Chi‐Tang Ho
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View article: Evaluating the pungency perception of Zanthoxylum armatum DC. oil by facial recognition techniques and machine learning
Evaluating the pungency perception of Zanthoxylum armatum DC. oil by facial recognition techniques and machine learning Open
Zanthoxylum armatum DC. (ZAD) oil is a kind of popular seasoning for its unique flavor and numbing taste. Pungency is characterized as a numbing and stimulating sensation in ZAD oil. This study aimed to objectively assess ZAD oil pungency …
View article: Role of capsaicin, circadian clock genes, and TRPV1 in colorectal carcinogenesis: Lessons and future directions
Role of capsaicin, circadian clock genes, and TRPV1 in colorectal carcinogenesis: Lessons and future directions Open
Disruptions in rhythm-regulating genes, termed circadian misalignment, have been increasingly associated with the progression of colorectal cancer (CRC), a significant global health challenge. Capsaicin (CAP), a bioactive compound found in…
View article: Piceatannol Attenuates Benzo[<i>a</i>]pyrene/DSS-Induced Colorectal Cancer in Mice via Modulation of Gut Microbiota and Inhibition of the PI3K/AKT/mTOR Pathway
Piceatannol Attenuates Benzo[<i>a</i>]pyrene/DSS-Induced Colorectal Cancer in Mice via Modulation of Gut Microbiota and Inhibition of the PI3K/AKT/mTOR Pathway Open
Benzo[a]pyrene (B[a]P) promotes colorectal cancer (CRC) under chronic inflammation. Piceatannol (PIC), a polyphenol with anti-inflammatory properties, was investigated for its timing-dependent effects in a B[a]P/dextran sulfate sodium (DSS…
View article: FILIAL PIETY THROUGH JING SI APHORISMS: PARENTAL INSIGHTS IN TZU CHI DA AI KINDERGARTEN MALAYSIA
FILIAL PIETY THROUGH JING SI APHORISMS: PARENTAL INSIGHTS IN TZU CHI DA AI KINDERGARTEN MALAYSIA Open
In an era of accelerating modernization, conveying filial traditional familial values among younger generations brings challenges in Malaysia's diverse society. Jing Si Aphorisms' teachings, drawn from Tzu Chi's humanistic education, serve…
View article: Upcycling Sugar Mill Byproducts into Policosanols via Supercritical CO<sub>2</sub> and Liquefied Extraction Technologies
Upcycling Sugar Mill Byproducts into Policosanols via Supercritical CO<sub>2</sub> and Liquefied Extraction Technologies Open
Sugarcane leaves and filter mud represent valuable sources of policosanols, a bioactive compound known for its cholesterol-lowering properties. Policosanol extraction efficiency by liquefied dimethyl ether (LDME) was compared with that by …
View article: Nobiletin Modulates Adipocyte-Derived Exosomal miRNA to Improve Liver Lipid Metabolism in Obese Mice
Nobiletin Modulates Adipocyte-Derived Exosomal miRNA to Improve Liver Lipid Metabolism in Obese Mice Open
This study examines the antiobesity properties of nobiletin through its influence on extracellular vesicles, particularly exosomes. Nob-ELVs (nobiletin with adipocyte-derived extracellular vesicles) significantly reduce fat accumulation in…
View article: Unveiling the preventive potential of artesin in brain-heart Axis: In-silico insights into Alzheimer's and cardiovascular diseases prevention
Unveiling the preventive potential of artesin in brain-heart Axis: In-silico insights into Alzheimer's and cardiovascular diseases prevention Open
The brain-heart axis constitutes a critical interface in the pathogenesis of Alzheimer's disease (AD) and cardiovascular disease (CVD), yet no bioactive compound has been definitively identified to modulate both conditions simultaneously. …
View article: Characterizing and decoding the effects of co-culture fermentation on dark tea infusion flavor development: elucidating microbial succession and metabolic dynamics mediated by Eurotium cristatum and water kefir
Characterizing and decoding the effects of co-culture fermentation on dark tea infusion flavor development: elucidating microbial succession and metabolic dynamics mediated by Eurotium cristatum and water kefir Open
Water kefir (a probiotic-rich culture) and Eurotium cristatum (a key fungus in Fu brick tea) were co-fermented with dark tea infusion to investigate dynamic changes in volatile organic compounds (VOCs), microbial communities, and biochemic…
View article: Autonomous Reef Monitoring Structures (ARMS) Reveal Human-Induced Biodiversity Shifts in Urban Coastal Ecosystems
Autonomous Reef Monitoring Structures (ARMS) Reveal Human-Induced Biodiversity Shifts in Urban Coastal Ecosystems Open
Biodiversity thrives in coastal marine habitats which host foundational species such as corals, mangroves, and seagrasses. However, coastal development and the growth of megacities along shorelines impose an array of stressors on the marin…
View article: SysLLMatic: Large Language Models are Software System Optimizers
SysLLMatic: Large Language Models are Software System Optimizers Open
Automatic software system optimization can improve software speed and save energy. Traditional approaches to optimization rely on manual tuning and compiler heuristics, limiting their ability to generalize across diverse codebases. Recent …
View article: 5‐Demethyl‐Polymethoxyflavones Mitigate Obesity by Reducing Adipose Tissue Inflammation, Promoting Browning, and Modulating Gut Microbiota in High‐Fat Diet‐Fed Mice
5‐Demethyl‐Polymethoxyflavones Mitigate Obesity by Reducing Adipose Tissue Inflammation, Promoting Browning, and Modulating Gut Microbiota in High‐Fat Diet‐Fed Mice Open
Given the escalating prevalence of obesity worldwide, identifying efficacious dietary components is crucial. This study investigated whether citrus‐derived 5‐demethyl‐polymethoxyflavones (5‐DPMFs) protect against obesity in high‐fat diet (…
View article: Dynamic Variation of Secondary Metabolites from Polygonatum cyrtonema Hua Rhizomes During Repeated Steaming–Drying Processes
