Ching‐Yu Tseng
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View article: Genomic characterization and evolutionary analysis of three bovine viral diarrhea virus 1b strains from Taiwan, highlighting genomic evidence of cytopathic evolution
Genomic characterization and evolutionary analysis of three bovine viral diarrhea virus 1b strains from Taiwan, highlighting genomic evidence of cytopathic evolution Open
View article: A naturally occurring NS1 variant with effector domain deletion gains growth advantages in influenza virus infection
A naturally occurring NS1 variant with effector domain deletion gains growth advantages in influenza virus infection Open
High pathogenicity avian influenza virus (HPAIV) poses major threats to both poultry health and public safety. The viral nonstructural protein 1 (NS1) plays a crucial role in counteracting innate immunity. NS1 typically consists of approxi…
View article: Enhanced detection of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) antibodies in various animal species using oligomeric nucleocapsid protein-based diagnostics
Enhanced detection of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) antibodies in various animal species using oligomeric nucleocapsid protein-based diagnostics Open
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) is a zoonotic pathogen that affects various animal species, often asymptomatically, while causing fatal disease in humans. Current serological tests are limited, which led to the de…
View article: Development of attenuated Orf virus as a safe oncolytic viral vector for nasopharyngeal carcinoma treatment
Development of attenuated Orf virus as a safe oncolytic viral vector for nasopharyngeal carcinoma treatment Open
View article: Development of a tag-free plant-made interferon gamma production system with improved therapeutic efficacy against viruses
Development of a tag-free plant-made interferon gamma production system with improved therapeutic efficacy against viruses Open
Plants offer a promising platform for cost-effective production of biologically active therapeutic glycoproteins. In previous studies, we have developed a plant expression system based on Bamboo mosaic virus (BaMV) by incorporating secreto…
View article: Nuzhenide of the Fruits of Nvzhenzi (Ligustrum Lucidum Ait.) is a Functional Analog of Ghrelin
Nuzhenide of the Fruits of Nvzhenzi (Ligustrum Lucidum Ait.) is a Functional Analog of Ghrelin Open
View article: NS2 is a key determinant of compatibility in reassortant avian influenza virus with heterologous H7N9-derived NS segment
NS2 is a key determinant of compatibility in reassortant avian influenza virus with heterologous H7N9-derived NS segment Open
Influenza A viruses are common pathogens with high prevalence worldwide and potential for pandemic spread. While influenza A infections typically elicit robust cellular innate immune responses, the non-structural protein 1 (NS1) antagonize…
View article: Deletion of gene OV132 attenuates Orf virus more effectively than gene OV112
Deletion of gene OV132 attenuates Orf virus more effectively than gene OV112 Open
View article: Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist
Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist Open
The growth hormone secretagogue receptor-1a (GHSR1a) is the endogenous receptor for ghrelin. Activation of GHSR1a participates in many physiological processes including energy homeostasis and eating behavior. Due to its transitory half-lif…
View article: The Analysis with Quantitative Indexes for Public’s Awareness of Radiation Knowledge in Taiwan
The Analysis with Quantitative Indexes for Public’s Awareness of Radiation Knowledge in Taiwan Open
(1) Background: The purpose of this study was to evaluate the radiation awareness level of the public in Taiwan. (2) Methods: This study designed an online survey form to investigate the radiation awareness level with six topics: basic kno…
View article: CrossDTR: Cross-view and Depth-guided Transformers for 3D Object Detection
CrossDTR: Cross-view and Depth-guided Transformers for 3D Object Detection Open
To achieve accurate 3D object detection at a low cost for autonomous driving, many multi-camera methods have been proposed and solved the occlusion problem of monocular approaches. However, due to the lack of accurate estimated depth, exis…
View article: 3rd Place Solution for NeurIPS 2021 Shifts Challenge: Vehicle Motion\n Prediction
3rd Place Solution for NeurIPS 2021 Shifts Challenge: Vehicle Motion\n Prediction Open
Shifts Challenge: Robustness and Uncertainty under Real-World Distributional\nShift is a competition held by NeurIPS 2021. The objective of this competition\nis to search for methods to solve the motion prediction problem in\ncross-domain.…
View article: 3rd Place Solution for NeurIPS 2021 Shifts Challenge: Vehicle Motion Prediction
3rd Place Solution for NeurIPS 2021 Shifts Challenge: Vehicle Motion Prediction Open
Shifts Challenge: Robustness and Uncertainty under Real-World Distributional Shift is a competition held by NeurIPS 2021. The objective of this competition is to search for methods to solve the motion prediction problem in cross-domain. In…
View article: The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection
The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection Open
Cellular double‐stranded RNA‐binding proteins (DRBPs) play important roles in the regulation of innate immune responses and microRNA (miRNA) biogenesis. The current study aimed to understand whether OV20.0, a DRBP of orf virus (ORFV), is i…
View article: K160 in the RNA‐binding domain of the orf virus virulence factor OV20.0 is critical for its functions in counteracting host antiviral defense
K160 in the RNA‐binding domain of the orf virus virulence factor OV20.0 is critical for its functions in counteracting host antiviral defense Open
The OV20.0 virulence factor of orf virus antagonizes host antiviral responses. One mechanism through which it functions is by inhibiting activation of the dsRNA‐activated protein kinase R (PKR) by sequestering dsRNA and by physically inter…
View article: Establishment and characterization of transformed goat primary cells by expression of simian virus 40 large T antigen for orf virus propagations
Establishment and characterization of transformed goat primary cells by expression of simian virus 40 large T antigen for orf virus propagations Open
Due to the limited host range of orf virus (ORFV), primary cells derived from its natural hosts, such as goats and sheep, are recommended for isolation and propagation of wild type ORFV. This situation limits the option for the study of vi…
View article: Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication
Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication Open
Viruses evolve specific strategies to counteract host innate immunity. ORFV, an important zoonotic pathogen, encodes OV20.0 to suppress PKR activation via multiple mechanisms, including interactions with PKR and two PKR activators. In this…