Chikang Wang
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View article: Associations Between PFAS Exposure and HPG Axis Hormones in U.S. Women
Associations Between PFAS Exposure and HPG Axis Hormones in U.S. Women Open
Purpose: This study aimed to investigate the associations between serum per- and polyfluoroalkyl substances (PFAS) and reproductive hormones, including follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), estradiol, and proges…
View article: Association Between Serum per- and Polyfluoroalkyl Substances and Iron Status Biomarkers in a Representative Sample of U.S. Adults: NHANES 2013–2018
Association Between Serum per- and Polyfluoroalkyl Substances and Iron Status Biomarkers in a Representative Sample of U.S. Adults: NHANES 2013–2018 Open
Purpose: Per- and polyfluoroalkyl substances (PFAS) comprise a class of man-made compounds widely utilized in manufacturing everyday consumer products. Experimental studies indicate that PFAS may interfere with iron regulation by hindering…
Urinary Glyphosate Concentrations and Serum Sex Hormones in a Nationally Representative U.S. Sample: NHANES 2017–2018 Open
Glyphosate and glyphosate-based herbicides (GBHS) are the most widely used herbicides worldwide, yet their potential endocrine-disrupting effects in humans remain inadequately studied. We analyzed data from 1532 participants aged ≥6 years …
Correlation between urinary glyphosate levels and serum antioxidant vitamins and carotenoids in a representative sample of U.S. adults: NHANES 2017–2018 Open
Glyphosate and glyphosate-based herbicides (GBH) are linked to various health concerns. Prior experimental studies have hinted at their potential to trigger health issues through increased oxidative stress, with some evidence from epidemio…
View article: Investigating the associations of blood lead and cadmium with smoking-related DNA methylation and mortality among U.S. adults
Investigating the associations of blood lead and cadmium with smoking-related DNA methylation and mortality among U.S. adults Open
Drawing from a nationally representative cohort of older U.S. adults, this study provides robust evidence linking blood lead and cadmium levels to smoking-related DNAm and increased mortality risk. Moreover, the analysis revealed additive …
Glyphosate Exposure, Oxidative Stress, Mitochondrial Dysfunction, and Mortality Risk in US Adults: Insights from the National Health and Nutrition Examination Survey Open
Purpose: Glyphosate and glyphosate-based herbicides (GBHs) are widely used across the globe. Experimental research indicates that these herbicides may elevate oxidative stress and impair mitochondrial function. However, the relationship be…
View article: Urinary glyphosate, selenium status, and their impact on mortality: Evidence from NHANES 2013–2018
Urinary glyphosate, selenium status, and their impact on mortality: Evidence from NHANES 2013–2018 Open
In this comprehensive analysis of NHANES data, our study identifies a potentially harmful relationship between glyphosate exposure and whole blood selenium levels. Notably, excessively high whole blood selenium levels may not only reduce t…
Positive Correlation Between Serum Limonene Levels and Muscle Health in a Representative Adult Population in the United States Open
Background/Objectives: Monoterpenes, a class of organic compounds with the molecular formula C10H16, have garnered significant attention for their potential medicinal benefits. Emerging evidence suggests they may positively influence skele…
Associations of Serum Cystatin C, DNAm Cystatin C, Renal Function, and Mortality in U.S. Adults Open
Serum cystatin C is a well-established marker of renal function and a valuable predictor of health risks and mortality. DNA methylation-predicted cystatin C (DNAmCystatinC), an advanced epigenetic biomarker, serves as a proxy for serum cys…
Correlation of Urinary Glyphosate Levels with Whole Blood Selenium Levels among a Representative Sample of US Adults: NHANES 2013-2018 Open
Purpose: Glyphosate and glyphosate-based herbicides (GBH), extensively utilized as herbicides worldwide, have been associated with numerous health issues. Previous experimental studies have indicated their potential to disrupt selenium hom…
Association of urinary glyphosate levels with iron homeostasis among a representative sample of US adults: NHANES 2013–2018 Open
Higher glyphosate exposure is associated with reduced iron availability, suggesting potential disruptions in iron absorption. These findings underscore the need for further research into the health implications of glyphosate exposure on ir…
The relationship between serum monoterpene levels and bone health: a retrospective cross-sectional analysis from the National Health and Nutrition Examination Survey (NHANES) data Open
Introduction Monoterpenes, a subset of the terpene family composed of two isoprene units, have garnered significant attention in research circles owing to their potential medicinal benefits. Recent experimental studies indicate that they m…
View article: Examining the impact of polyfluoroalkyl substance exposure on erythrocyte profiles and its related nutrients: Insights from a prospective study on young Taiwanese
Examining the impact of polyfluoroalkyl substance exposure on erythrocyte profiles and its related nutrients: Insights from a prospective study on young Taiwanese Open
Per- and polyfluoroalkyl substances (PFAS) constitute a group of synthetic chemicals extensively utilized across various commonplace products. PFAS are known to have various toxic effects on human health. The relationship between PFAS expo…
Correlation of Urinary Glyphosate Levels with Whole Blood Selenium Levels among a Representative Sample of US Adults: NHANES 2013-2018 Open
Purpose: Glyphosate and glyphosate-based herbicides (GBH), extensively utilized as herbicides worldwide, have been associated with numerous health issues. Previous experimental studies have indicated their potential to disrupt selenium hom…
