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View article: “Yes, I Consent!” Prevalence and Role of Guardianship in Older Inpatients: Findings From an Italian Multicenter Survey
“Yes, I Consent!” Prevalence and Role of Guardianship in Older Inpatients: Findings From an Italian Multicenter Survey Open
A significant gap between the need for and use of legal guardianship emerged. Enhancing caregiver education is crucial to protect older adults' rights and autonomy.
View article: Sex and the Multidimensional Prognostic Index in 3.5-year post-COVID-19 mortality among older adults: evidence of a time-varying effect
Sex and the Multidimensional Prognostic Index in 3.5-year post-COVID-19 mortality among older adults: evidence of a time-varying effect Open
Purpose The long-term prognostic impact of frailty in older adults recovering from COVID-19 remains underexplored. The Multidimensional Prognostic Index (MPI) has shown utility in predicting short-term outcomes, but its role over extended …
View article: Influence of sex and gender-related factors on the knowledge of generic medicines among older patients and caregivers
Influence of sex and gender-related factors on the knowledge of generic medicines among older patients and caregivers Open
Generic medicines (GMs) are bioequivalent to brand-name medicines and more cost-effective, yet their use is limited. Gender-related factors may influence attitudes toward GMs, but data on older adults are scarce. This study aimed to explor…
View article: Hip Fracture Geriatric (HIP-G) Index: Predicting 12-Month Mortality in Older Adults With Hip Fracture
Hip Fracture Geriatric (HIP-G) Index: Predicting 12-Month Mortality in Older Adults With Hip Fracture Open
The HIP-G Index is a valid, user-friendly tool for predicting 1-year mortality in older adults with hip fracture and may support decision making in time-constrained clinical settings.
View article: Changes in Geriatric Depression Scale scores in relation to physical performance, inflammatory status, and hippocampal atrophy over a 7-year follow-up: Data from the Pro.V.A. study
Changes in Geriatric Depression Scale scores in relation to physical performance, inflammatory status, and hippocampal atrophy over a 7-year follow-up: Data from the Pro.V.A. study Open
Physical performance measures are associated with GDS scores. While this relationship warrants further exploration, monitoring physical function may serve as a valuable intervention target for improving mental health in older adults.
View article: Body composition, bone mineral density, and functional impairment in axial spondyloarthritis: a 36-month longitudinal study
Body composition, bone mineral density, and functional impairment in axial spondyloarthritis: a 36-month longitudinal study Open
View article: Socioeconomic status modifies the association between adherence to the Mediterranean diet and cognitive outcomes: results from the Collaborative PROMED-COG Pooled Cohorts Study
Socioeconomic status modifies the association between adherence to the Mediterranean diet and cognitive outcomes: results from the Collaborative PROMED-COG Pooled Cohorts Study Open
Background This study examines whether adherence to the Mediterranean diet (MD), alone and combined with physical activity (MedEx), is associated with cognitive decline and dementia incidence, with socioeconomic status (SES) as a potential…
View article: The stress-responsive cytokine GDF-15 and sarcopenia: A systematic review and meta-analysis on aging muscle decline
The stress-responsive cytokine GDF-15 and sarcopenia: A systematic review and meta-analysis on aging muscle decline Open
Sarcopenic individuals had higher circulating GDF-15. Together with the inverse correlation between GDF-15 and muscle mass observed, these findings show a small-to-moderate association between elevated GDF-15 and sarcopenic phenotypes in o…
View article: Impact of a four-domain intrinsic capacity measure on falls: findings from the EPOSA study
Impact of a four-domain intrinsic capacity measure on falls: findings from the EPOSA study Open
Objective Low Intrinsic Capacity (IC) has been associated with adverse health outcomes in older adults, including falls. This study examines a four-domain measure of IC (cognition, psychological, locomotion, vitality) and its relationship …
View article: Correction: Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study
Correction: Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study Open
[This corrects the article DOI: 10.3389/fnut.2025.1640407.].
