Chloé Bost
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View article: Unmasking Anti‐<scp>CASPR2</scp> Syndrome in a Patient Treated for Myasthenia Gravis in the Era of New Treatments
Unmasking Anti‐<span>CASPR2</span> Syndrome in a Patient Treated for Myasthenia Gravis in the Era of New Treatments Open
Introduction Myasthenia gravis (MG) is an autoimmune disorder characterised by autoantibodies against the acetylcholine receptor (AChR‐Ab). Morvan syndrome (MoS) is a rarer autoimmune disease with neuromyotonia, dysautonomia and encephalop…
View article: Isolated Choreic Manifestations Indicative of Anti‐Amphiphysin Antibody‐Related Encephalitis in Breast Cancer
Isolated Choreic Manifestations Indicative of Anti‐Amphiphysin Antibody‐Related Encephalitis in Breast Cancer Open
International audience
View article: The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients
The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients Open
coupling anti-dsDNA with anti-Chr Ab detection at disease initiation/flare allows definition of endotypes, which is useful to follow disease activity, predict lupus nephritis/serositis, and anticipate therapeutic response in the DP + group.
View article: A challenging case of cerebellar ataxia associated with oro facial dominant chorea
A challenging case of cerebellar ataxia associated with oro facial dominant chorea Open
International audience
View article: “Stream of Consciousness Impairment” in Severe Amnesia: A Novel Aspect of Temporal Disorientation
“Stream of Consciousness Impairment” in Severe Amnesia: A Novel Aspect of Temporal Disorientation Open
Orientation in time is a central aspect of human cognition. Because orientation in time is intimately related to autobiographical episodic memory, most amnesic patients suffer from temporal disorientation. Patients with severe anterograde …
View article: Unexpected discovery of CRP analytical interference: A case report
Unexpected discovery of CRP analytical interference: A case report Open
International audience
View article: Urinary soluble CD163 is useful as “liquid biopsy” marker in lupus nephritis at both diagnosis and follow-up to predict impending flares
Urinary soluble CD163 is useful as “liquid biopsy” marker in lupus nephritis at both diagnosis and follow-up to predict impending flares Open
Lupus nephritis (LN) diagnosis and follow-up requires noninvasive biomarkers. Therefore, the added value of coupling the urinary soluble (s)CD163/creatinuria ratio with serological markers was evaluated in a real-world clinical practice. T…
View article: Increased levels of circulating soluble CD226 in multiple sclerosis
Increased levels of circulating soluble CD226 in multiple sclerosis Open
Background: The glycoprotein CD226 plays a key role in regulating immune cell function. Soluble CD226 (sCD226) is increased in sera of patients with several chronic inflammatory diseases but its levels in neuroinflammatory diseases such as…
View article: Autoimmune Bullous Disorders induced by Cyclin-Dependent Kinase 4/6 inhibitors – first case series from the EADV Task Force “Dermatology for Cancer Patients”
Autoimmune Bullous Disorders induced by Cyclin-Dependent Kinase 4/6 inhibitors – first case series from the EADV Task Force “Dermatology for Cancer Patients” Open
Background: Cyclin-Dependent Kinase 4/6 inhibitors have revolutionized the standard of care in women with hormone-receptor positive, locally advanced or metastatic breast cancer. Cutaneous adverse events have been reported in about 15 % of…
View article: Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell–Mediated Neuroinflammation
Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell–Mediated Neuroinflammation Open
Therefore, perforin-dependent cytotoxicity plays a key role in the death of BBB-ECs inflicted by autoreactive CD8 T cells in a preclinical model and potentially represents a therapeutic target for CD8 T cell-mediated neuroinflammatory dise…
View article: Cerebrospinal fluid YKL‐40 level evolution is associated with autoimmune encephalitis remission
Cerebrospinal fluid YKL‐40 level evolution is associated with autoimmune encephalitis remission Open
Objective Because of its heterogeneity in clinical presentation and course, predicting autoimmune encephalitis (AIE) evolution remains challenging. Hence, our aim was to explore the correlation of several biomarkers with the clinical cours…
View article: Severe pemphigoid nodularis successfully treated with dupilumab
Severe pemphigoid nodularis successfully treated with dupilumab Open
Pemphigoid nodularis (PN) is a variant of bullous pemphigoid (BP) associating clinical features of prurigo and an immunological profile of BP.1 We present a case of PN successfully treated with dupilumab. A 76-year-old female patient with …
View article: Case Report: Presence of Anti-MAG in the CSF Can Be Associated With a Neurodegenerative Process With Frontal Involvement
Case Report: Presence of Anti-MAG in the CSF Can Be Associated With a Neurodegenerative Process With Frontal Involvement Open
Background Autoimmune encephalitis (AIE) is an increasingly broad nosological framework that may clinically mimic neurodegenerative diseases (NDDs). Cases Reported We describe here the clinical, radiological, electrophysiological, and biol…
View article: Causal risk and protective factors in rheumatoid arthritis: A genetic update
Causal risk and protective factors in rheumatoid arthritis: A genetic update Open
The characterization of risk and protective factors in complex diseases such as rheumatoid arthritis (RA) has evolved from epidemiological studies, which test association, to the use of Mendelian randomization approaches, which test direct…
View article: COVID-19–associated acute necrotising encephalopathy successfully treated with steroids and polyvalent immunoglobulin with unusual IgG targeting the cerebral fibre network
COVID-19–associated acute necrotising encephalopathy successfully treated with steroids and polyvalent immunoglobulin with unusual IgG targeting the cerebral fibre network Open
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View article: Immunological Bases of Paraneoplastic Cerebellar Degeneration and Therapeutic Implications
Immunological Bases of Paraneoplastic Cerebellar Degeneration and Therapeutic Implications Open
Paraneoplastic cerebellar degeneration (PCD) is a rare immune-mediated disease that develops mostly in the setting of neoplasia and offers a unique prospect to explore the interplay between tumor immunity and autoimmunity. In PCD, the dele…
View article: Two Cases of Late-Onset Anti-NMDAr Auto-Immune Encephalitis After Herpes Simplex Virus 1 Encephalitis
Two Cases of Late-Onset Anti-NMDAr Auto-Immune Encephalitis After Herpes Simplex Virus 1 Encephalitis Open
International audience
View article: Leucine-Rich Glioma-Inactivated 1 Encephalitis: Broadening the Sphere
Leucine-Rich Glioma-Inactivated 1 Encephalitis: Broadening the Sphere Open
Background: Leucine-rich glioma-inactivated 1 (LGI1) encephalitis is a rare entity. Its typical features are seizures, faciobrachial dystonic seizures (FBDS), cognitive impairment, and personality changes. Case report: We report the case o…