Chenyi Sheng
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View article: ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network
ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network Open
Drug resistance in breast cancer (BC) is a clinical challenge. Exploring the mechanism and identifying a precise predictive biomarker for the drug resistance in BC is critical. Three first-line drug (paclitaxel, doxorubicin and tamoxifen) …
View article: A Novel Ferroptosis-Related Gene Signature for Chemotherapy Resistance Prediction in Triple-negative Breast Cancer
A Novel Ferroptosis-Related Gene Signature for Chemotherapy Resistance Prediction in Triple-negative Breast Cancer Open
Taxanes are first-line chemotherapeutic agents for patients with triple-negative breast cancer (TNBC). However, resistance, the main cause of clinical treatment failure and poor prognosis, reduces their effectiveness and has become an incr…
View article: A Preliminary Study of Ultrasound-Guided Microwave Ablation for Nonpuerperal Mastitis Treatment
A Preliminary Study of Ultrasound-Guided Microwave Ablation for Nonpuerperal Mastitis Treatment Open
Introduction: This study investigated the feasibility of ultrasound (US)-guided microwave ablation (MWA) as a treatment for nonpuerperal mastitis (NPM). Methods: Fifty-three patients with NPM diagnosed by biopsy and treated with US-guided …
View article: Knockdown of Ran GTPase expression inhibits the proliferation and migration of breast cancer cells
Knockdown of Ran GTPase expression inhibits the proliferation and migration of breast cancer cells Open
Breast cancer is the second leading cause of cancer-associated mortality in women worldwide. Strong evidence has suggested that Ran, which is a small GTP binding protein involved in the transport of RNA and protein across the nucleus, may …
View article: Suppression of Kpnβ1 expression inhibits human breast cancer cell proliferation by abrogating nuclear transport of Her2
Suppression of Kpnβ1 expression inhibits human breast cancer cell proliferation by abrogating nuclear transport of Her2 Open
Breast cancer (BC) is one of the most fatal diseases and poses critical health problems worldwide. However, its mechanisms remain unclear. Consequently, there is an urgency to investigate the mechanisms involved in BC initiation and progre…