of years. Phytochemical studies disclosed that AL contains various bioactive constituents. Among bioa…
View article: Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo
Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo Open
BACKGROUND Usnic acid (UA), a secondary metabolite, is mainly derived from certain lichen species. Growing evidence suggests that UA has antitumor, anti-oxidative, anti-inflammatory, and other activities in a variety of cancer cells. Howev…
View article: TGFβ1 Promotes Breast Cancer Local Invasion and Liver Metastasis by Increasing the CD44<sup>high</sup>/CD24<sup>−</sup> Subpopulation
TGFβ1 Promotes Breast Cancer Local Invasion and Liver Metastasis by Increasing the CD44<sup>high</sup>/CD24<sup>−</sup> Subpopulation Open
Objective: Previous studies have shown that the transforming growth factor β1 pathway plays an important role in breast cancer metastasis to the liver. However, the mechanism of this metastasis has not been fully clarified. Cancer stem cel…