Chloé Dumot
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View article: Madison Objective Self-Assessment Tool: A Reliable and User-Friendly Approach for Objective Self-Assessment in Microvascular Anastomosis Training
Madison Objective Self-Assessment Tool: A Reliable and User-Friendly Approach for Objective Self-Assessment in Microvascular Anastomosis Training Open
BACKGROUND AND OBJECTIVES: Thorough and objective assessment is of utmost importance for any microsurgical laboratory training, allowing trainees to identify areas needing further improvement. The ideal assessment tool should be objective,…
View article: Editorial: Non-specific symptoms of unruptured intracranial aneurysms-new concepts in pathophysiology, hemodynamics and potential warning signs
Editorial: Non-specific symptoms of unruptured intracranial aneurysms-new concepts in pathophysiology, hemodynamics and potential warning signs Open
View article: A self-healing radiopaque hyaluronic acid hydrogel as a new injectable biomaterial for precision medicine in osteoarthritis
A self-healing radiopaque hyaluronic acid hydrogel as a new injectable biomaterial for precision medicine in osteoarthritis Open
Rationale: Osteoarthritis (OA) is a degenerative disease affecting cartilage, synovium and bone, that is a major cause of pain and disability. Intra-articular injection of hyaluronic acid (HA) derivatives, also known as viscosupplem…
View article: Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): an international, multicentric study
Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): an international, multicentric study Open
Brainstem cerebral cavernous malformations (CCM) are clinically more aggressive compared to superficial CCMs. Due to their location, resection can be challenging, making stereotactic radiosurgery (SRS) an attractive alternative for symptom…
View article: Risk of new tumor, carotid stenosis, and stroke after stereotactic radiosurgery for pituitary tumor: A multicenter study of 2254 patients with imaging follow-up
Risk of new tumor, carotid stenosis, and stroke after stereotactic radiosurgery for pituitary tumor: A multicenter study of 2254 patients with imaging follow-up Open
Background A higher risk of secondary brain tumor, carotid stenosis, and stroke has been reported after conventional sella irradiation for pituitary neuroendocrine tumors (PitNET). Stereotactic radiosurgery (SRS), which is a more focused a…
View article: Predictors of Progression in a Series of 81 Adult Patients Surgically Managed for an Intracranial Hemangioblastoma: Implications for the Postoperative Follow-Up
Predictors of Progression in a Series of 81 Adult Patients Surgically Managed for an Intracranial Hemangioblastoma: Implications for the Postoperative Follow-Up Open
The aim was to identify predictors of progression in a series of patients managed for an intracranial hemangioblastoma, in order to guide the postoperative follow-up modalities. The characteristics of 81 patients managed for an intracrania…
View article: Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): An International, Multicentric Study
Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): An International, Multicentric Study Open
Introduction: Brainstem cerebral cavernous malformations (CCM) are clinically more aggressive compared to superficial CCMs. Due to their location, resection can be challenging, making stereotactic radiosurgery (SRS) an attractive alternati…
View article: Multimodal neuromonitoring of a brain death with electrophysiological markers of cortical and subcortical loss of functions
Multimodal neuromonitoring of a brain death with electrophysiological markers of cortical and subcortical loss of functions Open
Brain death, characterized by the permanent cessation of all brain functions including the brainstem, is subject to varying diagnostic criteria internationally. In France, the confirmation of the clinical criteria requires ancillary tests …
View article: Stereotactic radiosurgery for nonfunctioning pituitary tumor: A multicenter study of new pituitary hormone deficiency
Stereotactic radiosurgery for nonfunctioning pituitary tumor: A multicenter study of new pituitary hormone deficiency Open
Background Stereotactic radiosurgery (SRS) is used to treat recurrent or residual nonfunctioning pituitary neuroendocrine tumors (NFPA). The objective of the study was to assess imaging and development of new pituitary hormone deficiency. …
View article: Stereotactic radiosurgery for haemorrhagic cerebral cavernous malformation: a multi-institutional, retrospective study
Stereotactic radiosurgery for haemorrhagic cerebral cavernous malformation: a multi-institutional, retrospective study Open
Background Cerebral cavernous malformations (CCMs) frequently manifest with haemorrhages. Stereotactic radiosurgery (SRS) has been employed for CCM not suitable for resection. Its effect on reducing haemorrhage risk is still controversial.…
View article: A novel injectable radiopaque hydrogel with potent properties for multicolor CT imaging in the context of brain and cartilage regenerative therapy
A novel injectable radiopaque hydrogel with potent properties for multicolor CT imaging in the context of brain and cartilage regenerative therapy Open
Cell therapy is promising to treat many conditions, including neurological and osteoarticular diseases. Encapsulation of cells within hydrogels facilitates cell delivery and can improve therapeutic effects. However, much work remains to be…
View article: Gut microbiota and stroke: New avenues to improve prevention and outcome
Gut microbiota and stroke: New avenues to improve prevention and outcome Open
Despite major recent therapeutic advances, stroke remains a leading cause of disability and death. Consequently, new therapeutic targets need to be found to improve stroke outcome. The deleterious role of gut microbiota alteration (often m…
View article: High-resolution synchrotron K-edge subtraction CT allows tracking and quantifying therapeutic cells and their scaffold in a rat model of focal cerebral injury and can serve as a reference for spectral photon counting CT
High-resolution synchrotron K-edge subtraction CT allows tracking and quantifying therapeutic cells and their scaffold in a rat model of focal cerebral injury and can serve as a reference for spectral photon counting CT Open
