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View article: The role of appearance-related comments and interoceptive deficits in eating disorders: an exploratory study in a 1-year cohort of outpatients
The role of appearance-related comments and interoceptive deficits in eating disorders: an exploratory study in a 1-year cohort of outpatients Open
Outpatients who experienced both these factors showed a more severe clinical presentation, particularly in terms of global psychopathology and restrictive symptoms, regardless of any ED diagnosis. The results showed the frequent occurrence…
View article: Hemophagocytic Lymphohistiocytosis in the adult critically ill: a narrative review of case reports and case series
Hemophagocytic Lymphohistiocytosis in the adult critically ill: a narrative review of case reports and case series Open
Background Hemophagocytic Lymphohistiocytosis (HLH) is a rare life-threatening syndrome characterized by hyperinflammation caused by abnormally activated macrophages and cytotoxic T cells overlapping with sepsis and multi-organ disfunction…
View article: Italian Validation of the Accommodation and Enabling Scale for Eating Disorders and Caregiver Skills Scale for Caregivers of Patients With Eating Disorders
Italian Validation of the Accommodation and Enabling Scale for Eating Disorders and Caregiver Skills Scale for Caregivers of Patients With Eating Disorders Open
Objectives Eating disorders (ED) impact caregivers' lives, affecting their mental health and the entire family system. Caregivers often tend to accommodate ED behaviors, structuring family life around ED pathology. Both high levels of acco…
View article: Differences in Personal Recovery Among Individuals with Severe Mental Disorders in Private and Supported Accommodations: An Exploratory Study
Differences in Personal Recovery Among Individuals with Severe Mental Disorders in Private and Supported Accommodations: An Exploratory Study Open
People with severe mental disorders (SMD) face long-term functional impairments requiring integrated, community-based, recovery-oriented care. Italy provides two main housing models for people with SMD: private accommodation (PA) and suppo…
View article: Gender differences in psychological features and determinates of quality of life in axial spondyloarthritis and psoriatic arthritis: a cross-sectional study
Gender differences in psychological features and determinates of quality of life in axial spondyloarthritis and psoriatic arthritis: a cross-sectional study Open
The study indicates that female patients with axial spondyloarthritis and psoriatic arthritis experience worse scores in psychological variables compared to men. Additionally, women's quality of life is significantly lower when compared to…
View article: Differences in Personal Recovery Among Individuals with Severe Mental Disorders in Private and Supported Accommodations: An Exploratory Study
Differences in Personal Recovery Among Individuals with Severe Mental Disorders in Private and Supported Accommodations: An Exploratory Study Open
People with severe mental disorders (SMD) face long-term functional impairments requiring integrated, community-based, recovery-oriented care. Italy provides two main housing models for people with SMD: private accommodation (PA) and suppo…
View article: Peritraumatic Distress Affected the Course of Depressive Symptoms During the COVID-19 Pandemic Lockdown in Subjects with Affective and Anxiety Disorders
Peritraumatic Distress Affected the Course of Depressive Symptoms During the COVID-19 Pandemic Lockdown in Subjects with Affective and Anxiety Disorders Open
In western countries, the COVID-19 pandemic represented a unique scenario of a global threat of contagion of a life-threatening illness, as confirmed by the need for exceptional and never adopted measures represented by national lockdowns.…
View article: A Genome-Wide Association Study of First-Episode Psychosis: A Genetic Exploration in an Italian Cohort
A Genome-Wide Association Study of First-Episode Psychosis: A Genetic Exploration in an Italian Cohort Open
Background: Psychosis, particularly schizophrenia (SZ), is influenced by genetic and environmental factors. The neurodevelopmental hypothesis suggests that genetic factors affect neuronal circuit connectivity during perinatal periods, henc…
View article: Feasibility, Acceptability, and Impact of Recovery-Oriented Practices in an Italian Community Mental Health Service: A Pilot Study
Feasibility, Acceptability, and Impact of Recovery-Oriented Practices in an Italian Community Mental Health Service: A Pilot Study Open
Background: Over the past decade, Italy has made progress in adopting recovery-oriented approaches in mental health care, though full alignment with international guidelines remains incomplete. This study investigates the feasibility, acce…
View article: Assessing the effectiveness and the feasibility of a group-based treatment for self-stigma in people with mental disorders in routine mental health services in North-East Italy: study protocol for a pragmatic multisite randomized controlled trial
Assessing the effectiveness and the feasibility of a group-based treatment for self-stigma in people with mental disorders in routine mental health services in North-East Italy: study protocol for a pragmatic multisite randomized controlled trial Open
ClinicalTrials.gov; Identifier: NCT06567145.
