Chiara Forastieri
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View article: A striosomal accumbens pathway drives stereotyped behavior through an aversive Esr1+ hypothalamic-habenula circuit
A striosomal accumbens pathway drives stereotyped behavior through an aversive Esr1+ hypothalamic-habenula circuit Open
The lateral hypothalamic area (LHA) integrates external stimuli with internal states to drive the choice between competing innate or value-driven motivated behaviors. Here, we define a striosomal Tac1+/Tshz1+/Oprm1+ neuron subtype in the n…
View article: A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit
A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit Open
The lateral hypothalamic area (LHA) integrates external stimuli with internal states to drive the choice between competing innate or value-driven motivated behaviors. Projections from the LHA to the lateral habenula (LHb) shape internal st…
View article: A comprehensive protocol for efficient differentiation of human NPCs into electrically competent neurons
A comprehensive protocol for efficient differentiation of human NPCs into electrically competent neurons Open
Our protocol provides clear instructions for generating reliable human neuronal cultures with defined electrophysiological properties to investigate neuronal differentiation and model diseases in vitro.
View article: Preclinical and clinical evidence on the approach-avoidance conflict evaluation as an integrative tool for psychopathology – CORRIGENDUM
Preclinical and clinical evidence on the approach-avoidance conflict evaluation as an integrative tool for psychopathology – CORRIGENDUM Open
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View article: Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism Open
The histone demethylase KDM1A is a multi-faceted regulator of vital developmental processes, including mesodermal and cardiac tube formation during gastrulation. However, it is unknown whether the fine-tuning of KDM1A splicing isoforms, al…
View article: Preclinical and clinical evidence on the approach-avoidance conflict evaluation as an integrative tool for psychopathology
Preclinical and clinical evidence on the approach-avoidance conflict evaluation as an integrative tool for psychopathology Open
The approach-avoidance conflict (AAC), i.e. the competing tendencies to undertake goal-directed actions or to withdraw from everyday life challenges, stands at the basis of humans' existence defining behavioural and personality domains. Gr…
View article: ROLE OF LSD1 IN AGING- AND STRESS- DEPENDENT EPIGENETIC DRIFT LEADING TO DEPRESSION AND ANXIETY DISORDERS
ROLE OF LSD1 IN AGING- AND STRESS- DEPENDENT EPIGENETIC DRIFT LEADING TO DEPRESSION AND ANXIETY DISORDERS Open
tutor: E. BATTAGLIOLI ; supervisor: F. RUSCONI ; phd coordinator: M. LOCATI, N. LANDSBERGER
View article: LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse
LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse Open
View article: Rationale, Relevance, and Limits of Stress-Induced Psychopathology in Rodents as Models for Psychiatry Research: An Introductory Overview
Rationale, Relevance, and Limits of Stress-Induced Psychopathology in Rodents as Models for Psychiatry Research: An Introductory Overview Open
Emotional and cognitive information processing represent higher-order brain functions. They require coordinated interaction of specialized brain areas via a complex spatial and temporal equilibrium among neuronal cell-autonomous, circuitry…
View article: Termination of acute stress response by the endocannabinoid system is regulated through lysine‐specific demethylase 1‐mediated transcriptional repression of 2‐AG hydrolases ABHD6 and MAGL
Termination of acute stress response by the endocannabinoid system is regulated through lysine‐specific demethylase 1‐mediated transcriptional repression of 2‐AG hydrolases ABHD6 and MAGL Open
Acute environmental stress rarely implies long‐lasting neurophysiological and behavioral alterations. On the contrary, chronic stress exerts a potent toxic effect at the glutamatergic synapse whose altered physiology has been recognized as…
View article: SRF and SRFΔ5 Splicing Isoform Recruit Corepressor LSD1/KDM1A Modifying Structural Neuroplasticity and Environmental Stress Response
SRF and SRFΔ5 Splicing Isoform Recruit Corepressor LSD1/KDM1A Modifying Structural Neuroplasticity and Environmental Stress Response Open