Biomonitoring Serum Levels of Three Monoterpenes and Their Association with Liver Function Tests in US adults: NHANES 2013-2014 Open
Purpose Monoterpenes are organic compounds that have been extensively researched for their medicinal benefits. However, experimental evidence has raised concerns about their adverse effects on liver. Despite this, the impact of monoterpene…
Association between urinary glyphosate levels and hand grip strength in a representative sample of US adults: NHANES 2013–2014 Open
Introduction Glyphosate, a widely utilized herbicide globally, has been linked to various health issues, including cancer, birth abnormalities, and reproductive issues. Additionally, there is growing experimental support indicating potenti…
Association between Serum Monoterpene Levels, Hand Grip Strength, and Lean Muscle Mass in a Representative Sample of US Adults: NHANES 2013- 2014 Open
Background Monoterpenes, a class of organic compounds with the molecular formula C10H16, have been the subject of considerable research due to their promising medicinal properties. Recent experiments suggest that they may have beneficial e…
Serum monoterpene levels, glucose homeostasis, lipid profiles, and metabolic syndrome in adults: NHANES, 2013–2014 Open
Monoterpenes are organic compounds which have been studied for their medicinal benefits. However, the association between monoterpene exposure and metabolic parameters in humans is unknown. We investigated the connection between three spec…
View article: The Association among Urinary Lead and Cadmium, Serum Adiponectin, and Serum Apoptotic Microparticles in a Young Taiwanese Population
The Association among Urinary Lead and Cadmium, Serum Adiponectin, and Serum Apoptotic Microparticles in a Young Taiwanese Population Open
Previous studies reported that lead (Pb) and cadmium (Cd) exposure are linked to changes in serum adiponectin; an adipokine that promotes glycolysis and inhibits gluconeogenesis to regulate glucose metabolism. However, no study has ever ex…
The association among urinary lead and cadmium, serum adiponectin, and serum apoptotic microparticles in a young Taiwanese population Open
BACKGROUND AND AIM: Previous studies reported lead (Pb) and cadmium (Cd) exposure has been linked to changes in serum adiponectin. However, no study ever explored the relationship between these two heavy metals exposure and adiponectin in …
View article: The Association between 4-Tertiary-Octylphenol, Apoptotic Microparticles, and Carotid Intima-Media Thickness in a Young Taiwanese Population
The Association between 4-Tertiary-Octylphenol, Apoptotic Microparticles, and Carotid Intima-Media Thickness in a Young Taiwanese Population Open
As one of the most common alkylphenols, 4-tertiary-octylphenol (4-tOP) is commonly used in many consumer products. Our previous epidemiological study revealed a negative correlation between serum 4-tOP levels and carotid intima-media thick…
Association between Glyphosate Exposure and Erythrograms in a Representative Sample of US Adults: NHANES 2013-2014 Open
Glyphosate, being the most commonly utilized herbicide globally, and a growing body of experimental research has linked its exposure to red blood cell impairment. However, the potential toxicity of glyphosate exposure on erythrocytes in th…
View article: The role of angiotensin I-converting enzyme gene polymorphism and global DNA methylation in the negative associations between urine di-(2-ethylhexyl) phthalate metabolites and serum adiponectin in a young Taiwanese population
The role of angiotensin I-converting enzyme gene polymorphism and global DNA methylation in the negative associations between urine di-(2-ethylhexyl) phthalate metabolites and serum adiponectin in a young Taiwanese population Open
Background Adiponectin is a key protein produced in adipose tissue, with crucial involvement in multiple metabolic processes. Di-(2-ethylhexyl) phthalate (DEHP), one of the phthalate compounds used as a plasticizer, has been shown to decre…
View article: Association of Urinary Lead and Cadmium Levels, and Serum Lipids with Subclinical Arteriosclerosis: Evidence from Taiwan
Association of Urinary Lead and Cadmium Levels, and Serum Lipids with Subclinical Arteriosclerosis: Evidence from Taiwan Open
Background: Exposure to lead and cadmium has been linked to changes in lipid metabolism and the development of arteriosclerosis, but the role of lipoprotein profiles in this relationship is not well understood, including the potential role…
View article: Global DNA methylation mediates the association between serum perfluorooctane sulfonate and carotid intima-media thickness in young and middle-aged Taiwanese populations
Global DNA methylation mediates the association between serum perfluorooctane sulfonate and carotid intima-media thickness in young and middle-aged Taiwanese populations Open
Our results showed that PFOS exposure has direct associations on arteriosclerosis and indirect direct associations on arteriosclerosis through DNA methylation. The results suggest that DNA methylation might regulate the relationship betwee…
Urine Di-(2-ethylhexyl) Phthalate Metabolites Are Independently Related to Body Fluid Status in Adults: Results from a U.S. Nationally Representative Survey Open
Purpose: Di-(2-ethylhexyl) phthalate (DEHP) has been utilized in many daily products for decades. Previous studies have reported that DEHP exposure could induce renin–angiotensin–aldosterone system activation and increase epithelial sodium…
Degradation of Tetracycline Degradation by a Mercury UV Lamp Coupled with an Ultrafine-Bubbles Ozone Gas Producer Open
There are currently more than 4,000 medicines are used worldwide, with an estimated total global antibiotic consumption of 100,000-200,000 tons per year.These compounds may be released in large quantities into the environment due to overco…