Chenshi Lin
YOU?
Author Swipe
View article: The emerging roles and mechanisms of FAM83H‑AS1 in cancer: Pathophysiology and therapeutic implications (Review)
The emerging roles and mechanisms of FAM83H‑AS1 in cancer: Pathophysiology and therapeutic implications (Review) Open
Long non-coding RNAs (lncRNAs) are key regulators of gene expression at transcriptional and post-transcriptional levels and serve roles in tumour progression, cancer diagnosis and prognosis. Among these, family with sequence similarity 83 …
View article: Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing
Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing Open
Wound healing is a highly orchestrated, multiphase process that involves various cell types and molecular pathways. Recent advances in single-cell transcriptomics and machine learning have provided unprecedented insights into the complexit…
View article: Bletilla Striata Polysaccharide Protects Against Uva-Induced Skin Damage by Activating Nrf2/Ho-1 Signaling and Inhibiting Ferroptosis
Bletilla Striata Polysaccharide Protects Against Uva-Induced Skin Damage by Activating Nrf2/Ho-1 Signaling and Inhibiting Ferroptosis Open
View article: Lysine-Specific Demethylase 1 (LSD1) Modulates Hypoxia and Antitumor Immunity Pathways in Triple Negative Breast Cancer
Lysine-Specific Demethylase 1 (LSD1) Modulates Hypoxia and Antitumor Immunity Pathways in Triple Negative Breast Cancer Open
Epigenetic alterations can disrupt gene functions and lead to cellular neoplastic transformation, significantly contributing to cancer initiation and progression, including triple-negative breast cancer (TNBC). Inhibitors of lysine-specifi…
View article: Efficacy and Safety of Primary Radiotherapy in Combination with EGFR-TKIs for Non-Small Cell Lung Cancer Harboring EGFR Mutation
Efficacy and Safety of Primary Radiotherapy in Combination with EGFR-TKIs for Non-Small Cell Lung Cancer Harboring EGFR Mutation Open
View article: The Therapeutic Potential of Metformin for Metabolic Associated Fatty Liver Disease: Bioinformatics Analysis
The Therapeutic Potential of Metformin for Metabolic Associated Fatty Liver Disease: Bioinformatics Analysis Open
Metabolic associated fatty liver disease (MAFLD) is associated with obesity and metabolic dysfunctions, but its molecular mechanisms remain elusive and effective treatments are lacking. Metformin is a potential therapeutic agent for MAFLD …
View article: A Case of Pseudohypoparathyroidism Misdiagnosed as Idiopathic Epilepsy for 5 Years: Clinical Analysis and Follow-up Outcomes
A Case of Pseudohypoparathyroidism Misdiagnosed as Idiopathic Epilepsy for 5 Years: Clinical Analysis and Follow-up Outcomes Open
We report a 15-year-old Chinese girl who presented with intermittent seizure episodes and had been misdiagnosed as having idiopathic epilepsy 5 years previously. Laboratory testing revealed hypocalcemia, hyperphosphatemia, and a high parat…
View article: Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis
Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis Open
Objective To compare the efficacy and safety between and within glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT-2is) in overweight or obese adults with or without diabetes mellitus. …
View article: Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries
Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries Open
View article: CKAP2 overexpression correlates with worse overall survival in patients with lung adenocarcinoma
CKAP2 overexpression correlates with worse overall survival in patients with lung adenocarcinoma Open
Background: Adenocarcinoma is a non–small-cell lung cancer that is common cancer in both genders, and has poor clinical outcomes. We aimed to evaluate the role of cytoskeleton-associated protein 2 (CKAP2), its prognostic significance, and …
View article: Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis
Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis Open
Objective To compare the efficacy and safety between and within glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose co-transporter 2 inhibitors (SGLT-2is) in overweight or obese adults with or without diabetes mellitus.…
View article: A rare case of 17α-hydroxylase/17, 20-lyase deficiency: Clinical and genetic findings and follow-up outcomes
A rare case of 17α-hydroxylase/17, 20-lyase deficiency: Clinical and genetic findings and follow-up outcomes Open
Here, we reported a case of a 16-year-old Chinese female patient (46, XX) diagnosed as 17α-hydroxylase/17, 20-lyase deficiency (17-OHD) in June 2018 and over 3 years follow-up outcomes; 17-OHD is a rare form of congenital adrenal hyperplas…
View article: Targeted delivery of baicalein-p53 complex to smooth muscle cells reverses pulmonary hypertension
Targeted delivery of baicalein-p53 complex to smooth muscle cells reverses pulmonary hypertension Open
View article: Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice
Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice Open
These data show that adipocyte ILK is important for regulating HF diet-mediated insulin resistance in AT in a manner consistent with AT function.
View article: Intracellular codelivery of anti-inflammatory drug and anti-miR 155 to treat inflammatory disease
Intracellular codelivery of anti-inflammatory drug and anti-miR 155 to treat inflammatory disease Open