Explanipedia

Smart injectable hydrogels for periodontal regeneration: Recent advancements in biomaterials and biofabrication strategies Open

Bohan Yin, Jagan Mohan Dodda, Siu Hong Dexter Wong, G. Roshan Deen, Jeffrey S Bate , et al. · 2025

Relationship of Fracture Morphological Characteristics with Posterolateral Corner Injuries in Hyperextension Varus Tibial Plateau Fractures Open

Binghao Wang, Teng Ye, Bin-bin Zhang, Yukai Wang, Yi Zhu , et al. · 2024

Background: Hyperextension varus tibial plateau fracture (HVTPF) is known to present with concomitant injuries to the posterolateral corner (PLC). However, the exact rate and characteristics of these injuries remain unclear. The primary ob…

Biomechanical evaluation of different medial column fixation patterns for valgus pilon fractures Open

Binghao Wang, Bin-Bin Zhang, Zi-Ling Gong, Jiong Mei, Congfeng Luo , et al. · 2024

Background The purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon fractures in a case-based model. Methods Based on the fracture mapping, 48 valgus pilon frac…

Incidence and Characteristics of Knee Ligament and Meniscal Injuries in Patients With Posterolateral Tibial Plateau Fractures Open

Binghao Wang, Yi Zhu, Binbin Zhang, Yukai Wang, Lifeng Yan , et al. · 2024

Background: Anterior cruciate ligament (ACL) tears are commonly seen with concomitant injuries to the posterolateral tibial plateau, while the occurrence of ACL injuries in posterolateral tibial plateau fractures (PTPFs) remains unclear. P…

Effectiveness of blood flow restriction versus traditional weight-bearing training in rehabilitation of knee osteoarthritis patients with MASLD: a multicenter randomized controlled trial Open

Chengfang Hu, Bin Zhu, Yanmao Wang, Fei Yang, Jun Zhang , et al. · 2023

To compare the reliability and effectiveness of blood blow restriction resistance training (BFR) versus traditional weight-bearing training (WB) in knee osteoarthritis (KOA) patients with metabolic dysfunction-associated steatotic liver di…

Biomechanical study of a new rim plate fixation strategy for two kinds of posterolateral depression patterns of tibial plateau fractures: a finite element analysis Open

Binbin Zhang, B.-L. Wang, Jiong Mei, Congfeng Luo, Yi Zhu · 2023

Purpose The biomechanical capacity of “Barrel Hoop Plate (BHP)” in the treatment of the posterolateral tibial plateau (PL) depression fractures remains unknown. In this study, two kinds of posterolateral tibial plateau depression models in…

Combined Proximal Tibial Osteotomy for Adult Kashin–Beck Disease with Severe Varus Knee Osteoarthritis: Case Report and Literature Review Open

Yunfei Liu, Ruiyang Li, Yu Zhan, Xuetao Xie, Congfeng Luo · 2022

Background Kashin–Beck disease (KBD) is an endemic, chronic osteoarthropathy that seriously affects joint function and can lead to severe knee deformity. Osteotomy is considered to be one of the effective methods for the treatment of this …

Ability of modern proximal tibial lateral plates to capture posterolateral tibial plateau fracture fragments Open

Lifeng Yan, Yu Zhan, Xuetao Xie, Yukai Wang, Yingqi Zhang , et al. · 2022

The proposed new digital methodology was demonstrated feasible and may improve the quantitative evaluation of the implants and optimize the design of implants. The commercially available proximal tibial lateral plate-screw constructs were …

Efficacy of leg swing versus quadriceps strengthening exercise among patients with knee osteoarthritis: study protocol for a randomized controlled trial Open

Ruiyang Li, Pingping Sun, Yu Zhan, Xuetao Xie, Weibing Yan , et al. · 2022

Three-dimensional computed tomography mapping and analysis of distal femur fractures (AO/OTA types 33A, 33B, and 33C) Open

Ruiyang Li, Yingjie Zhuge, Yu Zhan, Xuetao Xie, Congfeng Luo · 2022

The intercondylar fracture patterns in AO/OTA type B and type C fractures were similar, while the supracondylar characteristics in AO/OTA type A and type C were different. The findings in this study can help orthopaedic surgeons better und…

[Research progress of osteotomy around knee in the treatment of valgus knee osteoarthritis]. Open

Yunfei Liu, Xuetao Xie, Congfeng Luo · 2022

There are many osteotomies in the treatment of valgus knee osteoarthritis. In order to achieve good results, improve survival rate, and reduce postoperative complications, the most reasonable surgical strategy needs to be developed accordi…

Efficacy of Leg Swing Versus Quadriceps Strengthening Exercise Among Patients With Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial Open

Ruiyang Li, Pingping Sun, Yu Zhan, Xuetao Xie, Weibing Yan , et al. · 2021

Background Knee osteoarthritis (OA) is a leading cause of global disability. According to guidelines, thus far, exercise is the most recommended and important non-surgical treatment for knee OA. However, the best type of exercise for this …

