Chieko Huber
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The claustrum is critical for maintaining working memory information Open
Working memory (WM) is an essential cognitive function allowing the brain to temporarily hold and manipulate information. Rather than residing in a single store, information is believed to be maintained in a distributed network spanning co…
The claustrum is critical for maintaining working memory information Open
Working memory (WM) enables the mammalian brain to temporarily store and manipulate information, supporting cognitive tasks and communication processes 1,2 . Rather than depending on a single specialized area, WM is thought to operate thro…
View article: <i>NOS1</i> mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice
<i>NOS1</i> mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice Open
The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for reproduction. We hypothesized that a disruption of neuronal …
Superior Colliculus to VTA pathway controls orienting response and influences social interaction in mice Open
Abstract Social behaviours characterize cooperative, mutualistic, aggressive or parental interactions that occur among conspecifics. Although the Ventral Tegmental Area (VTA) has been identified as a key substrate for social behaviours, th…
The claustrum-medial prefrontal cortex network controls attentional set-shifting Open
SUMMARY In various mental disorders, dysfunction of the prefrontal cortex contributes to cognitive deficits. Here we studied how the claustrum (CLA), a nucleus sharing reciprocal connections with the cortex, may participate in these cognit…
Microendoscopic imaging of functional responses of claustral neurons during behavior Open
The claustrum is a brain structure that is identified in most mammalian species but little experimental evidence supports its hypothetical functions, resulting from the difficulty to specifically manipulate claustral activities without aff…