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View article: Thermal water inhalation for allergic rhinitis and recurrent respiratory infections: a narrative review of the evidence
Thermal water inhalation for allergic rhinitis and recurrent respiratory infections: a narrative review of the evidence Open
Allergic rhinitis (AR) and recurrent respiratory infections (RRIs) are common conditions that significantly impact quality of life and healthcare systems. Thermal water inhalation therapies have emerged as a potential non-pharmacological o…
View article: Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review
Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review Open
Allergic diseases share a type 2 immune reaction and elevated oxidative stress, contributing to disease pathogenesis and exacerbations. Vitamin C (ascorbic acid), a fundamental exogenous antioxidant, has been hypothesized to attenuate thes…
View article: Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review
Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review Open
Quercetin, a natural flavonoid, present in various vegetables and fruits, has garnered increasing attraction for its potential antiallergic properties. Its broad-spectrum activity depends on its anti-inflammatory, immunomodulatory, and ant…
View article: Visual Analog Scale for Asthma and Rhinitis Symptoms: Different Approaches of Measurement
Visual Analog Scale for Asthma and Rhinitis Symptoms: Different Approaches of Measurement Open
View article: Effects of the supplementation of single and multi-strain probiotics, alone or in combination with other treatments, on asthma in children: A systematic review of the randomized, placebo-controlled clinical studies
Effects of the supplementation of single and multi-strain probiotics, alone or in combination with other treatments, on asthma in children: A systematic review of the randomized, placebo-controlled clinical studies Open
Gut microbiota plays an important role in maintaining respiratory health while providing protection against respiratory illnesses. However, the clinical role of probiotic strains in prevention and treatment of early-onset asthma is still d…
View article: A review of clinical and preclinical data supporting a role for resveratrol in the treatment of common respiratory tract pathogens
A review of clinical and preclinical data supporting a role for resveratrol in the treatment of common respiratory tract pathogens Open
Respiratory infections are a relevant issue during infancy and childhood, constituting a major source of morbidity and imposing a substantial burden on healthcare systems. Conditions such as bronchiolitis, pneumonia, and influenza exemplif…
View article: Resveratrol: immunological activity and possible application in children and adolescents with allergic rhinitis
Resveratrol: immunological activity and possible application in children and adolescents with allergic rhinitis Open
View article: Intersocietal survey on real-world asthma management in Italian children
Intersocietal survey on real-world asthma management in Italian children Open
Pediatric asthma management is a compelling challenge for every pediatrician. Different aspects require attention and definition. The present Intersocietal Survey aimed to collect real-world experiences from a sample of Italian pediatricia…
View article: Attitude to food supplement use: a survey promoted by the Italian Society of Pediatric Allergy and Immunology
Attitude to food supplement use: a survey promoted by the Italian Society of Pediatric Allergy and Immunology Open
Food supplements are defined as foodstuffs the purpose of which is to supplement the normal diet and which are concentrated sources of nutrients or other substances with a nutritional or physiological effect, often referred to as nutraceut…
View article: Exploring the Role of Lactoferrin in Managing Allergic Airway Diseases among Children: Unrevealing a Potential Breakthrough
Exploring the Role of Lactoferrin in Managing Allergic Airway Diseases among Children: Unrevealing a Potential Breakthrough Open
The prevalence of allergic diseases has dramatically increased among children in recent decades. These conditions significantly impact the quality of life of allergic children and their families. Lactoferrin, a multifunctional glycoprotein…
View article: Critical reappraisal of short-acting bronchodilators for pediatric respiratory diseases
Critical reappraisal of short-acting bronchodilators for pediatric respiratory diseases Open
View article: Clinical characteristics and diagnostic workup in severe asthma: data from the database of the Italian Pediatric Respiratory Society
Clinical characteristics and diagnostic workup in severe asthma: data from the database of the Italian Pediatric Respiratory Society Open
Although rare in children, severe asthma is responsible for a heavy burden on families and society. Being a rare condition, every center follows only a limited number of patients, and there is a solid rationale for setting up networks to c…
View article: Certainty and uncertainty in the biological activities of resveratrol
Certainty and uncertainty in the biological activities of resveratrol Open
Resveratrol is a nonflavonoid polyphenolic compound with a chemical structure consisting of two aromatic rings linked by a methylene bridge. It exists in two primary isomers and has a broad range of desirable biological activities, includi…
