Explanipedia

Cardiac action potential generation mechanisms via an intramembrane photoswitch. A simulation study Open

Ludovica Cestariolo, Chiara Florindi, Chiara Bertarelli, Antonio Zaza, Guglielmo Lanzani , et al. · 2025

Optical stimulation is emerging as a promising alternative to conventional methods for both research and therapeutic purposes due to its advantages, such as reduced energy consumption, minimal invasiveness, and exceptional spatial and temp…

A Conformationally Driven Mechanism in n‐Type Doping of Naphthalene Diimide‐Bithiophene Copolymer by 1H‐Benzimidazoles Open

Simone Cimò, Ilaria Denti, Lorenzo Rossi, Marco Cassinelli, Martina Rossi , et al. · 2025

N‐doped polymer semiconductors are of great interest in the field of organic thermoelectrics, as high‐conductive materials are still highly desired. In this framework, this paper aims to clarify whether the n‐doping of naphthalene diimide‐…

BPS2025 - Investigating the mechanism of cardiac cell excitability modulation by a membrane-targeted photoswitch Open

Chiara Florindi, Ludovica Cestariolo, Vito Vurro, Paola Moretti, Chiara Bertarelli , et al. · 2025

A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina Open

Gaia Ziraldo, Sara Cupini, Valentina Sesti, Emanuela Delfino, Guglielmo Lanzani , et al. · 2025

Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential Open

Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer , et al. · 2025

We introduce a family of membrane-targeted azobenzenes (MTs) with a push-pull character as a new tool for cell stimulation. These molecules are water soluble and spontaneously partition in the cell membrane. Upon light irradiation, they is…

Electrospinning of Polymeric Nanofibers Embedding Halogenated Carbon Atomic Wires Open

Simone Melesi, Piotr Pińkowski, Bartłomiej Pigulski, Nurbey Gulia, Sławomir Szafert , et al. · 2024

Functional modification of graphene nanoparticles: covalent grafting of peptides and π bonding for drug loading and delivery Open

Kaiyue Hu, Luigi Brambilla, P.F. Moretti, Chiara Bertarelli, Chiara Castiglioni , et al. · 2024

Graphene nanoparticles (GNPs) prepared with a green physical method were functionalized with the peptide (R11) or with pyrene. A thorough chemical and structural characterization of the modified GNPs was achieved by spectroscopic technique…

Skeletal muscle cells opto-stimulation by intramembrane molecular transducers - Code Open

Ilaria Venturino, Vito Vurro, Matteo Moschetta, Silvio Bonfadini, Luigino Criante , et al. · 2023

Code used to analysed contracting video

Skeletal muscle cells opto-stimulation by intramembrane molecular transducers Open

Ilaria Venturino, Vito Vurro, Matteo Moschetta, Silvio Bonfadini, Luigino Criante , et al. · 2023

Data of contracting muscle cells upon optical and electrical stimulation

Combining UV-Vis and Resonance Raman Spectroscopy to Characterize Molecular Aggregation Open

Valentina Sesti, Micol D’Antonio, Andrea Lucotti, Paola Moretti, Rossella Castagna , et al. · 2023

In this work, we use UV-Vis and Raman spectroscopy to correlate the intensity of selected transitions to the onset of aggregation phenomena. Through TDDFT calculations, we rationalize the formation of H-aggregates and their influence on th…

Electrospinning of pullulan-based orodispersible films containing sildenafil Open

Elisabetta Ravasi, Alice Melocchi, Alessia Arrigoni, Arianna Chiappa, C.G.M. Gennari , et al. · 2023

High Frequency Solution‐Processed Organic Field‐Effect Transistors with High‐Resolution Printed Short Channels Open

Tommaso Losi, Łukasz Witczak, Mateusz Łysień, Pietro Rossi, Paola Moretti , et al. · 2023

Organic electronics is an emerging technology that enables the fabrication of devices with low‐cost and simple solution‐based processes at room temperature. In particular, it is an ideal candidate for the Internet of Things since devices c…

Development and characterization of crosslinked PPO-based anion exchange membranes for AEM fuel cells Open

Andrea Basso Peressut, Joele Montagna, Paola Moretti, Alessia Arrigoni, Saverio Latorrata , et al. · 2023

Optical modulation of excitation-contraction coupling in human-induced pluripotent stem cell-derived cardiomyocytes Open

Vito Vurro, Beatrice Federici, Carlotta Ronchi, Chiara Florindi, Valentina Sesti , et al. · 2023

Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field that aims to induce light-sensitivity in living systems by exploiting exogeneous phototransducers. Here, we propose an intramembrane photoswitch, based on …

Development of Tailored Graphene Nanoparticles: Preparation, Sorting and Structure Assessment by Complementary Techniques Open

Kaiyue Hu, Luigi Brambilla, Patrizia Sartori, Claudia Moscheni, Cristiana Perrotta , et al. · 2023

We present a thorough structural characterization of Graphene Nano Particles (GNPs) prepared by means of physical procedures, i.e., ball milling and ultra-sonication of high-purity synthetic graphite. UV-vis absorption/extinction spectrosc…

Conducting Electrospun Nanofibres: Monitoring of Iodine Doping of P3HT through Infrared (IRAV) and Raman (RaAV) Polaron Spectroscopic Features Open