Three-dimensional fracture mapping of multi-fragmentary patella fractures (AO/OTA 34C3) Open

Yu Zhan, Yingqi Zhang, Xuetao Xie, Congfeng Luo · 2021

Supero-medial corner of the patella was seldomly involved, and might be used as the cornerstone for fixation. Coronal fragments were common on both anterior and posterior patella surfaces, justifying the application of anterior plate osteo…

MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling Open

Wei Zhang, Chengfang Hu, Chi Zhang, Congfeng Luo, Biao Zhong , et al. · 2021

Background Osteoarthritis (OA) is a commonly known prevalent joint disease, with limited therapeutic methods. This study aimed to investigate the functions of miRNA-132 (miR-132) in the modulation of PTEN/PI3K/AKT signaling pathway in the …

Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression Open

Wei Zhang, Chi Zhang, Chengfang Hu, Congfeng Luo, Biao Zhong , et al. · 2020

Evaluation of an expectation and outcome measurement questionnaire in ankle fracture patients: The Trauma Expectation Factor Trauma Outcomes Measure (TEFTOM) Eurasia study Open

Christian Fang, Andreas Platz, Lars Peter Müller, Thomas Chandy, Congfeng Luo , et al. · 2020

Background: The Trauma Expectation Factor Trauma Outcomes Measure (TEFTOM) questionnaire is a self-administered, patient-rated outcome measurement questionnaire designed to measure both ‘expectation’ and ‘outcome’ in orthopaedic trauma pat…

Medial Open‐wedge Osteotomy with Double‐plate Fixation for Varus Malunion of the Distal Femur Open

Qifang He, Han‐xu Wang, Hui Sun, Yu Zhan, Binbin Zhang , et al. · 2019

Objective To present our clinical experience of treating varus malunion of the distal femur through a medial open‐wedge osteotomy with double‐plate fixation. Methods A prospective cohort study was performed. From January 2005 to February 2…

Locking Plate Use with or without Strut Support for Varus Displaced Proximal Humeral Fractures in Elderly Patients Open

Hongshu Wang, Biyu Rui, Shengdi Lu, Congfeng Luo, Yunfeng Chen , et al. · 2019

Background: Varus displaced fractures of the proximal part of the humerus, particularly in osteoporotic bone, commonly require open reduction and internal fixation. However, surgical treatment methods remain controversial and have shown in…

Tibial plateau fractures in elderly people: an institutional retrospective study Open

Qifang He, Hui Sun, Lin-Yuan Shu, Yu Zhan, Chunyan He , et al. · 2018

Erratum Open

Hai Huang, Heyuan Wang, Guixia Wang, Yufei Gao, Conghai Zhao , et al. · 2018

Erratum Open

Huang Hai, Heyuan Wang, Guixia Wang, Yufei Gao, Conghai Zhao , et al. · 2018

MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting DLL1 and Regulating PI3K/AKT Pathway Open

Wei Zhang, Peichun Hsu, Biao Zhong, Shang Z. Guo, Chi Zhang , et al. · 2018

Background/Aims: Osteoarthritis (OA) is the prevalent degenerative disease caused by various factors. MicroRNAs are important regulators in the inflammation and immune response. The aim of this study was to investigate the effect of microR…

Structure‐based statistical modeling and analysis of peptide affinity and cross‐reactivity to human senile osteoporosis <span>OSF SH3</span> domain Open

Wei Zhang, Biao Zhong, Yulin Zhan, Congfeng Luo · 2017

Human osteoclast‐stimulating factor (OSF) induces osteoclast formation and bone resorption in senile osteoporosis by recruiting multiple signaling complexes with cognate interacting partners through its N‐terminal Src homology 3 (SH3) pept…

miR‐373 regulates inflammatory cytokine‐mediated chondrocyte proliferation in osteoarthritis by targeting the P2X7 receptor Open

Wei Zhang, Biao Zhong, Chi Zhang, Congfeng Luo, Yulin Zhan · 2017

Inflammatory cytokines commonly initiate extreme changes in the synovium and cartilage microenvironment of osteoarthritis ( OA ) patients, which subsequently cause cellular dysfunction, especially in chondrocytes. It has been reported that…

Double-plating fixation of comminuted femoral shaft fractures with concomitant thoracic trauma Open

Tao Cheng, Ronggang Xia, Xiaoyu Yan, Congfeng Luo · 2017

Objective This study was performed to evaluate the clinical outcomes in adult polytraumatized patients with thoracic injury and femoral shaft fractures treated with double-plating fixation. Methods From November 2010 to October 2014, 15 po…

Minimally invasive surgery under fluoro-navigation for anterior pelvic ring fractures Open

Kaihua Zhou, Congfeng Luo, Nong Chen, Chengfang Hu, Fugen Pan · 2016

Results of a modified posterolateral approach for the isolated posterolateral tibial plateau fracture Open

Guanyi Liu, Bai-ping Xiao, Congfeng Luo, Yunqiang Zhuang, Rongming Xu , et al. · 2016

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