Background: The objective of this study was to demonstrate that synchrotron K-edge subtraction tomography (SKES-CT) can simultaneously track therapeutic cells and their encapsulating carrier, in vivo, in a rat model of focal …
View article: Facial Nerve Schwannoma Treatment with Stereotactic Radiosurgery (SRS) versus Resection followed by SRS: Outcomes and a Management Protocol
Facial Nerve Schwannoma Treatment with Stereotactic Radiosurgery (SRS) versus Resection followed by SRS: Outcomes and a Management Protocol Open
Background Stereotactic radiosurgery (SRS) and resection are treatment options for patients with facial nerve schwannomas without mass effect. Objective This article evaluates outcomes of patients treated with SRS versus resection + SRS. M…
View article: Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies
Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies Open
The activation of phagocytic cells is a hallmark of many neurological diseases. Imaging them in their 3-dimensional cerebral environment over time is crucial to better understand their role in disease pathogenesis and to monitor their pote…
View article: An iodine labeled injectable hyaluronic acid hydrogel for an in vivo bicolor x-ray monitoring of a biomimetic scaffold in brain regeneration cell therapy
An iodine labeled injectable hyaluronic acid hydrogel for an in vivo bicolor x-ray monitoring of a biomimetic scaffold in brain regeneration cell therapy Open
International audience
View article: Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke
Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke Open
View article: Stereotactic radiosurgery for sellar solitary fibrous tumors: Case report and literature review.
Stereotactic radiosurgery for sellar solitary fibrous tumors: Case report and literature review. Open
View article: Multiparametric MRI for the preclinical evaluation of therapeutic approaches of ischemic stroke at the acute and chronic stage
Multiparametric MRI for the preclinical evaluation of therapeutic approaches of ischemic stroke at the acute and chronic stage Open
L’accident vasculaire cérébral est un enjeu majeur de santé publique puisqu’il s’agit de la deuxième cause de mortalité mondiale. Dans le cadre de l’AVC ischémique, qui représente 80% des causes d’AVC, la reperfusion, qu‘elle soit pharmaco…
View article: Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke
Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke Open
With the aim of designing a preclinical study evaluating an intracerebral cell-based therapy for stroke, an observational study was performed in the rat suture model of ischemic stroke. Objectives were threefold: (i) to characterize neurof…
View article: Characteristics and management of hydrocephalus in adult patients with cerebellar glioblastoma: lessons from a French nationwide series of 118 cases
Characteristics and management of hydrocephalus in adult patients with cerebellar glioblastoma: lessons from a French nationwide series of 118 cases Open
View article: Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke
Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke Open
The purpose of this study is to propose and validate a preclinical in vivo magnetic resonance imaging (MRI) tool to monitor neuroinflammation following ischemic stroke, based on injection of a novel multimodal nanoprobe, NanoGd, specifical…
View article: Tracking cells in the brain of small animals using synchrotron multi-spectral phase contrast imaging
Tracking cells in the brain of small animals using synchrotron multi-spectral phase contrast imaging Open
International audience
View article: Management, functional outcomes and survival in a French multicentric series of 118 adult patients with cerebellar glioblastoma
Management, functional outcomes and survival in a French multicentric series of 118 adult patients with cerebellar glioblastoma Open
View article: Radiosurgery for unruptured brain arteriovenous malformations in the pre-ARUBA era: long-term obliteration rate, risk of hemorrhage and functional outcomes
Radiosurgery for unruptured brain arteriovenous malformations in the pre-ARUBA era: long-term obliteration rate, risk of hemorrhage and functional outcomes Open
View article: Arteriovenous malformation drained into a developmental venous anomaly: A case report and up-dated literature review
Arteriovenous malformation drained into a developmental venous anomaly: A case report and up-dated literature review Open
View article: Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study
Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study Open
Reperfusion is the only existing strategy for patients with acute ischemic stroke, however it causes further brain damage itself. A feasible therapy targeting reperfusion injury is remote ischemic conditioning (RIC). This was a two-centre,…
View article: Procedures performed during neurosurgery residency in Europe
Procedures performed during neurosurgery residency in Europe Open
Background In a previous article ( 10.1007/s00701-019-03888-3 ), preliminary results of a survey, aiming to shed light on the number of surgical procedures performed and assisted during neurosurgery residency in Europe were reported. We he…
View article: Alterations of cerebral microcirculation in peritumoral edema: feasibility of in vivo sidestream dark-field imaging in intracranial meningiomas
Alterations of cerebral microcirculation in peritumoral edema: feasibility of in vivo sidestream dark-field imaging in intracranial meningiomas Open
Background Intracranial meningiomas display a variable amount of peritumoral brain edema (PTBE), which can significantly impact perioperative morbidity. The role of microcirculatory disturbances in the pathogenesis of PTBE is still debated…
View article: Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage
Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage Open
Rationale & aim: Various types of cell therapies are currently under investigation for the treatment of ischemic stroke patients. To bridge the gap between cell administration and therapeutic outcome, there is a need for non-invasiv…