View article: Impact of Multidrug-Resistant Bacteria in a Cohort of COVID-19 Critically Ill Patients: Data from a Prospective Observational Study Conducted in a High-Antimicrobial-Resistance-Prevalence Center
Impact of Multidrug-Resistant Bacteria in a Cohort of COVID-19 Critically Ill Patients: Data from a Prospective Observational Study Conducted in a High-Antimicrobial-Resistance-Prevalence Center Open
Background: Bacterial superinfections are common complications during viral infections, but the impact of multidrug-resistant (MDR) pathogens in critically ill patients affected by coronavirus disease 2019 (COVID-19) is still debated. Meth…
View article: Feasibility and Impact of Recovery-Oriented Practices in an Italian Mental Health Service: A Pilot Study
Feasibility and Impact of Recovery-Oriented Practices in an Italian Mental Health Service: A Pilot Study Open
Background In the last decade, Italy has made progressed in adopting the personal recovery-oriented approach. However, full adherence to international recommendations for implementation remains incomplete. Aims This study aimed to explore …
View article: Early maladaptive schemas mediate the relationship between severe childhood trauma and eating disorder symptoms: evidence from an exploratory study
Early maladaptive schemas mediate the relationship between severe childhood trauma and eating disorder symptoms: evidence from an exploratory study Open
This exploratory study provides preliminary evidence about the importance of early maladaptive schemas in the relationship between trauma history and ED psychopathology. In addition, ED symptoms may represent a dysfunctional attempt to avo…
View article: Gender differences in clinical features and quality of life of patients with axial spondyloarthritis and psoriatic arthritis
Gender differences in clinical features and quality of life of patients with axial spondyloarthritis and psoriatic arthritis Open
Objective. The aim of the current study was to compare the clinical and treatment characteristics and dimensions of health-related quality of life between female and male patients with axial spondyloarthritis (SpA) and psoriatic arthritis …
View article: Unraveling the mechanisms of high-level gait control in functional gait disorders
Unraveling the mechanisms of high-level gait control in functional gait disorders Open
View article: Experienced discrimination and internalized stigma among people infected with SARS‐CoV‐2 and surviving COVID‐19: Association with anxiety, depression, and insomnia symptoms
Experienced discrimination and internalized stigma among people infected with SARS‐CoV‐2 and surviving COVID‐19: Association with anxiety, depression, and insomnia symptoms Open
People surviving COVID‐19 may experience social stigma related to their condition even after clinical recovery. This study aimed to: (1) investigate COVID‐19‐related experienced discrimination and internalized stigma, and (2) explore their…
View article: Nutrient Composition of Four Dietary Patterns in Italy: Results from an Online Survey (the INVITA Study)
Nutrient Composition of Four Dietary Patterns in Italy: Results from an Online Survey (the INVITA Study) Open
Though Italy is a native land of Mediterranean diet, its adherence in the Italian population is low, witnessed by the high rates of overweight in its inhabitants. Vegetarian dietary patterns (i.e., lacto-ovo-vegetarian and vegan) are incre…
View article: Outcomes and Impact of Pre-ECMO Clinical Course in Severe COVID-19-Related ARDS Treated with VV-ECMO: Data from an Italian Referral ECMO Center
Outcomes and Impact of Pre-ECMO Clinical Course in Severe COVID-19-Related ARDS Treated with VV-ECMO: Data from an Italian Referral ECMO Center Open
Background: The efficacy of veno-venous extracorporeal membrane oxygenation (VV-ECMO) as rescue therapy for refractory COVID-19-related ARDS (C-ARDS) is still debated. We describe the cohort of C-ARDS patients treated with VV-ECMO at our E…
View article: Early Maladaptive Schemas Mediate the Relationship between Severe Childhood Trauma and Eating Disorder Symptoms
Early Maladaptive Schemas Mediate the Relationship between Severe Childhood Trauma and Eating Disorder Symptoms Open
Background: Childhood trauma history has frequently been linked to eating disorders (EDs); nevertheless, the scientific literature calls for extending knowledge regarding mediators between EDs and childhood trauma. This study explored whet…
View article: Anticipated and experienced stigma and discrimination in the workplace among individuals with major depressive disorder in 35 countries: qualitative framework analysis of a mixed-method cross-sectional study
Anticipated and experienced stigma and discrimination in the workplace among individuals with major depressive disorder in 35 countries: qualitative framework analysis of a mixed-method cross-sectional study Open
Objectives Workplace stigmatisation and discrimination are significant barriers to accessing employment opportunities, reintegration and promotion in the workforce for people with mental illnesses in comparison to other disabilities. This …
