Chenyang Huang
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View article: 918 Cytotoxic T cell expansion and tumor suppression through activation of CpG-ODN-induced neutrophils in mouse liver tumors
918 Cytotoxic T cell expansion and tumor suppression through activation of CpG-ODN-induced neutrophils in mouse liver tumors Open
View article: Distinct genomic subgroups and mutational patterns in undifferentiated/dedifferentiated endometrial carcinoma
Distinct genomic subgroups and mutational patterns in undifferentiated/dedifferentiated endometrial carcinoma Open
View article: It Takes Two: Your GRPO Is Secretly DPO
It Takes Two: Your GRPO Is Secretly DPO Open
Group Relative Policy Optimization (GRPO) is a prominent reinforcement learning algorithm for post-training Large Language Models (LLMs). It is commonly believed that GRPO necessitates a large group size to ensure stable training via preci…
View article: From individual carbon inequality to equitable provincial mitigation effort-sharing in China
From individual carbon inequality to equitable provincial mitigation effort-sharing in China Open
Provincial-level mitigation responsibilities in China typically focus on production-based targets, overlooking significant inequalities in individual carbon footprints (CFs). Here, we quantify individual consumption and investment CFs acro…
View article: Impact of Transfer Timing on Day-6 Blastocyst Pregnancy Outcomes in HRT Cycles of 2021–2024
Impact of Transfer Timing on Day-6 Blastocyst Pregnancy Outcomes in HRT Cycles of 2021–2024 Open
In conclusion, our retrospective data suggest that transferring single D6 blastocysts on either the sixth or seventh day of progesterone administration in HRT-FET cycles yields comparable clinical pregnancy outcomes. Until further prospect…
View article: Analysis of risk factors and early prediction model construction for gestational hypertension
Analysis of risk factors and early prediction model construction for gestational hypertension Open
Gestational hypertension (GH), a prevalent pregnancy complication, requires early risk identification for timely intervention. This study assesses and compares traditional and placental function factors using multivariable logistic regress…
View article: Magnetic field imaging based on weak measurement
Magnetic field imaging based on weak measurement Open
This study presents a weak measurement based magnetic field imaging method and system that utilizes the amplification mechanism of weak values on optical rotation and the magneto-optical effect to visualize magnetic field distributions. Ou…
View article: Impact of Elevated Oestrogen Levels on hCG Trigger Day on Clinical Pregnancy Outcome and OHSS Incidence in Long-Acting GnRHa Down-Regulated IVF/ICSI-ET Cycles
Impact of Elevated Oestrogen Levels on hCG Trigger Day on Clinical Pregnancy Outcome and OHSS Incidence in Long-Acting GnRHa Down-Regulated IVF/ICSI-ET Cycles Open
The CPR decreased significantly as E2 levels increased with serum E level higher than 5000 pg/mL on the hCG day, which was more obvious in blastocyst transfer than cleavage-stage embryo transfer. In addition, the incidence of mo…
View article: Optimizing primary tumor resection decisions for non-small cell lung cancer patients with brain metastases: analysis based on the SEER database and development and external validation of predictive models
Optimizing primary tumor resection decisions for non-small cell lung cancer patients with brain metastases: analysis based on the SEER database and development and external validation of predictive models Open
This study indicated that PTR can enhance the prognosis of NSCLC patients with BM and also establishes an effective screening tool for quantifying the likelihood of patient benefiting from PTR treatment.