View article: Assessment of Symptom Perception by Visual Analog Scale in Children with Newly-Diagnosed Allergic Rhinitis: The Link with Asthma
Assessment of Symptom Perception by Visual Analog Scale in Children with Newly-Diagnosed Allergic Rhinitis: The Link with Asthma Open
Background: Patients with allergic rhinitis (AR) have bothersome symptoms that may assess using the visual analog scale (VAS). Asthma frequently is associated with AR. The present study investigated the role of VAS in children with newly-d…
View article: Proteomic profiling of extracellular vesicles in synovial fluid and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients reveals novel immunopathogenic biomarkers
Proteomic profiling of extracellular vesicles in synovial fluid and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients reveals novel immunopathogenic biomarkers Open
Introduction New early low-invasive biomarkers are demanded for the management of Oligoarticular Juvenile Idiopathic Arthritis (OJIA), the most common chronic pediatric rheumatic disease in Western countries and a leading cause of disabili…
View article: Molecular Allergy Diagnostics in Children with Cow’s Milk Allergy: Prediction of Oral Food Challenge Response in Clinical Practice
Molecular Allergy Diagnostics in Children with Cow’s Milk Allergy: Prediction of Oral Food Challenge Response in Clinical Practice Open
Background. Cow’s milk allergy (CMA) is the most common food allergy in early childhood. Children with CMA require a precise and punctual diagnosis. Oral food challenge (OFC) is the gold-standard procedure for diagnosing allergies, but it …
View article: Paediatric rheumatologists do not score the physician’s global assessment of juvenile idiopathic arthritis disease activity in the same way
Paediatric rheumatologists do not score the physician’s global assessment of juvenile idiopathic arthritis disease activity in the same way Open
Objectives To assess the heterogeneity in factors affecting physician’s global assessment of disease activity (PhGA) and in PhGA scoring of multiple JIA patient’s case scenarios. Methods An electronic web-based questionnaire of factors pot…
View article: Extracellular vesicle‐derived microRNAs as potential biomarkers in oligoarticular juvenile idiopathic arthritis patients: methodological challenges and new perspectives
Extracellular vesicle‐derived microRNAs as potential biomarkers in oligoarticular juvenile idiopathic arthritis patients: methodological challenges and new perspectives Open
View article: Pediatric SARS-CoV-2–Related Diplopia and Mesencephalic Abnormalities
Pediatric SARS-CoV-2–Related Diplopia and Mesencephalic Abnormalities Open
This report expands the spectrum of pediatric COVID-19-associated neurologic symptoms and highlights a possible isolated neurologic COVID-19-related symptom.
View article: OP0215 WHAT DOES THE PATIENT WELL-BEING VAS TELL US WHEN THE PHYSICIAN GLOBAL ASSESSMENT SCORE IS ZERO? ANALYSIS OF A LARGE MULTINATIONAL DATASET
OP0215 WHAT DOES THE PATIENT WELL-BEING VAS TELL US WHEN THE PHYSICIAN GLOBAL ASSESSMENT SCORE IS ZERO? ANALYSIS OF A LARGE MULTINATIONAL DATASET Open
View article: Proteomics and Extracellular Vesicles as Novel Biomarker Sources in Peritoneal Dialysis in Children
Proteomics and Extracellular Vesicles as Novel Biomarker Sources in Peritoneal Dialysis in Children Open
Peritoneal dialysis (PD) represents the dialysis modality of choice for pediatric patients with end-stage kidney disease. Indeed, compared with hemodialysis (HD), it offers many advantages, including more flexibility, reduction of the risk…
View article: Validity and Reliability of Four Parent/Patient–Reported Outcome Measures for Juvenile Idiopathic Arthritis Remote Monitoring
Validity and Reliability of Four Parent/Patient–Reported Outcome Measures for Juvenile Idiopathic Arthritis Remote Monitoring Open
Objective The aim of this work was to provide evidence of validity and reliability for 4 parent/child–reported outcome measures included in the Outcome Measures in Rheumatology juvenile idiopathic arthritis core domain set: the evaluation …
View article: Childhood multisystem inflammatory syndrome associated with COVID‐19 (MIS‐C): Distinct from Kawasaki disease or part of the same spectrum?
Childhood multisystem inflammatory syndrome associated with COVID‐19 (MIS‐C): Distinct from Kawasaki disease or part of the same spectrum? Open
One of the most challenging and intriguing phenomena observed during the COVID‐19 pandemic has been the multisystem inflammatory syndrome in children (MIS‐C). Patients with this condition present with some clinical features similar to thos…
View article: Definition and Validation of the American College of Rheumatology 2021 Juvenile Arthritis Disease Activity Score Cutoffs for Disease Activity States in Juvenile Idiopathic Arthritis
Definition and Validation of the American College of Rheumatology 2021 Juvenile Arthritis Disease Activity Score Cutoffs for Disease Activity States in Juvenile Idiopathic Arthritis Open
Objective To develop and validate new Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activit…
View article: SAT0669 DISCRIMINANT ABILITY OF THE PARENT VERSION OF THE JUVENILE ARTHRITIS DISEASE ACTIVITY SCORE IN A LARGE MULTINATION COHORT OF PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS
SAT0669 DISCRIMINANT ABILITY OF THE PARENT VERSION OF THE JUVENILE ARTHRITIS DISEASE ACTIVITY SCORE IN A LARGE MULTINATION COHORT OF PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS Open