View article: Is self-compassion associated with lower psychological distress in people with long COVID? Results from a cross-sectional survey
Is self-compassion associated with lower psychological distress in people with long COVID? Results from a cross-sectional survey Open
Long COVID affects approximately 10–20% of COVID-19 patients and has a devastating impact on their quality of life and mental health. This study aimed to evaluate symptoms of psychological distress in people with long COVID and explore whe…
View article: Abnormalities of the Descending Inhibitory Nociceptive Pathway in Functional Motor Disorders
Abnormalities of the Descending Inhibitory Nociceptive Pathway in Functional Motor Disorders Open
Background Pain is a common disabling non‐motor symptom affecting patients with functional motor disorders (FMD). Objective We aimed to explore ascending and descending nociceptive pathways with laser evoked potentials (LEPs) in FMD. Metho…
View article: Diets including Animal Food Are Associated with Gastroesophageal Reflux Disease
Diets including Animal Food Are Associated with Gastroesophageal Reflux Disease Open
Gastroesophageal reflux disease (GERD) is a clinical condition with a prevalence of up to 25% in Western countries. Typical GERD symptoms include heartburn and retrosternal regurgitation. Lifestyle modifications, including diet, are consid…
View article: Exploring gender impact on collaborative care planning: insights from a community mental health service study in Italy
Exploring gender impact on collaborative care planning: insights from a community mental health service study in Italy Open
View article: The Role of a Plant-Only (Vegan) Diet in Gastroesophageal Reflux Disease: Online Survey of the Italian General Population
The Role of a Plant-Only (Vegan) Diet in Gastroesophageal Reflux Disease: Online Survey of the Italian General Population Open
The relationship between food and the pathophysiological mechanisms of gastroesophageal reflux disease (GERD) is unclear. There are few data on the impact of dietary habits on GERD symptoms and on the incidence of GERD in subjects undergoi…
View article: Addressing Challenges in Residential Facilities: Promoting Human Rights and Recovery While Pursuing Functional Autonomy
Addressing Challenges in Residential Facilities: Promoting Human Rights and Recovery While Pursuing Functional Autonomy Open
This pilot study suggests that Italian RFs generally aligne with their mission and human rights principles, but personalizing interventions and implementing recovery-oriented practices face challenges.
View article: Differences in Patterns of Stimulant Use and Their Impact on First-Episode Psychosis Incidence: An Analysis of the EUGEI Study
Differences in Patterns of Stimulant Use and Their Impact on First-Episode Psychosis Incidence: An Analysis of the EUGEI Study Open
Background Use of illegal stimulants is associated with an increased risk of psychotic disorder. However, the impact of stimulant use on odds of first-episode psychosis (FEP) remains unclear. Here, we aimed to describe the patterns of stim…
View article: The Impact of COVID-19 Pandemic on Psychiatric Rehabilitation in Residential Facilities: Perspectives of Staff and Residents
The Impact of COVID-19 Pandemic on Psychiatric Rehabilitation in Residential Facilities: Perspectives of Staff and Residents Open
The coronavirus pandemic imposed significant changes in the care of patients in psychiatric residential facilities, especially during lockdown periods. The aim of this study was to assess the impact of the pandemic on patients and staff of…
View article: Identification of an inflammation-associated psychosis onset subgroup by applying unsupervised machine learning to whole-blood expression levels of immune gene transcripts
Identification of an inflammation-associated psychosis onset subgroup by applying unsupervised machine learning to whole-blood expression levels of immune gene transcripts Open
Nowadays, the lack of quantitative criteria to resolve the diagnostic heterogeneity of psychotic onsets limits the development of safer and more effective treatments. Therefore, the hypothesis to integrate multimodal data to uncover biolog…
View article: Effectiveness of mid-regional pro-adrenomedullin, compared to other biomarkers (including lymphocyte subpopulations and immunoglobulins), as a prognostic biomarker in COVID-19 critically ill patients: New evidence from a 15-month observational prospective study
Effectiveness of mid-regional pro-adrenomedullin, compared to other biomarkers (including lymphocyte subpopulations and immunoglobulins), as a prognostic biomarker in COVID-19 critically ill patients: New evidence from a 15-month observational prospective study Open
Background Mid-regional pro-adrenomedullin (MR-proADM), an endothelium-related peptide, is a predictor of death and multi-organ failure in respiratory infections and sepsis and seems to be effective in identifying COVID-19 severe forms. Th…