View article: IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner
IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner Open
Primordial germ cells (PGCs) are specified early during embryogenesis and establish the germ cell lineage for transmitting genetic and epigenetic information from parents to offspring. However, whether N6-methyladenosine (m…
View article: Exploring Pea Soaking Water as Alternative to Synthetic Fertilizer: Growth and Microbial Analysis of Pea and Tomato Plants
Exploring Pea Soaking Water as Alternative to Synthetic Fertilizer: Growth and Microbial Analysis of Pea and Tomato Plants Open
This study investigated the viability of using pea soaking water (PSW) as substitute for synthetic fertilizers to enhance the growth of pea and tomato plants. Traits included plant growth stages, shoot and root weight, estimated chlorophyl…
View article: EBBS: An Ensemble with Bi-Level Beam Search for Zero-Shot Machine Translation
EBBS: An Ensemble with Bi-Level Beam Search for Zero-Shot Machine Translation Open
The ability of zero-shot translation emerges when we train a multilingual model with certain translation directions; the model can then directly translate in unseen directions. Alternatively, zero-shot translation can be accomplished by pi…
View article: Curculigoside is a Promising Osteoprotective Agent for Osteoporosis: Review
Curculigoside is a Promising Osteoprotective Agent for Osteoporosis: Review Open
The prevention and treatment of osteoporosis (OP) is one of the major issues in coping with the aging population; however, there are limited treatments available for OP. In-depth study of OP pathogenesis and development of new therapeutic …
View article: The impact of long-acting Gonadotropin-releasing hormone agonist pretreatment on the clinical pregnancy outcomes of hormone replacement therapy-frozen embryo transfer in recurrent implantation failure patients with and without polycystic ovary syndrome: a retrospective clinical study
The impact of long-acting Gonadotropin-releasing hormone agonist pretreatment on the clinical pregnancy outcomes of hormone replacement therapy-frozen embryo transfer in recurrent implantation failure patients with and without polycystic ovary syndrome: a retrospective clinical study Open
Our study demonstrates that long-acting GnRHa pretreatment can enhance clinical pregnancy outcomes in patients with RIF. Among RIF patients without PCOS, the clinical pregnancy rate exhibited a significant increase following GnRHa pretreat…
View article: A Decoding Algorithm for Length-Control Summarization Based on Directed Acyclic Transformers
A Decoding Algorithm for Length-Control Summarization Based on Directed Acyclic Transformers Open
Length-control summarization aims to condense long texts into a short one within a certain length limit. Previous approaches often use autoregressive (AR) models and treat the length requirement as a soft constraint, which may not always b…
View article: Induction of DNA Single Strand Breaks and Base Damages by Ultra-High Dose Rate Irradiation
Induction of DNA Single Strand Breaks and Base Damages by Ultra-High Dose Rate Irradiation Open
Background: The study of different types of DNA damage after ultra-high dose rate irradiation (UHDR) is of great significance for further understanding the mechanism of FLASH effect. Methods: pBR322 plasmid DNA was irradiated by electron F…
View article: Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy
Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy Open
In an effort to address the detrimental effects of myocardial ischemia/reperfusion injury (MI/RI), this study introduces a novel therapeutic strategy that involves a microneedle (MN) patch loaded with exosomes derived from human umbilical …
View article: Association between age at first birth and risk of rheumatoid arthritis in women: Evidence from NHANES 2011–2020
Association between age at first birth and risk of rheumatoid arthritis in women: Evidence from NHANES 2011–2020 Open
Objective This study focused on investigating the relation of age at first birth (AFB) with rheumatoid arthritis (RA) risk in women based on the 2011–2020 NHANES (National Health and Nutrition Examination Survey) data. Methods Women were a…
View article: Multivariable model for predicting 5-year survival in patients with EGFR-mutated non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors: a retrospective study
Multivariable model for predicting 5-year survival in patients with EGFR-mutated non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors: a retrospective study Open
Background: Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. In Asian populations, epidermal growth factor receptor (EGFR) mutations are particularly prevalent, leading to the development of EG…
View article: Real-World Efficacy and Safety of S-1 Monotherapy in Non-Small Cell Lung Cancer Management: Insights From a Multicenter Retrospective Cohort Study