Dynamic Variation of Secondary Metabolites from Polygonatum cyrtonema Hua Rhizomes During Repeated Steaming–Drying Processes Open
Polygonati Rhizoma, widely used as a traditional functional food and herbal medicine, is well known for its health-promoting activities after the process of “nine cycles of steaming-drying”. Based on UPLC-MS/MS, 1369 secondary metabolites …
View article: Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice
Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice Open
Obesity and its associated metabolic disorders─including muscle atrophy─pose significant health challenges, particularly with the increasing prevalence of high-fat diets. This study investigates the effects of nobiletin, a citrus flavonoid…
View article: The regulatory mechanism of intermittent fasting and probiotics on cognitive function by the microbiota‐gut‐brain axis
The regulatory mechanism of intermittent fasting and probiotics on cognitive function by the microbiota‐gut‐brain axis Open
Intermittent fasting (IF) is an eating pattern that promotes health and cognitive improvement through periodic fasting and eating. It has been shown to enhance neuroplasticity and reduce oxidative stress and inflammation. Recent studies ha…
View article: Anti-fibrotic effects of marein-enriched <i>Coreopsis tinctoria</i> flavonoids on CCl <sub>4</sub>-induced hepatic fibrosis in rats <i>via</i> blocking the TGF-β1/Smad signaling pathway
Anti-fibrotic effects of marein-enriched <i>Coreopsis tinctoria</i> flavonoids on CCl <sub>4</sub>-induced hepatic fibrosis in rats <i>via</i> blocking the TGF-β1/Smad signaling pathway Open
Coreopsis tinctoria Nutt., an edible flowering plant, belongs to the Chrysanthemum family and is mainly grown at high altitudes in Northwestern China. It is rich in polyphenolic compounds, particularly marein and flavomarein, and possesses…
View article: Key factors influencing the formation of α-dicarbonyls and dietary advanced glycation end products in bread and commercial bakery products: Impacts of sugar, lipid and gluten protein
Key factors influencing the formation of α-dicarbonyls and dietary advanced glycation end products in bread and commercial bakery products: Impacts of sugar, lipid and gluten protein Open
α-Dicarbonyls and dietary advanced glycation end products (dAGEs) are potentially harmful compounds formed from the Maillard reaction. Bakery products often contain high levels of α-dicarbonyls and dAGEs due to thermal processing. Addition…
View article: Feruloylacetone and Its Analog Demethoxyferuloylacetone Mitigate Obesity-Related Muscle Atrophy and Insulin Resistance in Mice
Feruloylacetone and Its Analog Demethoxyferuloylacetone Mitigate Obesity-Related Muscle Atrophy and Insulin Resistance in Mice Open
Obesity-induced muscle alterations, such as inflammation, metabolic dysregulation, and myosteatosis, lead to a decline in muscle mass and function, often resulting in sarcopenic obesity. Currently, there are no definitive treatments for sa…
View article: Edible 3D printed emulsion gels: Effects of inulin on sensory characteristics and mechanical properties
Edible 3D printed emulsion gels: Effects of inulin on sensory characteristics and mechanical properties Open
Inulin is a prebiotic and an effective texture modifier for emulsion gels, offering considerable commercial value for consumers whose chewing ability changes. This study evaluated the influence of inulin on print precision, structural inte…
View article: Capsaicin‐mediated repair of circadian disruption‐induced Intestinal barrier damage via the gut microbiota
Capsaicin‐mediated repair of circadian disruption‐induced Intestinal barrier damage via the gut microbiota Open
Circadian clock serves as a regulator of gastrointestinal health, and the disruption of circadian rhythm may trigger the dysregulation of the intestinal barrier functions. This study investigated the effectiveness of capsaicin (CAP) in mit…
View article: Antiglycating effects of citrus flavonoids and associated mechanisms
Antiglycating effects of citrus flavonoids and associated mechanisms Open
Glycation of proteins and DNA forms advanced glycation end products (AGEs) causing cell and tissue dysfunction and subsequent various chronic diseases, in particular, metabolic and age-related diseases. Targeted AGE inhibition includes sca…
View article: Crucial textural properties of braised pork to evaluate the oral mastication behavior and its water distribution to influence tenderness
Crucial textural properties of braised pork to evaluate the oral mastication behavior and its water distribution to influence tenderness Open
The complex composition of braised pork, including lean meat, pigskin, and fat, makes it difficult for sensory evaluation of its texture properties. This study investigated the correlation between sensory texture attributes and physicochem…
View article: Ginger essential oil prevents NASH progression by blocking the NLRP3 inflammasome and remodeling the gut microbiota-LPS-TLR4 pathway in mice
Ginger essential oil prevents NASH progression by blocking the NLRP3 inflammasome and remodeling the gut microbiota-LPS-TLR4 pathway in mice Open
This study demonstrated that GEO prevents NASH progression which is probably associated with the alterations of gut microbiota and inhibition of the LPS/TLR4/NF-κB pathway. Hence, GEO may offer a promising application as a dietary suppleme…
View article: Improving the texture of braised pork by gradient-temperature heating and its molecular mechanism
Improving the texture of braised pork by gradient-temperature heating and its molecular mechanism Open
A novel gradient-temperature heating regime was proposed to improve the texture of braised pork. Compared with one-stage pressure heat treatment of around 107 °C, the gradient-temperature heat regime of preheating at 60 °C, followed by a s…