View article: Feasibility and Potential Effects of Multidomain Interventions to Improve the Cognitive and Functional Well-Being of Elderly Individuals in Residential Structures: The I-COUNT Pilot Study Protocol
Feasibility and Potential Effects of Multidomain Interventions to Improve the Cognitive and Functional Well-Being of Elderly Individuals in Residential Structures: The I-COUNT Pilot Study Protocol Open
Background/Objectives: Multidisciplinary approaches spanning the physical, cognitive, and social domains of geriatric evaluation are essential to promote functional well-being and reduce the aversive consequences of aging. The main objecti…
View article: Age-dependent bone mineral density responses to gender-affirming hormone therapy in transgender individuals: a one-year prospective study
Age-dependent bone mineral density responses to gender-affirming hormone therapy in transgender individuals: a one-year prospective study Open
View article: The Impact of Atrial Fibrillation on Physical Performance in Older Adults: A Longitudinal Study in Relation to Cognitive Function
The Impact of Atrial Fibrillation on Physical Performance in Older Adults: A Longitudinal Study in Relation to Cognitive Function Open
AF impacts physical performance, notably walking speed and handgrip strength, varying by cognitive decline and sex. Multidisciplinary interventions, including optimized AF management and geriatric care strategies, are crucial for preservin…
View article: Beyond Treatment Decisions: The Predictive Value of Comprehensive Geriatric Assessment in Older Cancer Patients
Beyond Treatment Decisions: The Predictive Value of Comprehensive Geriatric Assessment in Older Cancer Patients Open
Background: Comprehensive Geriatric Assessment (CGA) is essential for evaluating older cancer patients, but significant gaps persist in both research and clinical practice. This study aimed (I) to identify the CGA elements that most influe…
View article: Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study
Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study Open
Background and Aims The bioelectrical impedance vector analysis (BIVA) requires population-specific references to correctly classify individuals based on body composition properties. The aim of this study was: (i) to develop new references…
View article: Body weight trajectories from midlife are associated with cognitive decline in advanced age
Body weight trajectories from midlife are associated with cognitive decline in advanced age Open
View article: The interplay of caregiver-patient interactions: Investigating the relationship between burden, anosognosia, and coping strategies
The interplay of caregiver-patient interactions: Investigating the relationship between burden, anosognosia, and coping strategies Open
Dementia significantly burdens caregivers, increasing depressive and anxious symptoms. This impact is influenced by patient characteristics, anosognosia, and caregiver coping strategies. This study aims to analyze these factors and their r…
View article: Improving care for individuals with gender incongruence: Establishing a multidisciplinary approach in Italy
Improving care for individuals with gender incongruence: Establishing a multidisciplinary approach in Italy Open
Purpose To present a multidisciplinary care model designed to provide personalized gender-affirming care and assess general health for transgender and gender-diverse (TGD) individuals. Methods Drawing from our experience in a tertiary cent…
View article: Progression of cognitive decline in older adult patients with dementia: the role of atrial fibrillation and oral anticoagulant therapy
Progression of cognitive decline in older adult patients with dementia: the role of atrial fibrillation and oral anticoagulant therapy Open
View article: Association of Alzheimer's Disease Blood Biomarkers With Sarcopenia Incidence and Progression: A 12‐Year Population‐Based Study
Association of Alzheimer's Disease Blood Biomarkers With Sarcopenia Incidence and Progression: A 12‐Year Population‐Based Study Open
Background Sarcopenia is a complex and multifactorial condition, and recent studies have explored the role of neurological markers in its diagnosis and prediction. Although associations have been identified between reduced muscle strength,…
View article: Frailty increases the risk of hospitalization for atrial fibrillation in older adults: a population-based cohort study
Frailty increases the risk of hospitalization for atrial fibrillation in older adults: a population-based cohort study Open
View article: Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service
Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service Open
Background Osteoporosis is a chronic condition characterized by increased fracture risk. Fragility fractures, especially hip fractures, represent a significant health and economic burden due to population aging. Despite the efficacy of app…
View article: Sex-based differences in glycaemic variability and clinical outcomes among older inpatients with type 2 diabetes: insights from the GLIMPACT study
Sex-based differences in glycaemic variability and clinical outcomes among older inpatients with type 2 diabetes: insights from the GLIMPACT study Open
Methods A retrospective study of patients with type 2 diabetes aged 65 or older, admitted to the Geriatrics Unit of Padua University Hospital between January 2018 and December 2020. We recorded sociodemographic data, blood tests, multidime…
View article: The impact of age and frailty on hospitalization and survival in older liver transplant recipients: a longitudinal cohort study
The impact of age and frailty on hospitalization and survival in older liver transplant recipients: a longitudinal cohort study Open
Purpose Frailty is a well-established risk factor for adverse outcomes, particularly in liver transplant candidates. This study investigates the impact of age and frailty on key clinical outcomes—hospitalizations, waitlist survival, and po…
View article: Impact of vitamin D levels on mortality in older covid-19 vaccinated patients
Impact of vitamin D levels on mortality in older covid-19 vaccinated patients Open
Background Vitamin D plays a key role in regulating the immune system and vaccine response, and hypovitaminosis D is a known risk factor for mortality. However, its potential influence on mortality in SARS-CoV-2 vaccinated older adults rem…
View article: Cognitive cerebellum dominates motor cerebellum in functional decline of older adults with mild cognitive impairment
Cognitive cerebellum dominates motor cerebellum in functional decline of older adults with mild cognitive impairment Open
Objectives The present study aims to investigate the role that cognitive cerebellar lobules, compared to the motor ones, could have on performance abilities control in older individuals with Mild Cognitive Impairment (MCI). Methods Thirty-…
View article: The correlation between bone mineral density measured at the forearm and at the lumbar spine or femoral neck: a systematic review and meta-analysis
The correlation between bone mineral density measured at the forearm and at the lumbar spine or femoral neck: a systematic review and meta-analysis Open
Background Current guidelines for osteoporosis diagnosis do not recommend forearm dual-energy X-ray absorptiometry (DXA) as a standard tool, except in specific cases. This systematic review and meta-analysis investigates the potential corr…
View article: EEG Markers of Improved Proprioception and Posture in Older Women With Osteoporosis
EEG Markers of Improved Proprioception and Posture in Older Women With Osteoporosis Open
The age-related decline in proprioception contributes to poor balance and motor coordination, increasing the risk of falls. Ten female participants (>65 years) with osteoporosis underwent the Mini Balance Evaluation System test before (T0)…
View article: Influence of Sex and Gender on Knowledge of Generic Medicines Among Older Patients and Caregivers
Influence of Sex and Gender on Knowledge of Generic Medicines Among Older Patients and Caregivers Open
Purpose Generic medicines (GMs) are bioequivalent to brand-name drugs and more cost-effective, yet their use is limited. Gender-related factors may influence attitudes towards GMs, but data on older adults are scarce. This study aimed to e…
View article: Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy
Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy Open
Introduction Higher stress levels are linked to increased body fat and decreased bone density, effects that can be exacerbated by lifestyle choices. This is particularly relevant for transgender and gender diverse (TGD) individuals, who of…