Alessia Arrigoni, Luigi Brambilla, Chiara Castiglioni, Chiara Bertarelli · 2022

Aligned polymer nanofibres are prepared by means of the electrospinning of a chlorobenzene solution containing regioregular poly(3-hexyltiophene-2,5-diyl), P3HT, and poly(ethylene oxide), PEO. The PEO scaffold is easily dissolved with acet…

Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes Open

Vito Vurro, Beatrice Federici, Carlotta Ronchi, Chiara Florindi, Valentina Sesti , et al. · 2022

Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field of research that aims to induce light sensitivity in living systems by exploiting exogeneous phototransducers. Here we propose a recently synthetized intra…

Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential Open

Tailise Carolina de Souza‐Guerreiro, Gaia Bondelli, Iago Grobas, Stefano Donini, Valentina Sesti , et al. · 2022

Recent studies have shown that bacterial membrane potential is dynamic and plays signalling roles. Yet, little is still known about the mechanisms of bacterial membrane potential regulation –owing in part to a scarcity of appropriate resea…

Morphology and Intramolecular Interactions in <b>P(VDF-TrFE)</b> Electrospun Nanofibers Doped with Disperse Orange 3 Dye: A Joint Infrared Spectroscopy and Electron Microscopy Study Open

Alessia Arrigoni, Gianluca Serra, Jacopo Manidi, Chiara Bertarelli, Chiara Castiglioni · 2022

In this study, we describe a host-guest system consisting of a push-pull dye, the 4-amino-4'-nitroazobenzene (Disperse Orange 3, DO3), mixed with the copolymer poly(vinylidene fluoride-co-trifluoroethylene) [P(VDF-TrFE)] as a…

Study of the Photoreaction of New Triazene Derivatives in Solution and in Polymer Binder Open

Paola Gallì, Paola Moretti, A Cavalleri, Emma Minelli, Alessandra Zito , et al. · 2022

Azobenzene photoisomerization probes cell membrane nanoviscosity Open

Arianna Magni, Gaia Bondelli, Giuseppe M. Paternò, Samim Sardar, Valentina Sesti , et al. · 2021

The viscosity of cell membranes is a crucial parameter that affects the diffusion of small molecules both across and within the lipidic membrane and that is related to several diseases. Therefore, the possibility to measure quantitatively …

Cyclic allylic sulfide based photopolymer for holographic recording showing high refractive index modulation Open

Paola Gallì, Richard A. Evans, Chiara Bertarelli, Andrea Bianco · 2021

The development and characterization of a new holographic photopolymer system showing high refractive index modulation (∆n) is presented. It exploits the ring‐opening polymerization reaction of a cyclic allylic sulfide (CAS) monomer, which…

New fourier CGH coding using DMD generated masks for grayscale and color images Open

Frédéric Zamkotsian, Luca Oggioni, Giorgio Pariani, Patrick Lanzoni, Chiara Bertarelli , et al. · 2020

International audience

New Fourier CGH coding using DMD generated masks Open

Frédéric Zamkotsian, Giorgio Pariani, Patrick Lanzoni, Luca Oggioni, Chiara Bertarelli , et al. · 2020

International audience

P(VDF-TrFE) nanofibers: structure of the ferroelectric and paraelectric phases through IR and Raman spectroscopies Open

Alessia Arrigoni, Luigi Brambilla, Chiara Bertarelli, Gianluca Serra, Matteo Tommasini , et al. · 2020

This study elucidates the complex morphology and the related spectroscopic response of poly(vinylidene fluoride- co -trifluoroethylene) copolymer, with 80% molar VDF content, namely P(VDF-TrFE) (80/20).

High response photochromic films based on D–A diarylethenes and their application in holography Open

Maria Chiara Mantero, Luca Oggioni, Giorgio Pariani, F. Ortica, S. Tosi , et al. · 2020

Photochromic diarylethenes with D–A structure are good candidates in holography thanks to their very large modulation of the complex refractive index.

Membrane Environment Enables Ultrafast Isomerization of Amphiphilic Azobenzene -INVITED Open

Giuseppe M. Paternò, Elisabetta Colombo, Vito Vurro, Francesco Lodola, Valentina Sesti , et al. · 2020

We report on the isomerization dynamics of an amphiphilic azobenzene that dwells within the plasma membrane. We found that in aggregates formed in water, the isomerization reaction is hindered, while radiative deactivation is favoured. How…

Holography with Photochromic Diarylethenes Open

Luca Oggioni, Giorgio Pariani, Frédéric Zamkotsian, Chiara Bertarelli, Andrea Bianco · 2019

Photochromic materials are attractive for the development of holograms for different reasons: they show a modulation of the complex refractive index, meaning they are suitable for both amplitude and phase holograms; they are self-developin…

A Membrane-Targeted Photoswitch Potently Modulates Neuronal Firing Open

Mattia L. DiFrancesco, Francesco Lodola, Elisabetta Colombo, Luca Maragliano, Giuseppe M. Paternò , et al. · 2019

Optical technologies allowing modulation of neuronal activity at high spatio-temporal resolution are becoming paramount in neuroscience. We engineered novel light-sensitive molecules by adding polar groups to a hydrophobic backbone contain…

Photochromic Polyurethanes Showing a Strong Change of Transparency and Refractive Index Open

Luca Oggioni, Chiara Toccafondi, Giorgio Pariani, Letizia Colella, M. Canepa , et al. · 2017

Photochromic polymers have been studied as rewritable systems for optical elements with tunable transparency in the visible and refractive index in the NIR. Six diarylethene monomers have been synthesized to give thin films of photochromic…

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