Real-World Efficacy and Safety of S-1 Monotherapy in Non-Small Cell Lung Cancer Management: Insights From a Multicenter Retrospective Cohort Study Open
Background: S-1, an oral chemotherapy combining tegafur, gimeracil, and oteracil, has shown efficacy comparable with docetaxel for advanced non-small cell lung cancer (NSCLC) in clinical trials. However, its real-world effectiveness and sa…
View article: Magnetically Actuated Soft Electrodes for Multisite Bioelectrical Monitoring of Ex Vivo Tissues
Magnetically Actuated Soft Electrodes for Multisite Bioelectrical Monitoring of Ex Vivo Tissues Open
Multisite electrophysiological monitoring of ex vivo tissues and organ models is essential for basic research and drug toxicity evaluation. However, conventional microelectrode arrays with fixed positions and rigid structures are insuffici…
View article: Environmental-Driven Degration of Violet Phosphorus and its Passivation by Graphene
Environmental-Driven Degration of Violet Phosphorus and its Passivation by Graphene Open
View article: The Molecular Mechanism of Mycelial Incubation Time Effects on Primordium Formation of Pleurotus tuoliensis Through Transcriptome and Lipidomic Analyses
The Molecular Mechanism of Mycelial Incubation Time Effects on Primordium Formation of Pleurotus tuoliensis Through Transcriptome and Lipidomic Analyses Open
Pleurotus tuoliensis is a precious edible mushroom with a long cultivation cycle. Despite being cultivated in China for nearly 30 years, research on the molecular mechanisms underlying its primordium formation remains limited. In this stud…
View article: Surgical intervention for cauda equina syndrome without imaging features：A case report
Surgical intervention for cauda equina syndrome without imaging features：A case report Open
View article: The Cumulation of Debris Clouds around a Fast-rotating Asteroid
The Cumulation of Debris Clouds around a Fast-rotating Asteroid Open
The rotational mass loss has been realized to be a prevalent mechanism to produce low-speed debris near the asteroid, and the size composition of the asteroid’s surface regolith has been closely measured by in situ explorations. However, t…
View article: The impact of long-acting GnRHa pretreatment on the clinical pregnancy outcomes of hormone replacement therapy-frozen embryo transfer in RIF patients with PCOS: a retrospective clinical study
The impact of long-acting GnRHa pretreatment on the clinical pregnancy outcomes of hormone replacement therapy-frozen embryo transfer in RIF patients with PCOS: a retrospective clinical study Open
Background Several studies have demonstrated that pre-treatment with long-acting Gonadotropin-Releasing Hormone agonists (GnRHa) can significantly enhance the clinical pregnancy rate among recurrent implantation failure (RIF) patients. Inv…
View article: Comparative study on the association between types of physical activity, physical activity levels, and the incidence of osteoarthritis in adults: the NHANES 2007–2020
Comparative study on the association between types of physical activity, physical activity levels, and the incidence of osteoarthritis in adults: the NHANES 2007–2020 Open
It is known that physical activity is beneficial for the prevention of osteoarthritis (OA), but specific discussions on which types and levels of physical activity are more effective in reducing the incidence of OA are restricted. This stu…
View article: Comparative Study on the Association Between Types of Physical Activity, Physical Activity Levels, and the Incidence of Osteoarthritis in Adults：The NHANES 2007–2020
Comparative Study on the Association Between Types of Physical Activity, Physical Activity Levels, and the Incidence of Osteoarthritis in Adults：The NHANES 2007–2020 Open
Background: It is known that physical activity is beneficial to the prevention of osteoarthritis, but specific discussions on which types and levels of physical activity are more effective in reducing the incidence of osteoarthritis are re…
View article: Molecular mechanism of delayed development by interfering RNA targeting the phenylalanine ammonia lyase gene (pal1) in Pleurotus ostreatus
Molecular mechanism of delayed development by interfering RNA targeting the phenylalanine ammonia lyase gene (pal1) in Pleurotus ostreatus Open
The blockage of the development of edible mushrooms will affect the production cycle and yield of fruiting bodies. Phenylalanine ammonia lyase (PAL, EC 4.3.1.5) is an enzyme that catalyses the deamination of phenylalanine to form trans-cin…
View article: OTTAWA: Optimal TransporT Adaptive Word Aligner for Hallucination and Omission Translation Errors Detection
OTTAWA: Optimal TransporT Adaptive Word Aligner for Hallucination and Omission Translation Errors Detection Open
Recently, there has been considerable attention on detecting hallucinations and omissions in Machine Translation (MT) systems. The two dominant approaches to tackle this task involve analyzing the MT system's internal states or relying on …